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The Biology of Cancer, 2nd Edition
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29 of 31 people found the following review helpful
The biology of cancer-first edition by Prof. R. A. Weinberg was an immediate hit. A masterpiece for clarity, sublime scholarship and style. The second edition has all of the qualities appreciated by the readers including a very solid chapters update. All chapters have been rewritten and new data added covering the latest trend in scientific literature. A DVD is included containing images and movies.
The book is further enhanced by a process of revision and update that magically cover almost any aspect, including immunology, therapy and cell biology. Prof. Weinberg is famous for scientific articles with a clear and incisive prose and the book offers all the nuances of his style. In addition, topics are extremely well integrated. Students and scientists will be happy to see how chapters are offering superlative insights with a unique perspective of the field. I was waiting the second edition for several years. And I am surprised to see how a masterpiece morphed into another one. Images and printing are state of the art.
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9 of 9 people found the following review helpful
on November 9, 2006
As a first year graduate student in a cancer biology department, I have found this book to be invaluable. Weinberg's style of writing is very thorough yet easy to follow. The classical experiments and research have been covered in detail, yet it is up to date on all the current cancer findings as well. There are also "sidenotes" included throughout the chapters that give the reader relevent information on the topic at hand without cluttering the actual text. I would recommend this book to fellow graduate students and for undergraduate cancer classes.

The book I ordered also came with a poster of "Pathways in Human Cancers" poster with much more details than Weinberg's "Subway map" of human cancer pathways.
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7 of 7 people found the following review helpful
on December 6, 2013
Definitely the right textbook for a comprehensive introduction to cancer. Like a giant review article, but with more breathing room to go into historical experiments and explain how we have arrived at the current understanding of cancer. And, lots of excellent illustrations and micrographs. You are getting more than a typical textbook; it is more like a work of literature. "Sidebars" are used often for things to read if you have the time.

If you are not an expert in cell biology, the book takes care to explain concepts in the context of cancer; for example, it gives a primer on the immune system at the beginning of the immunology chapter.

Note, this is not a textbook of cancers or pathology, but of our current understanding of how all cancers work, mostly at the molecular level. I am reading this as a medical student and for that purpose, it is both too long and missing the pathology that I need, but I don't regret it. Like I said, this textbook is more about providing a complete and up-to-date understanding for the science-minded individual. On that basis I can recommend it to an enthusiastic undergraduate.
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6 of 6 people found the following review helpful
on January 2, 2008
This book is a good book for anyone who is new to the cancer field; provided you have taken cell biology, maybe with a year of biochemistry. Having taken those classes myself, this book was still a bit much concerning the amount of information in it. This book can become complex at times, but cancer is no easy subject. This book comes with a CD with videos, mp3 lectures, power point slides, and a poster outlining some of the pathways of cancer formation. I really enjoyed the amount of supporting evidence and references that author gave for anyone interested in a particular sub topic within the chapters. Also the "cartoon" drawings that are common in biochem or biology books (protein structure, etc) are accompanied with a lot of "experimental" pictures such as those from an electron micrograph. I recommend this book for anyone in the biology, biochem, or chem fields that are interested in the cancer field. Oh and I'm not taking a class with this book (I wish said class was offered), I purchased it on my own to see if this is something I'd want to do in graduate school.
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6 of 6 people found the following review helpful
on July 1, 2013
This is a classic book but needed refreshing. The new edition is in many ways a completely new book with many new topics and excellent graphics. The writing style is fairly consistent throughout this very comprehensive look into the molecular biology of cancer. Useful to many different levels of readers, starting at the advanced high school level.
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5 of 5 people found the following review helpful
on April 14, 2014
I have read the book twice during my Ph D, the first time in the initial stage (version 1) and the second time when finishing (version 2). I bought a book of my own because I am reading it for the third time and I want to make marks on the book directly. Undoubtedly this is the best book for cancer biology!

1. It's suitable for all levels of readers, from fresh graduate students, senior graduate students, postdocs to even PIs.
2. It's very comprehensive, including basics and cutting-edge advances.
3. It's written in plain languages. Clearly, the author has spent efforts to consider how well the readers will absorb, rather than being arrogant and lecturing.
4. there is internal cohesion between the chapters. This is a typical advantage when the book is written by only one author. In the end, when finishing reading all, you will find everything makes so much sense when they are put together.
5. I particularly like the last chapter, a synopsis of rational design of therapeutics based on the mechanisms discussed in the previous chapters.
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6 of 7 people found the following review helpful
on November 27, 2013
Seriously, this was MORE FUN to read than I could have imagined. It is clearly a scholarly masterpiece but it is so well written and in the most interesting style that it is a tremendously enjoyable book to read. Dr. Weinberg takes the reader through the history of discoveries in oncology and in the most interesting way (exploring the initial discovery and how it was substantiated and why OR how it fell apart and why). Each chapter is a masterpiece of its own with detailed, clear, easy to follow figures and tables that enhance the text. Sidebar discussions scattered in the chapters deal with some of the most fascinating questions in biology/ oncology (conservation of gene function, how the powers of the immune system dictate whether transformed cells can form tumors, etc). Have not even gotten to the DVD yet but just finished reading this fascinating textbook. I am an internist with a Ph.D. in nutritional biochemistry and only, until recently, a passing interest in oncology. Really enjoyed reading this book and will reread it (have written in the margins, underlined). Recommend it highly, more than highly. The accompanying chart is one that I will be taking with me to an oncology conference in December and I bet it is extremely useful for putting presentations of research findings into context!
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4 of 4 people found the following review helpful
on September 26, 2013
It is impossible to keep up with the cancer literature. For example, over 40,000 papers have been published on p53 alone since 2003. In the first edition, Dr Weinberg distilled the vast cancer literature down into clear, concise, readable chapters with a focus on mechanisms rather than on say, lists of biomolecules. The figures were jewels! The second edition retains the stunning clarity of the first, but has much new information. The figures are even better.
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4 of 4 people found the following review helpful
on May 7, 2007
it is a must have book for someone in cancer research. It covers both molecular and biological aspects of cancer very well.
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2 of 2 people found the following review helpful
on July 29, 2014
My oncologist thinks Weinberg is the best. This is an amazingly well written book. I do not have a professional science background (although my husband does) but I was able to deal with it. It would help (a lot) to have biology at least at the level of a good intro college course. For the exciting material on cell signaling I found myself going to The Essential Cell Biology by Alberts et al. to pick up some background. When I took biology in college cell signaling was not the big deal it has become. Essential Cell Biology is another really great and well written book! On the other hand, the Biology of Cancer is not an oncology book. It is a basic science text. This is not to say that Weinberg does not mention clinical applications, but the focus is on understanding the basic science of cancer. Really, this is a great and fascinating read. I almost found myself cheering for the intrepid cancer cells no longer in my body (hopefully) Almost.
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