From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body’s non-neoplastic cells. Modern targeted therapies interact with defined molecules present on cancer cells, adding increased selectivity to their toxic effects. This book presents an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Targeted Therapies in Cancer
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Inside This Book
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ovarian epithelial cells, imatinib therapy, inhibitor bortezomib, mitoxantrone resistance, cancer stem cells, cellular drug resistance, ibritumomab tiuxetan, gene signatures, ovarian carcinoma cell lines, immune monitoring, anaplastic large cell lymphoma, lymphoma therapy, mantle cell lymphoma, patients with relapsed, ovarian carcinoma cells, colorectal cancer patients, metastatic colorectal cancer, tumour samples, protein microarrays, doxorubicin resistance, imatinib mesylate, metastasis formation, proteasome inhibition, lymphoma study group, therapeutic vaccination Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Clin Oncol, Proc Natl Acad Sci, Biol Chem, Springer-Verlag Berlin Heidelberg, Hans Neubauer, Eckhard Thiel, Natl Cancer Inst, Proteomic Expression Profiling of Breast Cancer, Nat Rev Cancer, Clin Invest, Exp Med, Ulrike Stein, Utz Krug, Nat Genet, New Molecular Therapy Targets, Reinhold Schäfer, Ann Oncol, Clin Pathol, Gynecol Oncol, Molecular Aspects of Metastasis, Surg Oncol, Balázs Györffy, Mol Cell Biol, Semin Oncol New!
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ovarian epithelial cells, imatinib therapy, inhibitor bortezomib, mitoxantrone resistance, cancer stem cells, cellular drug resistance, ibritumomab tiuxetan, gene signatures, ovarian carcinoma cell lines, immune monitoring, anaplastic large cell lymphoma, lymphoma therapy, mantle cell lymphoma, patients with relapsed, ovarian carcinoma cells, colorectal cancer patients, metastatic colorectal cancer, tumour samples, protein microarrays, doxorubicin resistance, imatinib mesylate, metastasis formation, proteasome inhibition, lymphoma study group, therapeutic vaccination Key Phrases - Capitalized Phrases (CAPs): (learn more)
Cancer Res, Clin Oncol, Proc Natl Acad Sci, Biol Chem, Springer-Verlag Berlin Heidelberg, Hans Neubauer, Eckhard Thiel, Natl Cancer Inst, Proteomic Expression Profiling of Breast Cancer, Nat Rev Cancer, Clin Invest, Exp Med, Ulrike Stein, Utz Krug, Nat Genet, New Molecular Therapy Targets, Reinhold Schäfer, Ann Oncol, Clin Pathol, Gynecol Oncol, Molecular Aspects of Metastasis, Surg Oncol, Balázs Györffy, Mol Cell Biol, Semin Oncol New!
Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Surprise Me!
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