Thermoregulation is vital for survival but the interplay between toxic insults and thermoregulatory mechanisms is often poorly understood. Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach is the first major text to study the integrative thermoregulatory responses of mammals that are exposed to toxicants. Because environmental physiology is also crucial in toxicological responses, this volume also examines the role of environmental temperature in the modulation of cellular mechanisms of toxicity. The book begins by explaining the importance of temperature in toxicological studies, and how all biological processes are dependent on temperature. It then reviews the basics of temperature regulation in homeotherms and poikilotherms, and addresses whole-animal and in vitro studies related to the effects of temperature on toxicity. The text examines thermoregulatory response to toxic insult, and how responses affect recovery and potential survival. It describes hypothermic response in rodents to febrile and hyperthermic reactions in humans, and discusses the relevance of heat and cold stress on human exposures to airborne pollutants and other toxicants. This volume provides an extensive comparison of physiological responses of invertebrates, fish, amphibians, and mammals, and focuses on the impact of endocrine disruption. It then considers how toxicants and thermal stress cause the expression of stress proteins, followed by a study of the impact of genetic variability. The book concludes with an examination of thermoregulatory response to natural toxins and venoms.
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Inside This Book
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First Sentence:
Biomedical researchers are often called upon to define when an insult triggers a so-called significant physiological disturbance. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
hypothermic efficacy, tachymetabolic species, hypothermic response, daytime core temperature, fever pathway, colonic probes, selected ambient temperature, thermoeffector response, metabolic thermogenesis, behavioral thermoregulatory response, hyperthermic response, tail skin temperature, oxidative uncouplers, regulated hypothermia, delayed hyperthermia, febrile effects, thermoregulatory effects, hypothermic effects, moregulatory responses, thermoregulatory studies, warm acclimation, hyperthermic death, parathion absorption, rebound hyperthermia, tail blood flow Key Phrases - Capitalized Phrases (CAPs): (learn more)
Gulf War, Regulated Gordon, Effects of Acute Exposure, Board Can, Rat Ethanol, Cambridge University Press, Thermal Biol New!
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Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Biomedical researchers are often called upon to define when an insult triggers a so-called significant physiological disturbance. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
hypothermic efficacy, tachymetabolic species, hypothermic response, daytime core temperature, fever pathway, colonic probes, selected ambient temperature, thermoeffector response, metabolic thermogenesis, behavioral thermoregulatory response, hyperthermic response, tail skin temperature, oxidative uncouplers, regulated hypothermia, delayed hyperthermia, febrile effects, thermoregulatory effects, hypothermic effects, moregulatory responses, thermoregulatory studies, warm acclimation, hyperthermic death, parathion absorption, rebound hyperthermia, tail blood flow Key Phrases - Capitalized Phrases (CAPs): (learn more)
Gulf War, Regulated Gordon, Effects of Acute Exposure, Board Can, Rat Ethanol, Cambridge University Press, Thermal Biol New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Table of Contents | First Pages | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 23
books:
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- Animal Physiology: Adaptation and Environment by Schmidt-Nielsen on page 2, page 157, and Back Matter
- Temperature Regulation in Laboratory Rodents by Christopher J. Gordon in Front Matter, page 28, and Back Matter
- Animal Physiology: Adaptation and Environment by Knut Schmidt-Nielsen on page 2, page 157, and Back Matter
- Thermoregulation: Physiology and Biochemistry by E. Schonbaum in Back Matter (1), and Back Matter (2)
- Temperature and life on page 18, and Back Matter
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