Rue Heirloom Medicinal 4-5-feet. Hardy Perennial Dense, fragrant foliage and pretty yellow flowers make for a attractive border on an 18-24-inch plant. Older European culinary and medicinal herbal stated its use for the relief of nervous disorders, cramps, and irregular menstruation. (Handling it fresh causes dermatitis for some. Do not use during pregnancy.) Zones 5-9. Planting Depth: 1/4-inch Soil Temp. for Germ: 70-Degree F, day to Germ: 7-10 Plant Spacing: 8-12-inch, day to Maturity: 60 Partial Shade Water Less, Drought Tolerant