A Systems Theoretic Approach to Systems and Synthetic Bio... and over one million other books are available for Amazon Kindle. Learn more
Buy New
$189.00
Qty:1
Only 1 left in stock (more on the way).
Ships from and sold by Amazon.com.
Gift-wrap available.
A Systems Theoretic Appro... has been added to your Cart
Have one to sell? Sell on Amazon
Flip to back Flip to front
Listen Playing... Paused   You're listening to a sample of the Audible audio edition.
Learn more
See this image

A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems Hardcover – July 17, 2014

ISBN-13: 978-9401790468 ISBN-10: 9401790469 Edition: 2014th

Buy New
Price: $189.00
13 New from $137.53 4 Used from $122.04
Amazon Price New from Used from
Kindle
"Please retry"
Hardcover
"Please retry"
$189.00
$137.53 $122.04
Free Two-Day Shipping for College Students with Amazon Student Free%20Two-Day%20Shipping%20for%20College%20Students%20with%20Amazon%20Student


Best Books of the Year
See the Best Books of 2014
Looking for something great to read? Browse our editors' picks for 2014's Best Books of the Year in fiction, nonfiction, mysteries, children's books, and much more.
$189.00 FREE Shipping. Only 1 left in stock (more on the way). Ships from and sold by Amazon.com. Gift-wrap available.
NO_CONTENT_IN_FEATURE

Shop the New Digital Design Bookstore
Check out the Digital Design Bookstore, a new hub for photographers, art directors, illustrators, web developers, and other creative individuals to find highly rated and highly relevant career resources. Shop books on web development and graphic design, or check out blog posts by authors and thought-leaders in the design industry. Shop now

Product Details


Editorial Reviews

From the Back Cover

The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy.

Systems and control theory is a branch of engineering and applied sciences that rigorously deals with the complexities and uncertainties of interconnected systems with the objective of characterising fundamental systemic properties such as stability, robustness, communication capacity, and other performance metrics. Systems and control theory also strives to offer concepts and methods that facilitate the design of systems with rigorous guarantees on these properties. Over the last 100 years, it has made stellar theoretical and technological contributions in diverse fields such as aerospace, telecommunication, storage, automotive, power systems, and others. Can it have, or evolve to have, a similar impact in biology? The chapters in this book demonstrate that, indeed, systems and control theoretic concepts and techniques can have a significant impact in systems and synthetic biology.

Volume II contains chapters contributed by leading researchers in the field of systems and synthetic biology that concern modeling physiological processes and bottom-up constructions of scalable biological systems. The modeling problems include characterisation and synthesis of memory, understanding how homoeostasis is maintained in the face of shocks and relatively gradual perturbations, understanding the functioning and robustness of biological clocks such as those at the core of circadian rhythms, and understanding how the cell cycles can be regulated, among others. Some of the bottom-up construction problems investigated in Volume II are as follows: How should biomacromolecules, platforms, and scalable architectures be chosen and synthesised in order to build programmable de novo biological systems? What are the types of constrained optimisation problems encountered in this process and how can these be solved efficiently?

As the eminent computer scientist Donald Knuth put it, "biology easily has 500 years of exciting problems to work on". This edited book presents but a small fraction of those for the benefit of (1) systems and control theorists interested in molecular and cellular biology and (2) biologists interested in rigorous modelling, analysis and control of biological systems.

Customer Reviews

There are no customer reviews yet.
5 star
4 star
3 star
2 star
1 star
Share your thoughts with other customers

Set up an Amazon Giveaway

Amazon Giveaway allows you to run promotional giveaways in order to create buzz, reward your audience, and attract new followers and customers. Learn more
A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems
This item: A Systems Theoretic Approach to Systems and Synthetic Biology II: Analysis and Design of Cellular Systems
Price: $189.00
Ships from and sold by Amazon.com