Free Radicals in Biology and Medicine [Paperback]

Barry Halliwell (Author), John Gutteridge (Author)

Book Description

ISBN-10: 019856869X | ISBN-13: 978-0198568698 | Publication Date: May 10, 2007 | Edition: 4

Free Radicals in Biology and Medicine has become a classic text in the field of free radical and antioxidant research since its first publication in 1985.

This latest edition has been comprehensively rewritten and updated (over 80% of the text is new), while maintaining the clarity of its predecessor. There is expanded coverage of isoprostanes and related compounds, mechanisms of oxidative damage to DNA and proteins (and the repair of such damage), the free radical theory of aging and the roles played by reactive species in signal transduction, cell death, human reproduction, and other important biological events. Greater emphasis has also been placed on the methods available to measure reactive species and oxidative damage (and their potential pitfalls), as well as the importance of antioxidants in the human diet.

This book is recommended as a comprehensive introduction to the field for students, clinicians and researchers, and an invaluable companion to all those interested in the role of free radicals in the life and biomedical sciences.

Editorial Reviews

Review

`Review from previous edition "...This new tome has exceeded all my expectations." "...Free Radicals in Biology and Medicine...has always been compulsive reading for all in this area of research whether undergraduate, postgraduate undertaking a PhD programme, clinician, or scientist and a veyr popular text for teachers and students alike...The new volume not only continues this tradition, it is also a superb triumph of a textbook from two eminent leaders in the field and a must for anyone wanting to come to grips with the diverse area of free radical research and its relevance to biology and human disease, or for experts to bring themselves up to date with the areas that they do not normally focus on."' Prof. Catherine Rice-Evans, Guy's, King's and St. Thomas's School of Medicine and Dentistry .

`'this publication conforms the needs of all groups of readers. The 3rd edition of the famous textbook of bioradical science is a remarkable book. In comparison with the 1st Edition it is considerably altered, expanded (936 vs 543 Pages) and updated ... I am not uncritical in my sincere admiration of this unusual book ... If you consider buying a book on reactive oxygen species, this is number one' ' Cell Biology International

About the Author

Professor Barry Halliwell, Department of Pharmacology, King's College, London. John M. C. Gutteridge, Department of Anaesthesia and Intensive Care, Royal Brompton Hospital, London

Product Details

• Paperback: 704 pages
• Publisher: Oxford University Press, USA; 4 edition (May 10, 2007)
• Language: English
• ISBN-10: 019856869X
• ISBN-13: 978-0198568698
• Product Dimensions: 9.6 x 7.4 x 1.9 inches
• Shipping Weight: 4.3 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (6 customer reviews)
• Amazon Best Sellers Rank: #220,489 in Books (See Top 100 in Books)

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Customer Reviews

Most Helpful Customer Reviews

17 of 17 people found the following review helpful:

5.0 out of 5 stars An excellent book for scientists, May 28, 2000

By 

Math PC (Pasadena, CA, USA) - See all my reviews

This review is from: Free Radicals in Biology and Medicine (Paperback)

Free radical biology has become a big research area. This text is definitely a helpful tool for students and professionals alike. Halliwell and Gutteridge are both the "authorities" in free radical research. The book contains the basic concepts of metabolism, metal interactions, free radical formation, and antioxidation. The book then relates these processes (that is, oxidative and nitorsative stresses) to pathological events using various disease paradigms. The text contains good illustrations. It is an excellent reference material for everyone who is entering the field of free radical biology and medicine.

6 of 6 people found the following review helpful:

5.0 out of 5 stars Notes from an Oxymoron, September 24, 2001

By 

Happy researcher (In my office) - See all my reviews

This review is from: Free Radicals in Biology and Medicine (Paperback)

Excellent book that provides a thorough grounding to the field. Keep the updated editions coming every few years and it will continue to stay at the top.

4 of 4 people found the following review helpful:

5.0 out of 5 stars Must have for free radical researchers, June 17, 2008

By 

G. Chuang - See all my reviews
(REAL NAME)   

This review is from: Free Radicals in Biology and Medicine (Paperback)

The 2007 edition of the "free radical bible". I strongly recommend this book to anyone currently in or seeking to enter the field of free radical biology. Are you a grad student writing quals or T32/F32? A post-doc going for PI/K99? A seasoned PI trying for the second R01 related to free radicals? One of the fastest ways for a proposal to get tossed is to propose questionable methods. Simply reviewing Pubmed is insufficient, since many papers also use questionable methods to assay for species such as superoxide or lipid peroxides. With this book one can easily reference the oxidative stress markers of interest and quickly determine a reliable method that is commonly accepted, as well as pinpoint the paper referenced to include in your own reference section.