All of these Marvel complete collections on DVD-ROM are insanely great values, but this one is even better than the others. Like all of them, you get the classic stories from the '60s, the decent stories from the '70s and '80s, and the horrible stories from the '90s.
But whereas the Fantastic Four and Uncanny X-Men have been fairly undistinguished in the '00s, Amazing Spider-Man has had a superb run by J. Michael Straczynski. Straczynski's run up to 2006 is collected in ten graphic novels, which are... well, you can look the price up here on Amazon, if you want a precise number. But suffice it to say that if you just wanted to read those modern comics, and didn't care about the Lee/Ditko era or anything else before the turn of the century, you'd STILL be saving piles of money.
As far as the quality and ease-of-use of the comics go, my expectations have been met and exceeded, and I'm picky. The scans are high-quality two-page spreads (including all ads and letters and Bullpen Bulletins, which are interesting in their own right -- I can't wait until I start reading Hostess Fruit Pie ads) and show about as much detail as actually exists in the source. Plus, these are regular ol' PDFs, so there's no need to install some weird proprietary application on your computer (and Adobe Reader in full-screen mode on a 1600x1200 display is absolutely perfect for reading a two-page spread).
I bought this along with the Avengers, X-Men, and Fantastic Four sets, and am reading them all in parallel month-by-month, starting at the beginning. This doesn't quite fulfill my childhood dream of having every Marvel comic ever published and reading them all in order (though it'll get even closer once they release their Captain America, Hulk, and Thor DVDs), but it's a heck of a lot closer than I ever thought I'd get, for a heck of a lot less than I ever thought I'd have to pay.
I can't recommend these sets -- and particularly this one -- enough to any fan of Marvel superhero comics.
One very mild caveat: Like a few of the earlier reviewers, the version I got only went through mid-2006, not through the end of the year as in the picture and description above. On the one hand, that's unfortunate, as Straczynski's comics are good and worth reading; on the other hand, mid-2006 is already up to the point where it's into the "Civil War" stuff, which is crossover central (the Road to Civil War print collection that was just released, for instance, includes a few issues of Fantastic Four and two issues of Amazing Spider-Man (which actually are included on the DVD), so if you want to read those FF issues, you'd pretty much have to buy the print collection anyway). I wouldn't fuss about the missing months too much.