Customer Reviews

Proteins: Structures and molecular properties

5 star:		(1)
4 star:		(3)
3 star:		(0)
2 star:		(1)
1 star:		(0)

 

 

I have been using this text as a supplement in a biophysics course and have found it very helpful. The text discusses physical properties of interactions within a polypeptide chain as well as with the environment. This book goes into protein folding, determination of evolutionary relationships between proteins, enzymology, methods for determining structure (like NMR, X-Ray diff), and is an excellent graduate or advanced undergraduate text.

This text has been the standard for recent offerings of an upper level Protein Chemistry course. The organization of the chapters is logical and I like the format of the questions at the end of the chapters. Because this text lacks color images, my professor supplemented the Creighton book with a smaller text by Petsko and Ringe, which also has nice color illustrations and stereo images.

This book by Creighton is one of the top two books on protein folding. The other is by Alan Fersht.

This book tackles proteins from the chemistry of its amino acids, via folding, biophysical properties, evolution, degradation, biosynthesis, structural determination, structure-function properties and more. Every chapter is as thorough as the format allows, and since it is clear that Chreighton set out to write a veritable flagship of a book, each chapter is really comprehensive. Sure, some things have changed since 1992, for instance within protein folding, but many of the books statements about this phenomenon are still valid abstractions for many proteins. There are some trivial errors when Chreighton deals with specialized techniques such as NMR, but nothing crippling. Chreighton is still one of the most useful books in my bookshelf. If there would be newer editions available I'd give them full score.

Please, I don't buy this book except if you want for some reference. I bought my graduate school, for me were complete unuseful.