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SLN microscopic melanoma may lower survival: any patient with sentinel lymph node evidence of metastatic melanoma may be at risk for ... An article from: Skin & Allergy News [HTML] [Digital]

Damian McNamara

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PALM BEACH, FLA. -- The presence of microscopic or even submicroscopic melanoma in a sentinel lymph node may be clinically relevant, a retrospective study has shown.

"We believe patients with microscopic deposits of metastatic melanoma have biologically relevant, potentially life-threatening disease," Dr. David W. Ollila said at the annual meeting of the Southern Surgical Association.

Although other investigators have proposed that submicroscopic disease (a sentinel node tumor that is less than 0.1 mm) is not associated with a significantly increased risk of recurrence or death (Br. J. Surg. 2007;94:1293-9), Dr. Ollila and his associates hypothesized that any sentinel node evidence of metastatic melanoma, regardless of size or stage, may be a cause for concern.

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