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Rotavirus: Methods & Protocols (Methods in Molecular Medicine)
 
 
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Rotavirus: Methods & Protocols (Methods in Molecular Medicine) [Hardcover]

James Gray (Editor), Ulrich Desselberger (Editor)

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Book Description

0896037363 978-0896037366 February 15, 2000 1st
James Gray and Ulrich Desselberger have assembled a comprehensive collection of established and cutting-edge methods for studying and illuminating the structure, molecular biology, pathogenesis, epidemiology, and prevention in animal models of infection with rotaviruses, an important cause of infant morbidity and mortality. Presented by experts in the fields of animal and human rotavirus infections and rotavirus vaccine research, these readily reproducible methods detail molecular and other modern techniques, and include relevant background information and various notes to ensure reproducible and robust results. Authoritative and up-to-date, Rotaviruses: Methods and Protocols offers researchers today's benchmark compendium of experimental methods for the investigation of this medically significant virus.

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Editorial Reviews

Review

"This book will be very useful to both new investigators in the field and persons who have a general interest in rotaviruses and the methods to be used in their study. Many chapter contributors also provide very useful summaries of the methods used in a specific aspect of rotavirus research. These will be helpful to even the most experienced investigator in the field. "-Doody's Health Sciences Book Review Journal "This book has no recent equivalent....The book will not only be profitable for the RV specialist; people interested in other viruses or cellular physiology will surely benefit from the lessons learned from studies of RV electron cryomicroscopy, RV replication or animal models of RV infections." - Trends in Microbiology "...methods, which have proven invaluable to studies, are given in detail in this excellent new book. The contributors have written detailed protocols for, predominantly, molecular and serological methods with emphases on those that are somewhat unique to rotavirus research....However, there is much more to this book than the highly detailed protocols....The last of the central chapters is by Mary Ramsay and David Brown and describes the epidemiology of rotavirus infections and concentrates on surveillance and disease burden. Anyone still unconvinced of the need for a rotavirus vaccine should read this chapter."-J. Med. Microbiol "This high quality compendium comprises 12 concise chapters, each presented in the same easy to follow layout....this book at $89.50 is reasonable value and an essential reference for any laboratory undertaking rotavirus research."- Microbiology Today

From the Back Cover

In Rotaviruses: Methods and Protocols, James Gray and Ulrich Desselberger have assembled a comprehensive collection of established and cutting-edge methods for studying and illuminating the structure, molecular biology, pathogenesis, epidemiology, and prevention in animal models of infection with rotaviruses, an important cause of infant morbidity and mortality. Presented by experts in the fields of animal and human rotavirus infections and rotavirus vaccine research, these readily reproducible methods detail molecular and other modern techniques, and include relevant background information and various notes to ensure reproducible and robust results. Authoritative and up-to-date, Rotaviruses: Methods and Protocols offers researchers today's benchmark compendium of experimental methods for the investigation of this medically significant virus.

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Inside This Book (learn more)
First Sentence:
Rotaviruses (RVs) are the chief etiologic agent of viral gastroenteritis in infants and young children, and in the young of a large variety of animal species. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
virus control wells, interference phenotype, virus mixes, immunodepletion studies, gnotobiotic pigs, rotavirus infectivity, immunodeficient strains, reassortant vaccine, rotavirus disease, reassortant rotavirus vaccine, end point titer, outer capsid proteins, guanylyltransferase activity, combination anesthesia, human rotaviruses, parental viruses, adult mouse model, rotavirus infection, reassortant viruses, icosahedral lattice, rotavirus strains, fivefold axes, capsid layer, simian rotavirus, rotavirus serotypes
Key Phrases - Capitalized Phrases (CAPs): (learn more)
United States, Acta Paediatr, Humana Press Inc, Molecular Medicine, New York, Fields Virology, Irvine Scientific, Life Technologies, Oxford University Press, Spin Filter, Component Volume, San Diego, World Health Organization, International Classification of Diseases, Marcel Dekker, Santa Ana, Structural Biology of Viruses, Viral Infections of the Gastrointestinal Tract, Virus Res
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