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Splendid Solution: Jonas Salk and the Conquest of Polio
 
 
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Splendid Solution: Jonas Salk and the Conquest of Polio [Hardcover]

Jeffrey Kluger (Author)
4.2 out of 5 stars  See all reviews (18 customer reviews)


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Book Description

0399152164 978-0399152160 January 27, 2005 1
The riveting story of one of the greatest scientific accomplishments of the twentieth century, from the coauthor of the #1 New York Times bestseller Apollo 13.

With rivalries, reversals, and a race against time, the struggle to eradicate polio is one of the great tales of modern history. It begins with the birth of Jonas Salk, shortly before one of the worst polio epidemics in United States history. At the time, the disease was a terrifying enigma: striking from out of nowhere, it afflicted tens of thousands of children in this country each year and left them-literally overnight-paralyzed, and sometimes at death's door.

Salk was in medical school just as a president crippled by the disease, Franklin D. Roosevelt, was taking office-and providing the impetus to the drive for studies on polio. By the early 1950s, Salk had already helped create an influenza vaccine, and was hot on the trail of the polio virus. He was nearly thwarted, though, by the politics of medicine and by a rival researcher eager to discredit his proposed solution. Meanwhile, in 1952, polio was spreading in record numbers, with 57,000 cases in the United States that summer alone.

In early 1954, Salk was weighing the possibility of trials of a not-yet-perfected vaccine against-as the summer approached-the prospect of thousands more children being struck down by the disease. The results of the history-making trials were announced at a press conference on April 12, 1955: "The vaccine works." The room-and an entire nation-erupted in cheers for this singular medical achievement.

Salk became a cultural hero and icon for a whole generation. Now, at the fiftieth anniversary of the first national vaccination program-and as humanity is tantalizingly close to eradicating polio worldwide-comes this unforgettable chronicle. Salk's work was an unparalleled achievement-and it makes for a magnificent read.

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Editorial Reviews

From Publishers Weekly

Starred Review. For children today, the word "polio" means little more than a series of shots, a mundane part of health care. Fifty years ago, however, polio was a dark shadow that arrived every summer, a deep fear hanging over every child and parent. Every year, the disease left tens of thousands of children crippled, paralyzed or, worse, reliant on an iron lung to aid them in breathing. Time magazine senior writer Kluger, coauthor of the bestselling book that was the basis for the movie Apollo 13, tells how polio was beaten 50 years ago in one of the triumphs of modern medicine. The narrative naturally centers on Jonas Salk, whose lab developed the first polio vaccine, but this is by no means a simple biography. Kluger is best when describing science as a team enterprise, and this account offers a keen understanding of the vast machine of people and resources mobilized to combat polio. The book is well researched and accessible, made all the more tense and gripping by the author's depiction of the pre-vaccine world—by describing what it was like to live in fear of polio, Kluger reminds us how joyous and heroic an event its conquest was. B&w photos not seen by PW.
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

From Booklist

*Starred Review* Kluger begins his riveting account of the battle against the viral crippler in 1916, with Dora Salk worrying about her infant son's susceptibility during the first severe polio epidemic. Jonas Salk became not a victim but the slayer of polio, though Franklin D. Roosevelt's disabling 1921 bout with the virus and his inspiration of the National Foundation for Infantile Paralysis were crucial to Salk's realization of one of modern medicine's finest achievements. Roosevelt's subsequent prestige as president powered the NFIP's fund-raising juggernaut, and its gleanings funded the long process of finding a safe, effective vaccine, including Salk's Pittsburgh labs. From early on, researchers fiercely debated the respective merits of live-virus and killed-virus vaccines. Salk, who had already helped make the flu vaccine, advocated killed-virus vaccine, considering the risk of contracting polio from its ostensible prophylactic--never completely avoidable with any live virus, however weakened--intolerable. Of course, Salk succeeded, but shortly after, so did his principal live-virus opponent, Albert Sabin. Such is the plotline that Kluger masterfully fills out with sketches of the many players, crossroads incidents, and scientific politicking (in which Sabin definitely comes out smelling other than rosy) in the intense search for the weapon that would kill polio. Can't-put-it-down medical-science history. Ray Olson
Copyright © American Library Association. All rights reserved

