To understand the structure and dynamics of DNA and its interactions with ligands, a complete analysis of its confirmational flexibility is required. This volume and its companion, Volume 211 of Methods of Enzymology, collate in one source all the methods and approaches needed to achieve this goal.
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Editorial Reviews
Review
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
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Inside This Book
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First Sentence:
Visualizing DNA as a simple linear double helix is a serious oversimplification of its probable functional shape. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
binding density function, exolll stop, topoisomer spots, psoralen photobinding, titrant stock, average binding density, ligand binding density, osmium binding sites, osmium tetroxide complexes, repressor binding sequence, melt map, supercoiled minicircles, inner filter corrections, chemical cleavage approach, equilibrium binding isotherm, helix defects, polymerase approach, lac repressor complex, tract bend, ligase concentration, cyclization kinetics, density function analysis, equilibrium binding parameters, hairpin arms, radical cleavage pattern Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, New York, Academic Press, Cold Spring Harbor, Monte Carlo, Laboratory Manual, Boca Raton, Molecular Cloning, Adenine Press, National Institutes of Health, Promega Corp, New England Biolabs, Bethesda Research Laboratories, Nucleic Acid Res, Ultraviolet Products, College Station, San Gabriel, Trends Biochem New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Visualizing DNA as a simple linear double helix is a serious oversimplification of its probable functional shape. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
binding density function, exolll stop, topoisomer spots, psoralen photobinding, titrant stock, average binding density, ligand binding density, osmium binding sites, osmium tetroxide complexes, repressor binding sequence, melt map, supercoiled minicircles, inner filter corrections, chemical cleavage approach, equilibrium binding isotherm, helix defects, polymerase approach, lac repressor complex, tract bend, ligase concentration, cyclization kinetics, density function analysis, equilibrium binding parameters, hairpin arms, radical cleavage pattern Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, New York, Academic Press, Cold Spring Harbor, Monte Carlo, Laboratory Manual, Boca Raton, Molecular Cloning, Adenine Press, National Institutes of Health, Promega Corp, New England Biolabs, Bethesda Research Laboratories, Nucleic Acid Res, Ultraviolet Products, College Station, San Gabriel, Trends Biochem New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 23
books:
See all 23 books this book cites
- Molecular Cloning: A Laboratory Manual, Third Edition (3 volume set) by Joe Sambrook on 8 pages
- Detoxication and Drug Metabolism: Conjugation and Related Systems, Volume 77: Volume 77: Detoxification and Drug Metabolism (Methods in Enzymology) by Nathan P. Kaplan in Front Matter (1), and Front Matter (2)
- Biological Regulation and Development (Vol 3b) by Robert F. Goldberger on page 400
- Guide to Yeast Genetics and Molecular Biology, Volume 194: Volume 194: Guide to Yeast Genetics and Molecular Biology (Methods in Enzymology) by John N. Abelson in Front Matter
- Cell Biology by Seong S. Han in Front Matter
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