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Purification of Laboratory Chemicals, Fourth Edition [Hardcover]

D D PERRIN (Author), W.L.F. Armarego (Author)
4.0 out of 5 stars  See all reviews (5 customer reviews)


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Book Description

October 16, 1996 0750628391 978-0750628396 4
The purpose of this book is to help chemists, biochemists and other scientists purify the chemical reagents which they use in their work. Despite the fact that commercially available chemicals are often of a very high quality, and quite satisfactory for some applications within science and technology, it is becoming almost as important to know what impurities are present and make allowance for them as to remove them completely. This book will show you how.


The main chapters describe processes, taken from the literature, for purifying over 4000 organic and 750 inorganic and organometallic commercially available chemicals. Further chapters describe the methods and techniques currently used for purification in laboratories and prescribed in the text. Methods for purifying classes of chemicals where specific compounds are not treated individually in the text are dealt with in a separate chapter. This considerably expanded and revised fourth edition includes much new material dealing with modern reagents for natural products chemistry, protein biochemistry and molecular biology. It also includes many individual compounds not previously covered, and more information is given for most entries, including melting and boiling points, molecular weights, refractive indexes, densities and CAS registry numbers, as well as likely contaminants and storage conditions in appropriate cases.

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Editorial Reviews

Review

' The revised edition has been updated to include compounds not
previously covered and new material dealing with reagents for natural
product chemistry, protein biochemistry and molecular biology'.

Book Description

Purification of Laboratory Chemicals is vital for minimizing potentially dangerous reactions, as well as maximizing the integrity of chemicals used to process a product that must adhere to rigorous scientific standards. --This text refers to an out of print or unavailable edition of this title.

Product Details

  • Hardcover: 448 pages
  • Publisher: Butterworth-Heinemann; 4 edition (October 16, 1996)
  • Language: English
  • ISBN-10: 0750628391
  • ISBN-13: 978-0750628396
  • Product Dimensions: 12.2 x 8.8 x 1.5 inches
  • Shipping Weight: 3.5 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (5 customer reviews)
  • Amazon Best Sellers Rank: #529,058 in Books (See Top 100 in Books)

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19 of 20 people found the following review helpful:
4.0 out of 5 stars Great for the Organic Chemist, December 31, 1998
Like Carey & Sundberg, Jerry March, the Aldrich catalog, and the Merck Index, (etc.), this book should be a benchmate for the Organic Chemist. It is very good when one requires the purification of reagents, or the drying/purification of solvents. The protocols for purification are usually pretreatment followed by distillation or recrystallization, and can be carried out to give anywhere from moderately pure material, to giving the pure, pure substance.

Excellent for the research organic chemistry graduate student or the pharmaceutical industrial research chemist who likes to start with the purest materials, so as to leave only the investigative variables open to question.

However, in industry, although FedEx-ing new and pure reagents (and disposal of the old questionable ones!) is the easiest and encouraged method for research, it is often found that purification is totally appropriate--in these instances, Purification of Laboratory Chemicals (D.D. Perrin & W.L.F. Armarego) is highly recommended.

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11 of 11 people found the following review helpful:
4.0 out of 5 stars An Absolute Essential for Chemists!, November 17, 2000
As a chemist, I am often in need of techniques for purification of various chemicals. Often time is a constraint and the "best" technique may be too time consuming, if one even knows what it is. This text offers several alternatives to the purificatin of most common compounds (especially solvents), including the best way to make the compound pure as well as other known techniques. One can then choose, based on the reaction one is doing whether one needs to use the best techniques or the fastest technique to get mostly pure material or somewhere inbetween. Unfortunately, often the text does not list the actual percent purity that each technique can yield (though it is often easy enough to guess which methodology will yield the best results.) An invaluable resource for any chemist, but especially for graduate students.
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5 of 6 people found the following review helpful:
5.0 out of 5 stars Great for the "Synthetic" Chemist, June 5, 2000
By 
Craig MACKINNON (Thunder Bay, Ontario Canada) - See all my reviews
This is an indispensible resource for any synthetic chemist, either organic or inorganic (not sure about the biochemical section). This book has concise, informative entries on the purification of a vast number of common solvents and reagents. I don't know how any chemist can survive without having this on his/her bookshelf!
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Inside This Book (learn more)
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First Sentence:
Purity is a matter of degree. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
fractional distn, distd water, vacuum distd, white ppte, pet ether, vac desiccator, ether soln, saturated aqueous soln, distil under vacuum, wash with aqueous, ppm resp, glass helices, alumina before use, olefinic impurities, alkaline soln, distillate solidifies, soln containing, efficient fume cupboard, been recrystallised, likely impurities, fractional freezing, acid crystallises, first coloration, hot glacial acetic acid, saturated soln
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Chem Soc, Org Chem, Chem Ber, Phys Chem, Biol Chem, Anal Chem, Org Synth Coll Vol, Justus Liebigs Ann Chem, New York, Heiv Chim Acta, Hely Chim Acta, Tetrahedron Lett, Faraday Trans, Biochem Prep, Anal Biochem, Acta Chem Scand, Methods Enzymol, Inorg Synth, Handbook of Preparative Inorganic Chemistry, Chem Commun, Trans Faraday Soc, Biochim Biophys Acta, Chem Ind, Appl Chem, Dalton Trans
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