Start reading The Emperor of All Maladies: A Biography of Cancer on the free Kindle Reading App or on your Kindle in under a minute. Don't have a Kindle? Get your Kindle here.

Deliver to your Kindle or other device

Add Audible Narration
The Emperor of All Maladies: A Biography of Cancer Narrated by Stephen Hoye $34.99 $4.49
Enter a promotion code
or gift card
 
 
 

Try it free

Sample the beginning of this book for free

Deliver to your Kindle or other device

Sorry, this item is not available in
Image not available for
Color:
Image not available
 

The Emperor of All Maladies: A Biography of Cancer [Kindle Edition]

Siddhartha Mukherjee
4.7 out of 5 stars  See all reviews (1,155 customer reviews)

Print List Price: $18.00
Kindle Price: $11.99
You Save: $6.01 (33%)
Sold by: Simon and Schuster Digital Sales Inc
This price was set by the publisher

Free Kindle Reading App Anybody can read Kindle books—even without a Kindle device—with the FREE Kindle app for smartphones, tablets and computers.

To get the free app, enter your email address or mobile phone number.

Audible Narration

Switch back and forth between reading the Kindle book and listening to the Audible narration with Whispersync for Voice. Add narration for a reduced price of $4.49 when you buy the Kindle book.

Award-Winning Historians
Browse books by celebrated historians including Joseph J. Ellis, Lawrence Wright, and more. Learn more

Book Description

Winner of the Pulitzer Prize, and now a documentary from Ken Burns on PBS, The Emperor of All Maladies is a magnificent, profoundly humane “biography” of cancer—from its first documented appearances thousands of years ago through the epic battles in the twentieth century to cure, control, and conquer it to a radical new understanding of its essence.

Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with—and perished from—for more than five thousand years.

The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist.

From the Persian Queen Atossa, whose Greek slave may have cut off her diseased breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease.

Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.


Editorial Reviews

Amazon.com Review

Amazon Best Books of the Month, November 2010: "In 2010, about six hundred thousand Americans, and more than 7 million humans around the world, will die of cancer." With this sobering statistic, physician and researcher Siddhartha Mukherjee begins his comprehensive and eloquent "biography" of one of the most virulent diseases of our time. An exhaustive account of cancer's origins, The Emperor of All Maladies illustrates how modern treatments--multi-pronged chemotherapy, radiation, and surgery, as well as preventative care--came into existence thanks to a century's worth of research, trials, and small, essential breakthroughs around the globe. While The Emperor of All Maladies is rich with the science and history behind the fight against cancer, it is also a meditation on illness, medical ethics, and the complex, intertwining lives of doctors and patients. Mukherjee's profound compassion--for cancer patients, their families, as well as the oncologists who, all too often, can offer little hope--makes this book a very human history of an elusive and complicated disease. --Lynette Mong


From Publishers Weekly

Starred Review. Mukherjee's debut book is a sweeping epic of obsession, brilliant researchers, dramatic new treatments, euphoric success and tragic failure, and the relentless battle by scientists and patients alike against an equally relentless, wily, and elusive enemy. From the first chemotherapy developed from textile dyes to the possibilities emerging from our understanding of cancer cells, Mukherjee shapes a massive amount of history into a coherent story with a roller-coaster trajectory: the discovery of a new treatment--surgery, radiation, chemotherapy--followed by the notion that if a little is good, more must be better, ending in disfiguring radical mastectomy and multidrug chemo so toxic the treatment ended up being almost worse than the disease. The first part of the book is driven by the obsession of Sidney Farber and philanthropist Mary Lasker to find a unitary cure for all cancers. (Farber developed the first successful chemotherapy for childhood leukemia.) The last and most exciting part is driven by the race of brilliant, maverick scientists to understand how cells become cancerous. Each new discovery was small, but as Mukherjee, a Columbia professor of medicine, writes, "Incremental advances can add up to transformative changes." Mukherjee's formidable intelligence and compassion produce a stunning account of the effort to disrobe the "emperor of maladies." (Nov.) (c)
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

Product Details

  • File Size: 10196 KB
  • Print Length: 610 pages
  • Publisher: Scribner; Reprint edition (November 16, 2010)
  • Sold by: Simon and Schuster Digital Sales Inc
  • Language: English
  • ASIN: B003UYUP58
  • Text-to-Speech: Not enabled
  • X-Ray:
  • Word Wise: Enabled
  • Lending: Not Enabled
  • Amazon Best Sellers Rank: #4,610 Paid in Kindle Store (See Top 100 Paid in Kindle Store)
  •  Would you like to give feedback on images?


