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Textbook of Bone Metastases
 
 
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Textbook of Bone Metastases [Hardcover]

Claude Jasmin (Editor), Rodolfo Capanna (Editor), Lawrence Coia (Editor), Robert Coleman (Editor), Gerard Saillant (Editor)

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Book Description

March 28, 2005 0471877425 978-0471877424 1
The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life.

Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials

This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates.

The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.


Editorial Reviews

Review

"This excellent reference text is recommended to both academic medical and hospital libraries…" (E-STREAMS, June 2006)

"...this textbook is comprehensive and will be a useful reference for medical students, oncologists, orthopedists, and general practitioners alike." (New England Journal of Medicine, November 24, 2005)

From the Back Cover

The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life.

Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials

The justification for a textbook on the subject of bone metastases is the quite remarkable progress made recently in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates.

The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the pathophysiology of bone metastases and therapeutics.. This book provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.


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Inside This Book (learn more)
First Sentence:
Malignant tumours occur in all higher multicellular organisms and have done so throughout evolution. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
primary bone lymphoma, pamidronate group, first skeletal complication, cancer patients with bone metastases, bone metastasis formation, skeletal morbidity rate, clodronate group, advanced multiple myeloma patients, treatment with clodronate, zoledronic acid group, new painful sites, developing bone metastases, new bone metastases, radiotherapy requirements, bloc spondylectomy, lytic bone disease, osteoblastic disease, hypercalcaemic episodes, oral clodronate, receiving pamidronate, actual pathological fracture, tumour cell invasion, metastatic bone disease, adjuvant clodronate treatment, skeletal metastatic disease
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Clin Oncol, Cancer Res, Clin Orthop, Nucl Med, Bone Joint Surg, Bone Min Res, New York, Textbook of Bone Metastases, Radiat Oncol Biol Phys, Clin Invest, Radiother Oncol, Ann Oncol, Biochem Biophys Res Commun, Semin Oncol, Clin Endocrinol Metab, Surg Oncol, Biol Chem, Nature Med, Ann Intern Med, Orthop Res, American Society of Clinical Oncology, Oxford University Press, Clin Radiol, John Wiley, Cancer Treat Rev
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