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Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine
 
 
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Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine [Hardcover]

Ilse Zolle (Editor)

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Book Description

3540339892 978-3540339892 November 29, 2006 1
Radioactive drug development is a multi-disciplinary task. Therefore, dedicated scientists and experts from different fields of specialisation have contributed to this book. The text reviews forty years of advances in radiopharmaceutical development based on Technetium. The first section reviews basic principles and analytic methods, and information on chemical makeup of radiopharmaceuticals. Part 2 reviews 99mTc-radiopharmaceuticals used in nuclear medicine, thoroughly outlining their chemistry, formulation, pharmacokinetics and clinical applications.

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Editorial Reviews

Review

From the reviews: "This nicely organized and clearly illustrated book provides an up-to-date resource for radiopharmacists and nuclear medicine physicians who compound and prescribe 99mTc-labeled radiopharmaceuticals. Radiochemists and those concerned with regulatory affairs also will be interested, and the book could be used as a primary text in nuclear medicine training programs. This outstanding book fills a void and is the first compilation of its kind in many years. We recommend it with the highest enthusiasm." (Susan Z. Lever and John R. Lever, Journal of Nuclear Medicine, May, 2009)

From the Back Cover

This textbook gives an account of the accomplishments related to the development of 99mTc-radiopharmaceuticals and their application in diagnostic nuclear medicine. Since radioactive drug development is a multi-disciplinary task, experts working in nuclear medicine and research institutions have contributed valuable information concerning the preparation with sterile kits, methods of quality control, and the use of 99mTc-radiopharmaceuticals in patients. In addition, the legal aspects governing production and clinical application are also considered. Section 1 contains basic principles and methods used for analysis. Special emphasis is given to the analytical methods verifying pharmaceutical quality. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affection in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients. This book can serve for daily practice in nuclear medicine, serving as a reference source as well as a teaching tool.

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