Customer Reviews

Most Helpful Customer Reviews
1,104 of 1,160 people found the following review helpful
5.0 out of 5 stars OFF THE CHARTS November 11, 2010
Format:Hardcover
You remember the scene in the film "Butch Cassidy and the Sundance Kid"? From the top of the bluff looking into the distance at dusk, Butch sees the lights of the pursuing posse which doesn't stop tracking them even at night and says "How many are following us? They're beginning to get on my nerves. Who are those guys?" In the same threatening way cancers have been dogging human beings since the dawn of time, and although we now know quite a lot about cancer we still don't really know "who are those guys" or how to shake them. And they sure are "beginning to get on our nerves" as Butch said. Almost one out of four of us will eventually wrestle with cancer -- the defining illness of our generation -- and lose our lives in the process. Until it catches up with us most of us will try to ignore this fact, just as when we were very young children alone in our bedroom trying to go to sleep at night we tried to ignore the monster that we sometimes feared might be lurking in our bedroom closet.

Enter oncologist Siddhartha Mukherjee who almost parentally takes us by the hand to give us the courage to open with him the door to that dark and foreboding closet in order to see what is really lurking inside. Since eventually most of us are going to have to wrestle with this monster anyway -- either as a victim or as a loved one of a victim -- looking intelligently and closely into that dark closet does diminish fear and enhance wise perspective. And on this incredible journey into the depths of that darkness, what an absolutely marvelous guide is this modern day Virgil called Siddharta Mukherjee as he leads us on this long and often harrowing journey through the swarth that cancer has cut through mankind throughout time.

Mukherjee is a veritable kaleidoscope.
Read more ›
Was this review helpful to you?
233 of 257 people found the following review helpful
5.0 out of 5 stars The Burden, The Mass, Onkos November 13, 2010
Format:Hardcover|Verified Purchase
**I am pleased that Dr. Mukherjee has won the Pulitzer prize in general non fiction for this book, 4-18-11

In the United States one in three women and one in two men will develop cancer in their lifetime. Dr Siddhartha Mukherjee, a medical oncologist, has written a definitive history of cancer. It may be one of the best medical books I have read. Complex but simple in terms of understanding. A timeline of a disease and those who waged the wars. In 1600 BC the first case of probable breast cancer was documented. In the thousands of years since, the Greek word, 'onkos', meaning mass or burden, has become the disease of our time. Cancer. The title of the book, is "a quote from a 19Th century physician" Dr Mukherjee had found inscribed in a library book that "cancer is the emperor of all maladies, the king of our terrors".

As a health care professional and as a woman who is six years post breast cancer, Cancer has played a big part in my life. I used to walk by the Oncology clinic, and quicken my pace. I used to give chemotherapy to my patients, before it was discovered that the chemo was so toxic that it needed to be made under sterile conditions and given by professionals who specialized in Oncology. Dr Mukherjee, wisely discusses cancer in the context of patients, those of us who suffer. After all it is because of the patients, the people who have gone before us, who have contracted some form of cancer, they are the base of this science.

Dr Mukherjee started his immersion in cancer medicine at the Dana Farber Cancer Institute in Boston. He relates the beginning of the study of ALL, Acute Lymphocytic Leukemia, by Dr Sidney Farber in 1947. Dr Farber, a pathologist at the time decided to change his focus and start caring for patients.
Read more ›
Was this review helpful to you?
194 of 219 people found the following review helpful
5.0 out of 5 stars The Everyman Book of Cancer November 12, 2010
By Prasant
Format:Hardcover|Verified Purchase
The brilliance of this book is the effortlessness with which the author draws the reader into the world of cancer and keeps him there as a tourist or witness. Dr. Mukherjee's engaging style, precision of prose and overwhelming compassion imbue this work with an energy that carries the reader along a ride like none other.

Whether the reader is a basic scientist or sociologist, a patient or healthcare provider, a philosopher or philanderer, this book will appeal, entertain and educate.

