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The Science of Desire: The Search for the Gay Gene and the Biology of Behavior
 
 
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The Science of Desire: The Search for the Gay Gene and the Biology of Behavior [Paperback]

Dean Hamer (Author), Peter Copeland (Author)
4.0 out of 5 stars  See all reviews (4 customer reviews)

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Book Description

December 14, 1995
In July 1993, a scientific event made front-page news: the discovery that genetics plays a significant role in determining homosexuality. In The Science of Desire, Dean Hamer -- the scientist behind the groundbreaking study -- tells the inside story of how the discovery was made and what it means, not only for our understanding of sexuality, but for human behavior in general.

In this accessible and remarkably clear book, Dean Hamer expands on the account of his history-making research to explore the scientific, social, and ethical issues raised by his findings. Dr. Hamer addresses such tough questions as whether it would be possible or ethical to test in utero for the gay gene; whether genetic manipulation could or should be used to alter a person's sexuality; and how a gay gene could have survived evolution.

A compelling behind-the-scenes look at cutting-edge scientific inquiry, as well as a brilliant examination of the ramifications of genetic research, The Science of Desire is a lasting resource in the increasingly significant debate over the role that genetics plays in our lives.


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Editorial Reviews

From Publishers Weekly

A chronicle of the scientific investigation through which Hamer, a researcher at the National Cancer Institute, came to the controversial conclusion that he had discovered the "gay gene."
Copyright 1995 Reed Business Information, Inc.

From Library Journal

After reading books by Charles Darwin and Richard Lewontin, Hamer (a yeast geneticist at the National Cancer Institute) discovered that little is known about behavioral genetics in humans. He was intrigued enough to change his research direction. This book is a personalized account of the luck, pleasures, and pitfalls involved in scientific investigation-from the germ of an idea about genetic markers for homosexuality to results suggesting that the X-chromosome carries a marker for male homosexuality and speculation on the evolutionary and physiological mechanisms involved. Hamer's research included an intimate exploration of the development of homosexual behavior, family histories, and, finally, careful statistical and molecular analysis. Fortunately for Hamer, he already occupied a prestigious position that covered his day-to-day laboratory needs since the path he chose had many barriers, including hostility from celebrated scientists and intense public attention. While the topic may be offensive to some, this is an engaging odyssey through the mind of a scientist on a controversial path, with much musing, justification, and reassessment along the way. Recommended for both lay readers and specialists.
Constance Rinaldo, Dartmouth Coll., Hanover, N.H.
Copyright 1994 Reed Business Information, Inc. --This text refers to an out of print or unavailable edition of this title.

Product Details

  • Paperback: 272 pages
  • Publisher: Touchstone (December 14, 1995)
  • Language: English
  • ISBN-10: 0684804468
  • ISBN-13: 978-0684804460
  • Product Dimensions: 8.9 x 6 x 0.8 inches
  • Shipping Weight: 14.9 ounces (View shipping rates and policies)
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (4 customer reviews)
  • Amazon Best Sellers Rank: #333,684 in Books (See Top 100 in Books)

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19 of 20 people found the following review helpful:
5.0 out of 5 stars Excellent lay description of one search for a gay gene, July 6, 1997
By A Customer
This review is from: The Science of Desire: The Search for the Gay Gene and the Biology of Behavior (Paperback)
I very much enjoyed reading this book and learned a lot from it both about the way in which these particular researchers are going about their work and about genetics in general.

Hamer is the Chief of the Section on Gene Structure and Regulation in the Department of Biochemistry at the National Cancer Institute. This book describes in lay terms the work that led to the publication of the scientific paper entitled "A Linkage Between DNA Markers on the X Chromosome and Male Sexual Orientation". The goal of the study was to determine whether male sexual orientation was "genetically influenced" and what they found was "a statistically significant correlation between the inheritance of genetic markers on chromosomal region Xq28 and sexual orientation in a selected group of homosexual males." The statistical significance was strong: the odds of the correlation happening by chance was only 1 out of 100,000.

Before they started looking at genes, Hamer and his group considered the family histories of the pairs of gay brothers who he used in his study. The researchers found more gay men on the maternal side and eventually realized that this was due to recessive X-linked inheritance. "X-linked traits always are passed to men through the mother's side of the family, which is the pattern we were seeing for homosexuality."

The book carefully explains how the research was done and what conclusions could and could not be drawn from it. They did not find a gay gene; they only showed that one exists. It does not "determine" homosexuality; it is only one factor in the makeup of those gay men who inherited it. There may be other genes that play a role and there are surely many environmental factors that influence the expression of homosexuality. Some of the evidence from Hamer's study "suggests that Xq28 plays some role in about 5 to 30 percent of gay men."

The book closes with a chapter on the social implications of this research. There is also an interesting chapter addressing the question "How could a gay gene survive consistent with the facts of evolution?"

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3 of 5 people found the following review helpful:
5.0 out of 5 stars Getting your money's worth, August 9, 2003
By 
Arthur V. Dieli (Sacramento, CA United States) - See all my reviews
(REAL NAME)   
Dean Hamer, the scientist, and Peter Copeland, the writer have produced an informative entre to the complex world of the genome for the general reader. They've done the job in a very interesting but measured manner. While the book is dated, it is not outdated.
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5 of 9 people found the following review helpful:
5.0 out of 5 stars Bloody brilliant book, September 23, 1998
By 
peja@xtra.co.nz (Auckland New Zealand) - See all my reviews
A really good piece of scientific writing that is not only good, well researched science, but is also well written. Dean Hamer has proved something that I'd already known since I was knee high to a grasshopper, but its good to see proof for those who dont already know this from personal experience.
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Inside This Book (learn more)
First Sentence:
Every single day, in laboratories and universities, scientists make discoveries, some great and some small, but few of them are reported on the front pages of the world's major newspapers, featured on talk shows, included in Time magazine's list of "The Best Science" of the year, heralded in the National Enquirer, and turned into catchy slogans for T-shirts. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
thru aunt, thru uncle, two gay brothers, gay male subjects, gay gene, gay relatives, multipoint mapping, female sexual orientation, heterosexual brothers, first sexual contact, lod score, homosexual brothers, gay version, family enrichment, gay subjects, androgen receptor gene, discordant pairs, other sexual activities, maternal cousins, background rate, gay fathers
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Human Genome Project, Cancer Institute, New York, United States, Harvard University, Angela Pattatucci, Cousin Martin, Elliot Gershon, National Institutes of Health, Roger Gorski, Ruth Hubbard, Juanita Eldridge, Michael Bailey, Triangle Club
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