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The Quinolones, Third Edition [Hardcover]

Vincent T. Andriole (Author)

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Book Description

September 25, 2000 0120595176 978-0120595174 3
Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease.
Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research.
Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field.

Key Features
* Eagerly anticipated updated edition of noted title covering synthetic microbial agents that are useful against infectious disease, particularly those caused by bacteria
* Edited by one of the foremost experts in the field of quinolone research and infectious disease
* History of quinolones, chemistry & mechanisms of action, pharmacology, safety aspects
* Role of quinolones in treating various types of infections, including respiratory infections, gastrointestinal infections, urinary tract infections, prostatitis, STDs and bacterial meningitis as well as their use in immunocompromised patients

Editorial Reviews

From the Back Cover

Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title, The Quinolones will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up to date quinolones reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. It is the eagerly anticipated fully revised edition of the standard reference in the field.
Key Features
* Eagerly anticipated updated edition of noted title covering synthetic microbial agents that are useful against infectious disease, particularly those caused by bacteria.
* Edited by one of the foremost experts in the field of quinolone research and infectious disease
* History of quinolones, chemistry & mechanisms of action, pharmacology, safety aspects
* Role of quinolones in treating various types of infections, including respiratory infections, gastrointestinal infections, urinary tract infections, prostatitis, STDs and bacterial meningitis as well as their use in immunocompromised patients.

About the Author

Vincent T. Andriole received his B.S. from College of the Holy Cross, Worcester, Massachusetts, and his M.D. from Yale University School of Medicine, New Haven, Connecticut. He received his post-graduate training at the North Carolina Memorial Hospital, North Carolina Hospital, National Institutes of Health, and Yale University School of Medicine. He has served on the faculty of Yale since 1963, and is currently Professor of Medicine and a member of the Board of Permanent Officers. He has served as Editor for several journals, and is presently the Editor for Mediguide to Infectious Diseases, Cliniguide to Fungal Infections, and Current Opinion in Infectious Diseases. He is the International Adviser for The Journal of Antimicrobial Chemotherapy. He has also served on the Editorial Board and as a Reviewer for numerous journals. Dr. Andriole has been amember of several national committees and is a member of several professional societies; he has won a number of awards and honors. In addition to editing six books, Dr. Andriole has published 176 original articles, 72 reviews and chapters, and 85 abstracts and preliminary notes.


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Inside This Book (learn more)
First Sentence:
The development of quinolone antibacterials, since the discovery of the naphthyridine agent nalidixic acid some 40 years ago [1], has progressed with periods of great clinical innovation, alternating with periods of apparent inactivity following unexpected recognition of rare, but severe, adverse reactions associated with specific agents. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
acute uncomplicated urinary infection, oral quinolone therapy, acute nonobstructive pyelonephritis, new fluoroquinolone trovafloxacin, quinolone arthropathy, newest quinolones, gynecologic tissues, moxifloxacin therapy, oral fleroxacin, quinolone activity, one adverse experience, oral trovafloxacin, new fluoroquinolone antibiotic, quinolone monotherapy, quinolone agents, quinolone nucleus, quinolone binding, prolonged fecal excretion, pipemidic acid, immature beagle dogs, most fluoroquinolones, many quinolones, febrile neutropenic patients, quinolone resistance, quinolone antimicrobial agents
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Agents Chemother, United States, Academic Press, San Francisco, San Diego, New Engl, New York, Third Edition, New Orleans, Hong Kong, Drug Saf, Effect Number Percent, Western Europe, United Kingdom, Drug Res, Excerpta Medica, Peter Ball, Barman Balfour, Department of Medicine, Drugs Exp, Expert Opin, Laboratory Medicine, New Haven, Open Ciprofloxacin, The Netherlands
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