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Sam-e 400 400 mg 30 Tabs

from Jarrow
4.5 out of 5 stars 19 customer reviews
About the Product
  • Supports mood and brain function
  • Helps detoxify the liver
  • Promotes healthy connective tissue

Frequently Bought Together

  • Sam-e 400 400 mg 30 Tabs
  • +
  • Jarrow Formulas Methylcobalamin (Methyl B12), Supports Brain Cells, 5000 mcg, 60 Lozenges
Total price: $41.13
Buy the selected items together

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Product Description

SAM-e (S-Adenosylmethionine) is an amino acid derivative that has undergone dozens of trials involving thousands of patients and has been clinically proven to benefit brain and joint function. Found in all living cells, SAM-e is also called activated methionine (an essential amino acid) since it is formed by the combining of ATP with methionine. SAM-e 400 is manufactured under low temperature and low humidity and is enteric-coated to ensure a biologically active product. It is made naturally by microbiological fermentation and then specially processed to preserve 68-80% (S,S) SAM-e, the highest active level available.

Product Details

  • Item Weight: 2.1 ounces
  • Shipping Weight: 0.3 ounces (View shipping rates and policies)
  • ASIN: B00125ZA5M
  • UPC: 790011200208
  • Item model number: 6953
  • Average Customer Review: 4.5 out of 5 stars  See all reviews (19 customer reviews)
  • Amazon Best Sellers Rank: #53,115 in Health & Personal Care (See Top 100 in Health & Personal Care)

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Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Please see our full disclaimer below.

Customer Reviews

Top Customer Reviews

Verified Purchase
My doctor recommended this because I have some neurotransmitter issues. IDK what they are, but he said SAM-e would even them out. Or get rid of the extra. Anyway, I've been on it 3 weeks and I think it's working. I haven't lost my sh*t in a couple weeks. And it gives me a good boost of energy. I would try it for a few weeks to see if you feel any different.
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I had issues of depression after baby, and severe joint pain. So I took this sam e for 3 months and feel such a difference for the better. Within the first 2 weeks the depression was lifting and the joint pain was greatly improved if not gone. I have tried going off of this a couple of times and need to continue on this I have figured out. Without this product I know I would have to be on prescription anti depressants and I wanted to avoid that. It has given me no side effects, except occasional stomach pains. Nothing that keeps me from going about my daily activity but everyone is different. It has really given me my life back and for that I am thankful.
Just know that you need to take this for 3 months to get it in your system to know if it is really helping. You should know by then.
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I was suffering from severe anxiety. I had some high stress incidents and i didn't bounce back. It was pretty horrible. I tried acupuncture and various forms of energy work and counseling. Those thing helped some, but I beleive that the SAM-e is the one thing that stabilized my brain.

The bad part is that no one suggested it and I spent a ton of money and suffered for months until i took it upon myself to try SAM-e. I had taken it a few years ago for depression. I had a hunch that it might help my anxiety and I was right!

Also, I started taking Lugol's iodine a few weeks ago and it has helped lift my mood and given me so much more energy!

Too many people are suffering with anxiety and depression.
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By kat on September 3, 2013
Verified Purchase
Excellent product. This manufacturer is well regarded and the product does work for joints and depression. Easy to use. Highly recommend.
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This product is very high in quality and
is way more potent than Nature Made
Sam-e,and less expensive.I highly recommend it.
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Verified Purchase
I have used Amazon for almost 10 years and I've never written a review because I'm just not the type to do so, nor do I have the time or energy to put in the effort. However, I am so amazed with this product, I have a burning desire to share my positive experience.

First of all, I have tried EVERYTHING to help depression. Seriously. I've always experienced prescription drugs to be too much for my system no matter the dosing and the time I waiting the side effect out. With Sam-e, I started out taking 400s right as I woke up. (30 min before breakfast.) The first 5-6 days, I experienced heightened anxiety and insomnia. I remember one night just wide eyed thinking that it was ridiculous that I couldn't sleep. After about 5-6 days, I started to sleep normal again and the anxiety tapered off. Before I even realized it, I was just level. It's hard to explain. The edge was taken off. I've been really stressed out and depressed, and I'm in my second year of nursing school. Now, 2 months on Sam-e, the stress is minimal because I am able to control my perception on situations and life so much better. Control is something I've never had with my emotions or mental being. I've struggled with a little OCD, depression to where I wouldn't leave the house, sometimes not get out of bed and I would sit in my car for hours because I just felt like I couldn't move. I wouldn't even go into a grocery store because I didn't feel confident to deal with people or strangers. Sam-e has saved my life! That sounds so cliché but I am being as authentic as I can here. I don't feel like I'm on anything and I have zero side effects. I've not felt like I needed to adjust my dosing, as some people feel they need to bump up to higher doses to feel more of an affect.
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Verified Purchase
I am using this product on my 13 year old Sheltie. Her symptoms have improved dramatically since I started her on this product. She has old age liver disease and if this product keeps her around longer, then it is great.
She has shown remarkable signs of getting back to her old self since she has been taking it.
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Verified Purchase
I've taken this for four months now and it has really helped my depression. I take 400mg once a day. I thought after a couple months when I got to feeling better, that I'd go off but could feel the depression coming back within a week or so. I talked to my dr who approved of it and advised I stay on it a year. He said anything that is natural vs. a prescribed chemical is so much better for you. I'm also a runner so I feel the part about strengthening your joints is also beneficial for me. The only con is that I have to pay for it and if it was prescription, my insurance would cover it but want to go with what's better for me. Knowing I have to take for a year, I subscribed to it on Amazon so that gives a little discount. I take B vitamins along with it as I read that it helps deliver it through your system. I don't know, figure it doesn't hurt to take the vitamins anyway! Highly recommend as I've been on anti-depresants off and on thru the years and did not care for that "fakey" feeling. This does not do that!
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