First Sentence:
One may consider at least four major questions about the epidemiology of Down's syndrome that are pertinent directly or indirectly to biochemical screening and prevention.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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beta human choriogonadotropin, serum biochemical indicators, maternal serum chorionic gonadotropin levels, triple analyte screening, gestation dating, human chorionic gonadotropin screening, maternal serum chorionic gonadotrophin, estimated detection rate, human chorionic gonadotropin free subunits, first trimester biochemical screening, gonadotropin fragment, fetal chromosomal disorders, uncultured amniotic fluid samples, women carrying male fetuses, adjustment for maternal weight, trophoblast disease, maternal serum human chorionic gonadotrophin, fetal chromosome abnormalities, syndrome screening, routine ultrasound scan determination, maternal serum unconjugated oestriol, conventional chromosome analysis, maternal serum markers, maternal serum screening, unaffected pregnancies
Key Phrases - Capitalized Phrases (CAPs):
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Prenatal Diagn, New York, Genetic Disease Branch, University Hospital, Churchill Livingstone, United Kingdom, Academic Press, Milford Ward, Royal College of Physicians, Acta Obstet, Black Report, Plenum Press, Association of Clinical Biochemists, Cancer Res, Fetal Diagn, Integrated Genetics, Likelihood Ratio Fig, References Aitken, Ultrasound Med, United States, University of Tennessee, Acta Endocrino, American Society of Human Genetics, Clinical Genetics Society, Northern Ireland
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