An introduction to underlying principles and experimental procedures using the newest strategies and techniques for obtaining extensive NMR assignments in biopolymers based on NMR data and the primary structure. Includes an extensive and non-mathematical discussion of 2D NMR and Nulcear Overhauser effects; resonance assignments and structure determination in proteins; and resonance assignments and structure determination in nucleic acids. Enables specialists and non-specialists to evaluate the potentialities and limitations of the method.
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An introduction to underlying principles and experimental procedures using the newest strategies and techniques for obtaining extensive NMR assignments in biopolymers based on NMR data and the primary structure. Includes an extensive and non-mathematical discussion of 2D NMR and Nulcear Overhauser effects; resonance assignments and structure determination in proteins; and resonance assignments and structure determination in nucleic acids. Enables specialists and non-specialists to evaluate the potentialities and limitations of the method.
About the Author
Kurt Wuthrich was a co-recipient of the 2003 Nobel Prize in Chemistry for his work on nuclear magnetic resonance technology and its application to protein analysis.
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Most Helpful Customer Reviews
5 of 6 people found the following review helpful:
4.0 out of 5 stars
from a protein spectroscopist,
By A Customer
This review is from: NMR of Proteins and Nucleic Acids (Baker Lecture Series) (Hardcover)
This book is dated now in its techniques and doesn't contain the newer methods, but it still has very valuable basic information that makes it a good addition to anyone's library.
3.0 out of 5 stars
Good Technicals, be prepared to be bored,
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This review is from: NMR of Proteins and Nucleic Acids (Baker Lecture Series) (Hardcover)
If I could I would give it 3.5 stars. First, it is an absolutely great book for technical aspects of proton NMR, the techniques described are still in full use to day, and has changed little if any from the date this book is written. Anyone who does NMR frequently is likely to own this book. As far as a reference book is a must for anyone serious about NMR. And just like a reference book it is an absolute snooze fest. Good bed time reading, if one wanted to dream about coupling.
This is not a book for beginners, it is highly technical, highly mathematically driven, and full of jargon.
4.0 out of 5 stars
solid book on biomolecular NMR,
This review is from: NMR of Proteins and Nucleic Acids (Baker Lecture Series) (Hardcover)
This book is old, but it still contains many usefull details in the NMR spectroscopy of macromolecules. This book is highly recommended for the beginners in this field.
I would like to see new and actual version of this book, which is really needed.
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Inside This Book
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First Sentence:
The first nuclear magnetic resonance (NMR) experiments with biopolymers were described over 30 years ago, and the potentialities of the method for studies of structure and dynamics of proteins and nucleic acids were long anticipated. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
nonlabile protons, spatial structure determination, scalar coupling connectivities, lac headpiece, short sequential distances, spin system identifications, assignment pathway, intranucleotide distances, subspectra containing, intrinsic exchange rates, helix identification, sequential connectivities, ribose protons, cross peaks, dipeptide segments, common amino acid residues, resonance assignments, sequential assignments, proton types, skew diagonal, diagonal peaks, backbone protons, amino protons, connectivity diagram, imino protons Key Phrases - Capitalized Phrases (CAPs): (learn more)
American Chemical Society, Biochemical Nomenclature New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
The first nuclear magnetic resonance (NMR) experiments with biopolymers were described over 30 years ago, and the potentialities of the method for studies of structure and dynamics of proteins and nucleic acids were long anticipated. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
nonlabile protons, spatial structure determination, scalar coupling connectivities, lac headpiece, short sequential distances, spin system identifications, assignment pathway, intranucleotide distances, subspectra containing, intrinsic exchange rates, helix identification, sequential connectivities, ribose protons, cross peaks, dipeptide segments, common amino acid residues, resonance assignments, sequential assignments, proton types, skew diagonal, diagonal peaks, backbone protons, amino protons, connectivity diagram, imino protons Key Phrases - Capitalized Phrases (CAPs): (learn more)
American Chemical Society, Biochemical Nomenclature New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 7
books:
See all 7 books this book cites
- Biological Magnetic Resonance by Lawrence Berliner in Back Matter (1), Back Matter (2), and Back Matter (3)
- Biological Applications of Magnetic Resonance by R. G. Shulman in Back Matter (1), Back Matter (2), and Back Matter (3)
- Bioorganic Chemistry by Yuri A. Ovchinnikov in Back Matter
- Nuclear Magnetic Resonance (Oxford Chemistry Primers) by P. J. Hore in Back Matter
- Nuclear Magnetic Resonance in Biochemistry: Applications to Enzyme Systems by Raymond A. Dwek in Back Matter
See all 7 books this book cites
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