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Stem Cells in Endocrinology (Contemporary Endocrinology)
 
 
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Stem Cells in Endocrinology (Contemporary Endocrinology) [Hardcover]

Linda B. Lester (Editor)

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Book Description

February 22, 2005 Contemporary Endocrinology
A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

Editorial Reviews

Review

From the reviews: "Stem Cells in Endocrinology considers the potential use of stem cells for the treatment of endocrine disorders. It consists of two sections, Basic Stem Cell Biology and Translational Research. … The book as a whole is certainly of interest not only to specialists in the therapy of endocrine disorders, but also to those conducting stem cell research in general, and to motivated students." (Antonin Bukovsky, TRENDS in Endocrinology and Metabolism, Vol. 17 (6), August, 2006)

From the Back Cover

Stem cell research can not only develop potential sources of cells for endocrine therapy, but can also allow the study of organ development ex vivo using isolated and defined stem cell precursors. In Stem Cells in Endocrinology, leading stem cell biologists and developmental endocrinologists critically review both cutting-edge approaches to stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders. Background chapters provide a basic understanding of stem cell biology and introduce all major types of stem cells, including embryonic, adult, cord blood, and germ line. State of the art and forward looking, Stem Cells in Endocrinology offers the basic and clinician scientist an authoritative evaluation of all aspects of how stem cells might be used to create endocrine cells and to treat such diseases as type 1 diabetes.

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Inside This Book (learn more)
First Sentence:
Stem cells, which have a great capacity for self-renewal and can differentiate into at least one committed cell type, exist in embryonic and adult organisms of many phyla. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
spermatogenic stem cells, endodermal stem cells, diffuse islet cells, male germ line stem cells, stem cell enrichment, sternness genes, umbilical cord matrix, recipient testes, mesenchvmal stem cells, fetal pancreatic cells, lineage stem cells, pancreatic stem cells, pancreatic differentiation, native islets, islet differentiation, umbilical cord blood cells, expanded ductal tissue, hone marrow stromal cells, stem cell activity, emhryoid bodies, hone regeneration, cultured human primordial germ cells, endocrine autoimmune diseases, stem cell niche, liver repopulation
Key Phrases - Capitalized Phrases (CAPs): (learn more)
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