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The Tangled Field : Barbara McClintock's Search for the Patterns of Genetic Control
 
 
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The Tangled Field : Barbara McClintock's Search for the Patterns of Genetic Control [Hardcover]

Nathaniel C. Comfort (Author)
4.0 out of 5 stars  See all reviews (1 customer review)


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Book Description

0674004566 978-0674004566 June 30, 2001 1

This biographical study illuminates one of the most important yet misunderstood figures in the history of science. Barbara McClintock (1902-1992), a geneticist who integrated classical genetics with microscopic observations of the behavior of chromosomes, was regarded as a genius and as an unorthodox, nearly incomprehensible thinker. In 1946, she discovered mobile genetic elements, which she called "controlling elements." Thirty-seven years later, she won a Nobel Prize for this work, becoming the third woman to receive an unshared Nobel in science. Since then, McClintock has become an emblem of feminine scientific thinking and the tragedy of narrow-mindedness and bias in science.

Using McClintock's research notes, newly available correspondence, and dozens of interviews with McClintock and others, Comfort argues that McClintock's work was neither ignored in the 1950s nor wholly accepted two decades later. Nor was McClintock marginalized by scientists; throughout the decades of her alleged rejection, she remained a distinguished figure in her field. Comfort replaces the "McClintock myth" with a new story, rich with implications for our understanding of women in science and scientific creativity.

(20010601)


Editorial Reviews

From Library Journal

Barbara McClintock received the Nobel prize in 1983 at age 81 for her work in corn genetics. Evelyn Fox Keller's biography of McClintock, A Feeling for the Organism, was published that same year. This current study by the deputy director of the Center for History of Recent Science, George Washington University, argues that Keller's description of McClintock's milieu and, indeed, McClintock's own description of her role in scientific society were often at odds with reality. Comfort suggests that rather than being a loner and maverick who served as a target of bias and narrow-mindedness, McClintock was always well respected and remained a distinguished figure in the scientific community until her death in 1992. The author develops several themes to explain McClintock's life, among them her need for independence and control over her own work. He also goes to great pains to explain the significance of her work at each stage. What he does not demonstrate is whether there really was substantial understanding of her work at the time that it was done. Certainly, after major development in related fields such as molecular biology, her early ideas were more appreciated. Regardless, this is an interesting work that provides insight into McClintock's work and personality. For academic libraries. Hilary D. Burton, Lawrence Livermore National Lab., CA
Copyright 2001 Reed Business Information, Inc.

From Booklist

McClintock was awarded the Nobel Prize in physiology and medicine in 1983 when she was 81 for her groundbreaking work in maize genetics performed decades earlier, and since then, she's been shrouded in myth. Comfort, the first biographer to have access to McClintock's papers, seeks to clarify her complex achievements in unveiling chromosomal behavior, which are not well understood, partly because of her famously quirky rhetorical style, her penchant for working alone, and the sad truth that, ultimately, she failed to fully realize the implications of her dazzling discoveries. Lucid, engaging, and unafraid of controversy, Comfort also dismantles the popular image of McClintock as a mystic and a female pioneer marginalized by male scientists. He portrays instead a highly respected and dedicated professional adamant about maintaining her personal and intellectual freedom, who possessed an astonishing attunement to complexity and pattern and a protean ability to rapidly solve intricate, multidimensional problems. McClintock may have been waylaid in the tangles of her brilliant, paradigm-challenging theories, but she was a unique, jaunty, and hardworking genius whose visionary experiments were essential to the evolution of genetics. Donna Seaman
Copyright © American Library Association. All rights reserved

Product Details

  • Hardcover: 368 pages
  • Publisher: Harvard University Press; 1 edition (June 30, 2001)
  • Language: English
  • ISBN-10: 0674004566
  • ISBN-13: 978-0674004566
  • Product Dimensions: 9.6 x 6.5 x 1.3 inches
  • Shipping Weight: 1.6 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
  • Amazon Best Sellers Rank: #2,493,907 in Books (See Top 100 in Books)

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7 of 8 people found the following review helpful:
4.0 out of 5 stars Great book, incredible geneticist, May 27, 2002
This review is from: The Tangled Field : Barbara McClintock's Search for the Patterns of Genetic Control (Hardcover)
After just barely discussing Dr. McClintock's work in my genetics class, I just had to know more. This book is very insightful, and it discusses her work thoroughly. Her use of corn plants in the discovery of jumping genes (transposable elements). Truly an interesting topic and an incredible geneticist who's discovery has no doubt changed all of genetic research. This book gets a bit more in to detail than people may want for just background information. It includes some diagrams of her work, etc. A great book in all that I will add to my library.
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Inside This Book (learn more)
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First Sentence:
Here is the Barbara McClintock most people think they know. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
subgene hypothesis, mutable genes, twin sectors, maize geneticists, maize controlling elements, bacterial geneticists, maize chromosomes, quantitative genes, variegation patterns, mutable loci, unstable genes, maize genetics, microbial geneticists, private myth, other geneticists, genic action, classical geneticists, gene action, classical cytogenetics, galactose operon, broken chromosome, phage group, genetics community, experimental evolution, controlling units
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cold Spring Harbor, Nobel Prize, Marcus Rhoades, Carnegie Institution, George Beadle, Harriet Creighton, New York, Joshua Lederberg, Long Island, Richard Goldschmidt, American Philosophical Society Library, Department of Genetics, Evelyn Fox Keller, Evelyn Witkin, National Academy of Sciences, Norton Zinder, Rollins Emerson, Ruth Sager, Thomas Hunt Morgan, United States, Lewis Stadler, Milislav Demerec, National Research Council, Oliver Nelson, Almiro Blumenschein
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