This important contribution to psychiatric literature, coming from a group of investigators who have developed a successful clinical research unit over the last decade, has the immediacy, clarity, and practicality expected from those who have personally wrestled with the difficult issues of design and data analysis. In addition, it draws upon a number of pioneers who have devised methods now used broadly in treatment research in psychiatry. This amalgam presents a very informative, down to earth and readable methods book, that should become the standard text in this growing field of investigation. The volume is divided into four sections: general issues, epidemiology, clinical studies, and psychopharmacology. The material offered in the book serves both as a review for clinical researchers and as a guide to clinicians to facilitate exploration in the fields of psychopathology and treatment. The path from clinical empiricism to scientific process ultimately leads to increased professional gratification and enhanced patient care.
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