Product Details

  • Hardcover: 384 pages
  • Publisher: Putnam Adult; 1 edition (January 27, 2005)
  • Language: English
  • ISBN-10: 0399152164
  • ISBN-13: 978-0399152160
  • Product Dimensions: 9.1 x 6.2 x 1.5 inches
  • Shipping Weight: 1.3 pounds
  • Average Customer Review: 4.2 out of 5 stars  See all reviews (18 customer reviews)
  • Amazon Best Sellers Rank: #1,519,457 in Books (See Top 100 in Books)

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Customer Reviews

18 Reviews
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Average Customer Review
4.2 out of 5 stars (18 customer reviews)
 
 
 
 
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8 of 8 people found the following review helpful:
5.0 out of 5 stars Thrilling Medical Tale, February 2, 2005
By 
Rick (Manchester) - See all my reviews
This review is from: Splendid Solution: Jonas Salk and the Conquest of Polio (Hardcover)
This is wonderfully compelling story of the race to cure polio, a disease that--if you're old enough to remember--lingered in the minds of terrified mothers and children everywhere fifty years ago. It also offers an indepth look into the life of Jonas Salk, a fascinating man whose drive to cure this disease was remarkable. Well-told, exciting--tough to put down. For fans of the The Great Influenza and The Greatest Generation.
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11 of 13 people found the following review helpful:
5.0 out of 5 stars Compelling Read - Gripping, fascinating and powerful, February 22, 2005
By 
This review is from: Splendid Solution: Jonas Salk and the Conquest of Polio (Hardcover)
"Splendid Solution" is a splendid book. From the opening page, the reader is swept into the world of Jonas Salk and the race to find a vaccine to prevent polio.

If you're a baby boomer, you'll remember getting the Salk or Sabin vaccine -- and marvel that our largest generation of children were protected by the efforts of Dr. Salk and his research team. If you're a parent of a baby boomer, you'll relive the horrors of summers in the 30s, 40s and 50s when the scourge of polio raced through the nation - striking at every level of society - even a future president - FDR.

Like "THE HOT ZONE" -- this is a riveting read! Highly recommended!
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4 of 4 people found the following review helpful:
5.0 out of 5 stars The politics of science, October 14, 2008
By 
M. Strong (Milwaukee, WI USA) - See all my reviews
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On page 318 of this book, Jonas Salk is quoted as saying, "When you're arguing for an unpopular idea, there are three stages of truth. First, your opponents say it can't be true. Next they say if it's true, it can't be very important. Finally they say well, we've known it all along." To me, Splendid Solution does an excellent job of telling the story of Salk arguing for his unpopular idea, the eventually successful Salk vaccine.

To me as on outsider, the world of science seems like it should be very fact-based and black and white. The more I read about the history of science, however, the more I learn how far that is from the truth. Some reviews complain this book doesn't have enough of the science of vaccination or epidemiology, but I think Kluger's decision to focus his story specifically on the politics of gaining acceptance within the scientific community for a brilliant idea makes a great book.

Kluger lays out the entire process of funding, scientific conferences, personality conflicts and personal hierarchy within scientific circles. It's brilliant in that it shows both the strengths and the weaknesses of the system. Further, I found reading the book caused me to take stock of my own preconceived notions and thought processes to think about what great new ideas I might be ignoring because they didn't fit my own preconceived notions.

A great book for anyone who is interested in understanding a little more about what goes on behind the scenes in scientific circles, or who would like to understand the process by which the Salk vaccine was vetted and developed.
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Inside This Book (learn more)
First Sentence:
There was a time when a black car with lacquered doors would not have attracted much attention on East 106th Street-but that was before the cars started coming to take the babies away. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
virus lab, polio work, polio season, polio problem, clip service, polio ward, polio research, typing work, polio cases, author conversations, infantile paralysis, poliomyelitis vaccine, typing program, foundation chief, killed vaccine, author interview
Key Phrases - Capitalized Phrases (CAPs): (learn more)
New York, Jonas Salk, Basil O'Connor, Albert Sabin, United States, University of Pittsburgh, Tommy Francis, Warm Springs, John Troan, University of Michigan, Harry Weaver, Lorraine Friedman, Ann Arbor, Franklin Roosevelt, Municipal Hospital, Thomas Rivers, Rackham Hall, Allegheny County, March of Dimes, Rockefeller Institute, Camp Wellston, Elsie Ward, Pittsburgh Press, Public Health Service, Bill Kirkpatrick
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