"This is a monumental book, which reviews and discusses over 3,000 scientific publications on mechanisms of aging and longevity, with special emphasis on the role of inflammation in senescence and age-related degenerative diseases. The author is an internationally recognized leader in the field of biogerontology, and his volume could serve as a useful reference book for a wide readership including biomedical scientists, biogerontologists and clinicians in areas of vascular disease, diabetes, obesity, Alzheimer disease and other neurodegenerative diseases, genetics of aging and longevity, animal models of aging, anthropology and primatology, evolutionary biology, demography and epidemiology." -Dr. Leonid Gavrilov and Natalia S. Gavrilova, Center on Aging, University of Chicago, in Quarterly Review of Biology (March 1, 2008)
"Finch exemplifies the ideal of thorough scholarship, and we should be grateful for his comprehensive summary of ideas and data that bear upon the intriguing question of why humans live as long as they do." -TOM KIRKWOOD, Institute for Ageing and Health, Newcastle University in Age and Ageing 2009; 38: 636–637
From the Back Cover
The book The Biology of Human Longevity - Inflammation, Nutrition, and Aging in the Evolution of Lifespans synthesizes several decades of top research, and expands a number of existing major theories, including the Barker theory of fetal origins of adult disease to consider the role of inflammation and Harmon's free radical theory of aging to include inflammatory damage. Future increases in lifespan are challenged by the obesity epidemic and spreading global infections which may reverse the gains made in lowering inflammatory exposure.
Professor Caleb Finch is one of the leading scientists of our time. Ranked in the top half of the 1 % most cited scientists, Professor Finch is director of the Gerontology Research Institute and the Alzheimer Research Center at the University of Southern California. He has received most of the major awards in biomedical gerontology. This book will be a scientific publishing event on the same level as his "Longevity, Senescence, and the Genome", published in 1990.
- A new synthesis expanding on existing ideas about the biology of longevity and aging
- Incorporates important research findings from several disciplines, including Gerontology, Genomics, Neuroscience, Immunology, Nutrition.
- A book of major importance from one of the great scientists of our time.