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Strategies for Organic Drug Synthesis and Design
 
 
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Strategies for Organic Drug Synthesis and Design [Hardcover]

Daniel Lednicer (Author)
4.0 out of 5 stars  See all reviews (1 customer review)


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Hardcover, January 2, 1998 --  
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Strategies for Organic Drug Synthesis and Design Strategies for Organic Drug Synthesis and Design 4.0 out of 5 stars (1)
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Book Description

0471196576 978-0471196570 January 2, 1998 1
All of the breadth and depth of organic drug synthesis-in one resource

This work offers a clear examination of the synthetic routes followed to prepare a range of compounds with assigned generic names. With drugs selected for the illustrative value of the chemistry used for synthesis, the book illustrates a great variety of organic transformations and structural classes of compounds.

Ideal for anyone learning or working in organic, medicinal, or pharmaceutical chemistry today, Strategies for Organic Drug Synthesis and Design includes:
* Coverage of carbocyclic and heterocyclic compounds-steroids, opioid analgesics, beta lactam antibiotics, and more
* Hundreds of reaction flow charts detailing routes used to prepare over 600 compounds
* Biological rationales for drug classes and actions of individual agents
* Capsule presentations of basic principles of drug action
* An extensive chemical reaction index with over 3,000 entries.

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Editorial Reviews

Review

?In this book, Lednicer presents a detailed discussion of strategies toward the synthesis of pharmaceutical compounds. . . The strength of the book is the wealth of data collected in one relatively short tone?. --This text refers to an alternate Hardcover edition.

From the Publisher

The field of organic synthesis has influenced chemistry and in turn society in a profound number of areas, from the development of medicinal agents to an astonishing variety of polymers. This book focuses upon the strategies and organic transformations which have been used to prepare the various structural classes that have been investigated as drugs. Special attention is paid to clarifying individual reactions of the drugs, and the text includes an extensive "Reaction Index."

Product Details

  • Hardcover: 520 pages
  • Publisher: Wiley-Interscience; 1 edition (January 2, 1998)
  • Language: English
  • ISBN-10: 0471196576
  • ISBN-13: 978-0471196570
  • Product Dimensions: 9.6 x 6 x 1.2 inches
  • Shipping Weight: 1.8 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #1,893,436 in Books (See Top 100 in Books)

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3 of 7 people found the following review helpful:
4.0 out of 5 stars Refer to:, March 3, 2001
By A Customer
This review is from: Strategies for Organic Drug Synthesis and Design (Hardcover)
For impartial reviews of this book check:

- C.J. Spagnuolo, Journal of Medicinal Chemistry, 1999, 42:1113

- G. O'Sullivan, Synthesis, 1999, 6:1084

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Inside This Book (learn more)
First Sentence:
It is highly likely that those not themselves involved in scientific research perceive the development of new knowledge within a given area of science as a linear process. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
potentiating groups, compound cyclizes, ethanolic hydrogen chloride, carbethoxy group, lower side chain, imino chloride, basic ether, aromatic displacement, diaxial opening, more open face, acylation product, oxazole ring, benzyl protecting group, imine formation, bond reorganization, corresponding aniline, methylmagnesium bromide, alkylation product, compound starts, phosphorus oxychloride, chloroacetyl chloride, quaternary center, ethyl chloroacetate, lithium aluminum hydride, methanesulfonyl chloride
Key Phrases - Capitalized Phrases (CAPs): (learn more)
German Offen, Patent Appl, Tetrahedron Lett, New York, African Patent, Drugs Future, United States, Helu Chim, Spanish Patent, Van Cutsem
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