A remarkable achievement.
Comment | 
Was this review helpful to you?
70 of 77 people found the following review helpful
5.0 out of 5 stars "Cancer was an all-consuming presence in our lives." November 20, 2010
Format:Hardcover
Siddhartha Mukherjee's monumental "The Emperor of All Maladies" meticulously outlines the trajectory of cancer (derived from the Greek word "karkinos," meaning crab) over thousands of years, starting in ancient Egypt. In 2010, seven million people around the world will die of cancer. Many have experienced the horrors of this disease through personal experience. The author provides us with a global view of this "shape-shifting entity [that is] imbued with such metaphorical and political potency that it is often described as the definitive plague of our generation."

In "The Emperor of All Maladies," we meet a variety of patients, doctors, scientists, and activists. We also hear the voices of such iconic figures as Susan Sontag, author of "Illness as Metaphor," and Alexander Solzhenitsyn, whose "Cancer Ward" is a desolate and isolating "medical gulag." Cancer is such a complex subject that it can only be understood by examining it in all of its facets: through myths, the anguish of its victims, and the untiring efforts of its adversaries, both past and present, some of whom were well-meaning but horribly misguided. Mukherjee says in his author's note that he has made an effort to be "simple but not simplistic." In this he has succeeded.

Ancient physicians thought that such invisible forces as "miasmas" and "bad humors" caused cancers. Many years of experimentation, studies of human anatomy, laboratory work, and clinical trials have shown cancer to be a "pathology of excess" that originates from the uncontrolled growth of a single cell. Cancer is "unleashed by mutations--changes in DNA that specifically affect genes that incite unlimited cell growth." What treatment to use--surgery, radiation, chemotherapy, or a combination of these approaches--is rarely an easy decision.
Read more ›
Was this review helpful to you?
Most Recent Customer Reviews
4.0 out of 5 stars Four Stars
Informative-slow paced
Published 3 hours ago by Sidney Bennett
4.0 out of 5 stars In Depth
Very in depth coverage of the Big C. At times the politics of it all can be dry, especially the discussing of the donors and charities.
Published 22 hours ago by James Moore
5.0 out of 5 stars Insightful book
Great book. I recommend this to everyone looking to understand cancer. The book does not shy away from the gruesome facts of the disease. Read more
Published 1 day ago by caroline
5.0 out of 5 stars Five Stars
Great read!
Published 3 days ago by Chase
5.0 out of 5 stars Five Stars
Thoroughly enjoyed it. Highly recommend it.
Published 3 days ago by Ken Shore
5.0 out of 5 stars An Historical Biography of Understanding of the Complexity of Cancer
This is a worthy awardee of the Pulitzer Prize: An Amazing biography of cancer.
Published 5 days ago by Lee Skandalaris
5.0 out of 5 stars Excellent.
Fantastic. Very readable.
Published 7 days ago by Kevin Hauck
5.0 out of 5 stars Makes me happy to live now
This book reveals the dark mysteries of cancer and approaches to treatment and cure. Makes me happy to live now, instead of the deep dark past of the 50-60s, when people were... Read more
Published 8 days ago by C. Glass
4.0 out of 5 stars Four Stars
It is OK
Published 8 days ago by ramirz
5.0 out of 5 stars Packed with information and highly interesting
I previously worked at an oncology society and my boss there recommended this book. Two short years later, I've finally finished it. Read more
Published 9 days ago by Steve
Search Customer Reviews

More About the Author

Siddhartha Mukherjee is a cancer physician and researcher. He is an assistant professor of medicine at Columbia University and a staff cancer physician at the CU/NYU Presbytarian Hospital. A former Rhodes scholar, he graduated from Stanford University, University of Oxford (where he received a PhD studying cancer-causing viruses) and from Harvard Medical School. His laboratory focuses on discovering new cancer drugs using innovative biological methods. Mukherjee trained in cancer medicine at the Dana Farber Cancer Institute of Harvard Medical School and was on the staff at the Massachusetts General Hospital. He has published articles and commentary in such journals as Nature, New England Journal of Medicine, Neuron and the Journal of Clinical Investigation and in publications such as the New York Times and the New Republic. His work was nominated for Best American Science Writing, 2000 (edited by James Gleick). He lives in Boston and New York with his wife, Sarah Sze, an artist, and with his daughter, Leela.

Amazon Author Rankbeta 

(What's this?)

What Other Items Do Customers Buy After Viewing This Item?


Forums

There are no discussions about this product yet.
Be the first to discuss this product with the community.
Start a new discussion
Topic:
First post:
Prompts for sign-in
 


Look for Similar Items by Category