To understand the structures and dynamics of DNA and its interactions with ligands, a complete analysis of its confirmational flexibility is required. This volume and its companion, Volume 212 of Methods in Enzymology, collate in one source all the methods and approaches needed to achieve this goal.
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Editorial Reviews
Review
Praise for the Series
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
"The Methods in Enzymology series represents the gold-standard."
--NEUROSCIENCE
"Incomparably useful."
--ANALYTICAL BIOCHEMISTRY
"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page."
--BIO/TECHNOLOGY
"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection."
--CHEMISTRY IN INDUSTRY
"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced."
--AMERICAN SOCIETY OF MICROBIOLOGY NEWS
"If we had some way to find the work most often consulted in the laboratory, it could well be the multi-volume series Methods in Enzymology...a great work."
--ENZYMOLOGIA
"A series that has established itself as a definitive reference for biochemists."
--JOURNAL OF CHROMATOGRAPHY
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Inside This Book
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First Sentence:
Over the past several years, improvements in nucleic acid chemistry have led to many applications for oligonucleotides in biology and biochemistry. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
nonlocal optimization, symmetry check plots, umol synthesis, writhing value, multifrequency calorimetry, rotary shadow casting, approximate internal energy, isothermal mixing calorimetry, umol scale, local helix parameters, surface spreading methods, unique base pairs, cruciform extrusion, derivatized oligomer, protonated structure, contiguous guanines, amino resonances, imino resonances, magnetically induced birefringence, twist profile, exchanging strands, percent labeling, tray spreading, ester conformation, isomorphous structures Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, New York, Academic Press, Monte Carlo, Tetrahedron Lett, Adenine Press, Huynh Dinh, Practical Approach, Brookhaven Protein Data Bank, Cambridge Structure Data Base, Boca Raton, National Institutes of Health, Nucleosides Nucleotides, Principles of Nucleic Acid Structure, Applied Biosystems, Acta Crystallogr, Cold Spring Harbor Symp, Cell Biol, Digital Instruments, New Jersey, Tran Dinh, Brownlee Aquapore, Cambridge No Cam, Cold Spring Harbor Laboratory, Electron Microsc New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Over the past several years, improvements in nucleic acid chemistry have led to many applications for oligonucleotides in biology and biochemistry. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
nonlocal optimization, symmetry check plots, umol synthesis, writhing value, multifrequency calorimetry, rotary shadow casting, approximate internal energy, isothermal mixing calorimetry, umol scale, local helix parameters, surface spreading methods, unique base pairs, cruciform extrusion, derivatized oligomer, protonated structure, contiguous guanines, amino resonances, imino resonances, magnetically induced birefringence, twist profile, exchanging strands, percent labeling, tray spreading, ester conformation, isomorphous structures Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, New York, Academic Press, Monte Carlo, Tetrahedron Lett, Adenine Press, Huynh Dinh, Practical Approach, Brookhaven Protein Data Bank, Cambridge Structure Data Base, Boca Raton, National Institutes of Health, Nucleosides Nucleotides, Principles of Nucleic Acid Structure, Applied Biosystems, Acta Crystallogr, Cold Spring Harbor Symp, Cell Biol, Digital Instruments, New Jersey, Tran Dinh, Brownlee Aquapore, Cambridge No Cam, Cold Spring Harbor Laboratory, Electron Microsc New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 54
books:
See all 54 books this book cites
- Principles of Nucleic Acid Structure (Springer Advanced Texts in Chemistry) by Martin Egli on 7 pages
- Oligonucleotide Synthesis: A Practical Approach by M. J. Gait on 5 pages
- Dynamic Light Scattering: Applications of Photon Correlation Spectroscopy by R. Pecora on page 432, page 434, and page 435
- University of Oregon by Jesse Thomas in Front Matter, and page 263
- Detoxication and Drug Metabolism: Conjugation and Related Systems, Volume 77: Volume 77: Detoxification and Drug Metabolism (Methods in Enzymology) by Nathan P. Kaplan in Front Matter (1), and Front Matter (2)
See all 54 books this book cites
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