Structural Proteomics: High-Throughput Methods (Methods in Molecular Biology) [Hardcover]

Bostjan Kobe (Editor), Mitchell Guss (Editor), Thomas Huber (Editor)

Book Description

ISBN-10: 1588298094 | ISBN-13: 978-1588298096 | Publication Date: March 3, 2008 | Edition: 1

The objective of this volume is to provide readers with a current view of all aspects of the 'pipeline' that takes protein targets to structures and how these have been optimised. This volume includes chapters describing, in-depth, the individual steps in the Structural Genomics pipeline, as well as less detailed overviews of individual Structural Genomics initiatives. It is the first book of protocols to cover techniques in a new and emerging field.

Editorial Reviews

Review

From the reviews:

"This book compiles an impressive array of contributions from a variety of contributors … usually in a format that is accessible to any jobbing structural biologist, or those other molecular biologists with an linking to press their molecular targets into crystal screens or NMR tubes. … In sum, this is a book it is useful to have to hand … ." (Paul C. Driscoll, ChemBioChem, Issue 9, August, 2008)

"This book ... details some of the `tricks of the trade' involved in the field of structural genomics. ... This will be a useful text for laboratories already involved in fields covered in the book who want to increase the number of projects in the lab or for those who want to expand into neighbouring fields." (Darren Thompson, Microbiology Today, November, 2008)

From the Back Cover

Structural genomics is a newly emerging field that has arisen following the successful footsteps of the major sequencing efforts generally bundled under the heading "genomics". In Structural Proteomics: High Throughput Methods, readers are provided with a current view of all aspects of the 'pipeline' that takes protein targets to structures and how these have been optimized. This volume includes chapters describing in-depth the individual steps in the Structural Genomics pipeline, as well as overviews of individual Structural Genomics initiatives. Topics include Target Selection for structural genomics, Protein structure modeling, High-throughput cloning, Mass Spectrometry modeling. Structural Proteomics: High Throughput Methods, encourages its readers to access further details on the methodologies in on-line resources as well as in cited literature making it an invaluable resource. Most methods in this important book are as amenable to small laboratories as to large consortia, and do not require major investments in facilities. This essential volume provides insight into the diversity of approaches adopted by different laboratories and proves that 'high throughput' is really the defining characteristic of structural genomics.

Product Details

• Hardcover: 628 pages
• Publisher: Humana Press; 1 edition (March 3, 2008)
• Language: English
• ISBN-10: 1588298094
• ISBN-13: 978-1588298096
• Product Dimensions: 10.3 x 7.1 x 1.3 inches
• Shipping Weight: 3.6 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #2,632,964 in Books (See Top 100 in Books)