Volume 30 examines the prominent role of calcium as an intracellular second messenger. Leading investigators review a wide variety of studies on how calcium enters and moves through cells, how it interacts with its many binding proteins, and how calcium and its intracellular receptor, calmodulin, control vital cellular processes. Coverage includes a detailed analysis of the mechanisms by which calcium bound to calmodulin regulates contractile proteins in smooth muscle cells. Close attention is given to the roles of calcium and calmodulin-dependent protein kinases and phosphatases in synaptic signal transduction, protein synthesis, gene expression, programmed cell death, activation of T-lymphocytes, and control of cell division cycles. Other chapters discuss studies using genetically manipulable nonmammalian organisms to further proble the functions of calcium and calmodulin.
Calcium Regulation of Cellular Function, Volume 30
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About the Author
Angus C. Nairn is currently Associate Professor at The Rockefeller University. He has published a large number of papers concerned with the structure and regulation of protein kinases and phosphatases involved in signal transduction, particularly with respect to signalling by calcium.
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Inside This Book
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First Sentence:
This review will summarize calcium control mechanisms in nonexcitable cells, explain regenerative calcium release and calcium waves, and provide examples of the biological significance of calcium waves. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
reduced stringency screening, calmodulin transcription, phosphoinositide messenger system, myocyte types, mutant calmodulins, calcium affinity, blank sweeps, right ventricular myocytes, initiation block, calmodulin gene, apoptotic systems, calmodulin mutants, elongation block, inactivation relationship, protein synthetic rates, calcium ligands, mitotic kinase, gating characteristics, ciliary reversal, calcium induction, latch state, free energy coupling, gating transitions, calcium affinities, calcineurin phosphatase activity Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Acad Sci, Cell Biol, Proc Nat, New York, Biochem Biophys Res Commun, Biochim Biophys Acta, Mol Biol, Means Raven Press, Pflugers Arch, Annu Rev Biochem, Annu Rev Physiol, Cell Sci, Cold Spring Harbor, Membr Biol, Brain Res, C-terminal Ca-binding, Trends Neurosci, Circ Res, Dev Biol, Exp Med, Plenum Press, Trends Biochem Sci, Biophys Chem, Cancer Res New!
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Front Cover | Table of Contents | First Pages | Index | Surprise Me!
This review will summarize calcium control mechanisms in nonexcitable cells, explain regenerative calcium release and calcium waves, and provide examples of the biological significance of calcium waves. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
reduced stringency screening, calmodulin transcription, phosphoinositide messenger system, myocyte types, mutant calmodulins, calcium affinity, blank sweeps, right ventricular myocytes, initiation block, calmodulin gene, apoptotic systems, calmodulin mutants, elongation block, inactivation relationship, protein synthetic rates, calcium ligands, mitotic kinase, gating characteristics, ciliary reversal, calcium induction, latch state, free energy coupling, gating transitions, calcium affinities, calcineurin phosphatase activity Key Phrases - Capitalized Phrases (CAPs): (learn more)
Biol Chem, Acad Sci, Cell Biol, Proc Nat, New York, Biochem Biophys Res Commun, Biochim Biophys Acta, Mol Biol, Means Raven Press, Pflugers Arch, Annu Rev Biochem, Annu Rev Physiol, Cell Sci, Cold Spring Harbor, Membr Biol, Brain Res, C-terminal Ca-binding, Trends Neurosci, Circ Res, Dev Biol, Exp Med, Plenum Press, Trends Biochem Sci, Biophys Chem, Cancer Res New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Surprise Me!
Citations (learn more)
This book cites 9
books:
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- Calcium Regulation of Cellular Function (Advances in Second Messenger and Phosphoprotein Research) by Anthony R. Means in Front Matter (1), Front Matter (2), and Front Matter (3)
- New York, New York! (Baby-Sitters Club Super Special, No. 6) by Ann M. Martin in Front Matter
- The Heart and Cardiovascular System: Scientific Foundations by Harry A. Fozzard on page 79
- Regulation of Smooth Muscle Contraction (Advances in Experimental Medicine & Biology (Springer)) by Robert S. Moreland on page 172
- Intracellular Calcium: Its Universal Role as Regulator (Monographs in Molecular Biophysics and Biochemistry) by Anthony K. Campbell on page 24
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