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Liver Radioembolization with 90Y Microspheres (Medical Radiology / Diagnostic Imaging)
 
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Liver Radioembolization with 90Y Microspheres (Medical Radiology / Diagnostic Imaging) [Hardcover]

José Ignacio Bilbao (Editor), Maximilian F. Reiser (Editor), S. Nag (Foreword)

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Book Description

3540354212 978-3540354215 March 11, 2008 1

This vital text for oncologists and radiotherapists provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. Radioembolization combines embolization (intravascular deployment of particles – microspheres loaded with yttrium-90) and brachytherapy (local administration of radiotherapy), thereby allowing delivery of high doses of beta-radiation specifically to the tumoral area.


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Editorial Reviews

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From the reviews:

"The authors succinctly accomplish their task of summarizing and discussing all facets of hepatic radioembolization in the first book specifically on this topic. … for readers at any level from medical student to advanced practitioner interested in the treatment of liver tumors using radioembolization. … The chapters are concise, well organized and presented in appropriate order which helps readers master this important but complex field of therapy. The images are of excellent quality. … This book provides excellent references as well." (Dan A. Devun, Doody’s Review Service, June, 2008)

From the Back Cover

This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 µm) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice.


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