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Solgar Folate 800 mcg (as Metafolin)- 100 Tablets

from Solgar
142 customer reviews
| 6 answered questions

About the Product

  • Solgar

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  • Solgar Folate 800 mcg (as Metafolin)- 100 Tablets
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Product Description


Folate 800 mcg (as Metafolin) by Solgar 100 Tablet Folate 800 mcg (as Metafolin) 100 Tablet Product Folic Acid must first be converted to its active form by a series of biochemical steps before it is able to be used by the body. Metafolin (L-methylfolate) requires no conversion because it is bioidentical to the bio-active form. In other words it is body-ready. This can be useful for individuals whose bodies have difficulty converting folic acid to its active form. The active folate in this formulation promotes heart health. It also supports a healthy nervous system and the formation of healthy red blood cells. Suggested Use As a dietary supplement adults take one (1) tablet daily preferably at mealtime - Or as directed by your healthcare professional. Supplement Facts Serving Size 1 Tablet Servings Per Container 100 Amount Per Serving Daily Value Folate (as L-methylfolate-Metafolin) 800 mcg 200 Percent Daily Values are based on a 2 000 calorie diet Other Ingredients Mannitol Microcrys

Product Details

Size: 100
  • Product Dimensions: 4.2 x 2.3 x 2.3 inches
  • Shipping Weight: 3.5 ounces (View shipping rates and policies)
  • ASIN: B001LR2RVQ
  • UPC: 033984019454
  • Item model number: 033984019454
  • Average Customer Review: 4.7 out of 5 stars  See all reviews (142 customer reviews)
  • Amazon Best Sellers Rank: #1,878 in Health & Personal Care (See Top 100 in Health & Personal Care)
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Actual product packaging and materials may contain more and different information than what is shown on our website. We recommend that you do not rely solely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. Please see our full disclaimer below.

Customer Questions & Answers

Customer Reviews

Most Helpful Customer Reviews

350 of 362 people found the following review helpful By W. R. Russell Jr. on January 31, 2012
Size: 100 Verified Purchase
If you're one of the 40 - 60% of people that have some form of defect in one or both of the genes responsible for methylation (MTHFR polymorphism) and you want to try and bypass that blockage to get your methylation system back up to speed, then Metafolin (aka: 5-methyltetrahydrofolate, 5-MTHF, levomefolic acid, or l-methylfolate) is a vital part of the protocol. This is the form ultimately used by the body. If you're an ineffective methylator, it's also the one that works, because your body doesn't have to convert it further to be useful. If you're of caucasian, hispanic, or Mediterranean descent, or have a high IQ, your odds are higher.

This version (Metafolin) is the OTC strength (800 mcg) of the prescription Deplin (7.5 mg), but both are essentially the fully reduced (by methylation - what else) version of folate that the body actually uses...there are a number of enzyme mediated steps in converting folic acid and folates to the useable methylated form. It is also the only one that will cross the blood-brain barrier. Merck apparently figured out how to do the same thing and came up with a bioidentical form...and then patented their process for making it. I'm sure they knew about the distribution of the polymorphism and how big the market would be. I'm a business major, not a doctor. Props to Merck here, not slams.

This is one of the few times that I think a pharmaceutical company may have gotten it right and should serve as a lesson to the others...vitamins and minerals in their most useable forms are curative medicines...curative...they cure diseases...not just treat them. Name one man made synthetic drug, not based on copying a biological compound, that has that claim.
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40 of 42 people found the following review helpful By bambam on August 14, 2013
Size: 100 Verified Purchase
Yes I have the MTHFR 677CT mutation (heterozygous) and have been taking Deplin since it first came out in 2008. I have tried other brands and nothing came close to working like Solgar's Folate. As time has gone I have been able to switch to Solgar Brand, and have reduced the deplin to 7.5mg and some days only take the Solgar 2X a day. I have researched Folate over the last five years and found that I respond better to Metafolin and to other forms of active folate sold over the counter, why I don't know and really don't care...Try this if you are looking for a cheaper alternative to Deplin, maybe you will repond like I have. Nothing short of a miracle.....
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40 of 44 people found the following review helpful By Dr JAS Spiegel VINE VOICE on July 26, 2012
Size: 100 Verified Purchase
I have a Folate variation, and have to take a prescription Folate L-Methylfolate. The L-Methylfolate in the Solgar product is called Metafolin. (just a quick mention... folic acid isn't the same. I didn't know that before.).

The Solgar Folate is the only Folate I've taken that gives me a boost in the afternoon, when I'm starting to feel like I need a shot of B-12, or "I coulda used a V-8!", or a Red Bull... do you ever have that feeling where you really feel wilted?! I've found a couple of things that seem to really help, the Solgar Folate 800 mg. I'm trying a couple of new products and will review those after I've had a chance to give them a try.

The taste isn't bad, you can even chew them if you want. It has a bit of a sugary, but powdery taste - so you might want to follow it up with a sip of something. The bottle does say the product "provides an insignificant amount of sugar alcohols - if there are any people who need that information. The size is about the size of a regular Tylenol tablet - not at all difficult to swallow if you go that route .. instead of chewing! And it's "free of gluten, wheat, dairy, soy, yeast, sugar, sodium, and artificial colors and flavors".

As of the time I purchased there was not a subscription for this particular product, but I will continue to purchase as it is the best product at the most reasonable price that I have found!

Solgar - Folate (Metafolin)800 Mcg, 100 tablets

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29 of 33 people found the following review helpful By D&D TOP 500 REVIEWER on June 30, 2014
Size: 100
The proper, active form is folate (vitamin B9), the only form that can cross the blood-brain barrier and enter the brain. Also, many people cannot convert folic acid supplements to folate, so make sure to buy only folate supplements like this one, metafolin, which is methyltetrahydrofolic acid or L-methylfolate. It's shocking that millions of pregnant women are advised to take folic acid, which is synthetic. Research shows it can cause cancer!

As Dr Mark Hyman warns: "Man-made molecules do funny, unpredictable things because they don't work with our normal biochemical pathways. Nature made molecules we have consumed for millennia work with our bodies. Folic acid, the molecule that is used to fortify our food supply, is used in most studies and in most vitamins. It is a man-made, funny looking molecule - a fully oxidized, synthetic chemical compound that seems to cause [more] mischief [than good]. It costs less and is more stable than the nature-made form of this nutrient.

"On the other hand, the nature-made form or forms, called "folates," do not seem to cause problems. This molecule is often found in foliage - dark green leafy vegetables, hence the name folate. This can enter your normal biochemical pathways and gets properly metabolized. The folic acid may not be converted or metabolized by the body, increasing cancer and disease risk. The excess folic acid becomes oxidized and promotes free radical production and genetic instability leading to cancer and other disease.

"The nature-made form of this nutrient - called methyl folate (and there are a few forms of that too) - is what should be in food and vitamin supplements. Many conscientious companies are now using only this form of the nutrient, but it is more expensive.
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Want to discover more products? Check out these pages to see more: nature active dietary supplements, vitaminlife solgar, vitamin b9, solgar folic acid

Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. assumes no liability for inaccuracies or misstatements about products.