DNA Repair Protocols (Methods in Molecular Biology) [Plastic Comb]

Daryl S. Henderson (Editor)

Book Description

ISBN-10: 0896035905 | ISBN-13: 978-0896035904 | Publication Date: June 21, 1999 | Edition: 1

Daryl S. Henderson and a team of hands-on experts give time-tested instructions for analyzing a wide range of DNA repair processes and cellular responses to DNA damage, including nucleotide and base excision repair, DNA strand break repair, and mismatch repair. The methods focus on eukaryotic model systems that have made, or have the potential to make, important contributions to our understanding of cellular responses to DNA damage in relation to mutagenesis, carcinogenesis, and the cell cycle. Although mammalian cells predominate, consideration is also given to such important nonmammalian model systems as yeast, C. elegans (nematode), Drosophila (fruitfly), Xenopus (amphibian), and plants. DNA Repair Protocols: Eukaryotic Systems offers the most comprehensive collection of DNA repair protocols available, all step-by-step, optimized, and eminently reproducible with tips. It will serve as the gold-standard reference for both the practical and theoretical aspects of DNA repair studies, encourage the transfer of methodologies between model systems, and stimulate the development of new approaches.

Editorial Reviews

Review

"...It will serve as an essential reference for both the practical and theoretical aspects of DNA repair studies, encourage the transfer of methodologies between model systems, and stimulate the development of new approaches." - Anticancer Research

From the Back Cover

In DNA Repair Protocols: Eukaryotic Systems, Daryl S. Henderson and a team of hands-on experts give time-tested instructions for analyzing a wide range of DNA repair processes and cellular responses to DNA damage, including nucleotide and base excision repair, DNA strand break repair, and mismatch repair. The methods focus on eukaryotic model systems that have made, or have the potential to make, important contributions to our understanding of cellular responses to DNA damage in relation to mutagenesis, carcinogenesis, and the cell cycle. Although mammalian cells predominate, consideration is also given to such important nonmammalian model systems as yeast, C. elegans (nematode), Drosophila (fruitfly), Xenopus (amphibian), and plants.

DNA Repair Protocols: Eukaryotic Systems offers the most comprehensive collection of DNA repair protocols available, all step-by-step, optimized, and eminently reproducible with tips on troubleshooting and avoiding pitfalls. It will serve as the gold-standard reference for both the practical and theoretical aspects of DNA repair studies, encourage the transfer of methodologies between model systems, and stimulate the development of new approaches.

Product Details

• Plastic Comb: 656 pages
• Publisher: Humana Press; 1 edition (June 21, 1999)
• Language: English
• ISBN-10: 0896035905
• ISBN-13: 978-0896035904
• Product Dimensions: 8.9 x 6.5 x 1.3 inches
• Shipping Weight: 2 pounds (View shipping rates and policies)
• Average Customer Review: 5.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #8,136,804 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

4 of 4 people found the following review helpful:

5.0 out of 5 stars DNA Repair Protocols: Eukaryotic Systems, April 30, 2000

By 

Xingzhi Tan (USA) - See all my reviews
(REAL NAME)   

This review is from: DNA Repair Protocols (Methods in Molecular Biology) (Plastic Comb)

Personally I think "DNA Repair Protocol: Eukaryotic Systems" is a great academic book based on my over ten years of research experiences in Genetic Toxicology. This book provides detailed, step-by-step instructions for studying manifold aspects of the eukaryotic responses to genotoxic damage, including a lot of useful tips in handling all kinds of DNA repair experiments. Compared with Friedberg's textbook "DNA Repair and Mutagenesis", which comprehensively covers all fundamental knowledge about DNA damage, mutagenesis and DNA repair, this book focused on detailed experimental protocols and new techniques, plus a wonderful and concise introduction and explanation of each methods. In my opinion, this book refreshments my background knowledge, gives me an overview of recent progress in new methods and techniques, and ignites some new ideas to pursue further studies in this active field. Taken together, I think this is an essential handbook for professors and scientists in DNA damage and repair field and other related fields.