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Selective Sentinel Lymphadenectomy for Human Solid Cancer (Cancer Treatment and Research)
 
 
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Selective Sentinel Lymphadenectomy for Human Solid Cancer (Cancer Treatment and Research) [Hardcover]

Stanley P. L. Leong (Editor), Yuko Kitagawa (Editor), Masaki Kitajima (Editor)

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Book Description

March 21, 2005 Cancer Treatment and Research (Book 127)
First book to apply the concept of SSL to the majority of human cancers Revolutionary new concept that might significantly transform surgical cancer treatment Focuses on cancer metastasis and explores the biological frontier of micro metastasis Includes illustrations by experts in the field on how to successfully perform SSL

Editorial Reviews

Review

From the reviews: "This is a current comprehensive book on sentinel lymphadenectomy … . The book is written for the surgeon … . This includes residents in training, surgical oncology fellows, and practicing surgeons. The written detail, supporting diagrams, and pictures provide a complete practice manual. … A single book that contains 10 years of journal material is convenient and for those not following the literature invaluable. … no other book has united several different diseases and explored them through the SLN concept." (Neal Wilkinson, Doody's Electronic Journal, May, 2005)

From the Back Cover

Lymph node (LN) status is the most important prognostic indicator for the clinical outcome of patients in human solid cancer. Recent developments in sentinel lymph node (SLN) concept and technology have resulted in the application of this revolutionary approach to determine if cancer has metastasized. The underlying thesis in solid cancer biology is that metastasis generally starts in an orderly progression, often spreading through the lymphatic channels to the SLN. Thus, the logical approach is to harvest that specific SLN for thorough analysis. The most exciting possibility of selective sentinel lymphadenectomy (SSL) is that it will lead to early diagnosis of micrometastasis in regional LNs. Early diagnosis makes it useful as a clinical staging procedure, and opens up new opportunities to study micrometastasis and its evolution within the SLNs. New molecular and genetic tools may be used to dissect the mechanisms of lymphatic and hemotogenous routes of metastasis. If such mechanisms can be understood, new therapeutic advances may be developed to prevent the process of micrometastasis. *********************************************************************************** Minimally invasive surgery associated with reduced morbidity has transformed the management of cancer patients. Sentinel lymphadenectomy for staging and treatment of solid tumors is now standard of care in many settings. In this text, distinguished investigators review the technical aspects and clinical considerations related to this procedure. Steven T. Rosen, M.D. Series Editor

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Inside This Book (learn more)
First Sentence:
Intraoperative lymphatic mapping and sentinel lymphadenectomy (ILM/SL) is a novel surgical technique that has substantially impacted on the way cutaneous melanoma and breast cancer are now being staged and managed. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
micrometastatic melanoma, small particle radiocolloids, draining lymph node station, lymphogenic metastatic spread, selective sentinel lymphadenectomy, resection bed count, wide local reexcision, second tier nodes, occult melanoma cells, radiocolloid particles, preoperative lymphoscintigraphy, harboring metastatic disease, basin dissection, sentinel node concept, lymphatic mapping, human solid cancer, sentinel lymphadenectomy for breast cancer, selective sentinel lymph node dissection, complete axillary lymph node dissection, occult tumor cells, preoperative lymphoscintigram, primary melanoma site, sentinel node identification, lymphatic collecting vessel, blue lymph node
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Annals of Surgical Oncology, Nucl Med, Clin Oncol, Cancer Res, Ann Surg Oncol, Annals of Surgery, Arch Surg, Head Neck, United States, Gynecol Oncol, Journal of Clinical Oncology, New York, Obstet Gynecol, Multicenter Selective Lymphadenectomy Trial, Surg Pathol, Archives of Surgery, The Surgical Clinics of North America, American Joint Committee, Clin Pathol, Gynecologic Oncology Group, John Wayne Cancer Institute, Martin Dunitz, American Journal of Surgery, Arch Pathol Lab Med, Archives of Dermatology
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