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The End of Illness Hardcover – January 17, 2012


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Product Details

  • Hardcover: 352 pages
  • Publisher: Free Press; 1 edition (January 17, 2012)
  • Language: English
  • ISBN-10: 1451610173
  • ISBN-13: 978-1451610178
  • Product Dimensions: 9.2 x 6.4 x 1.1 inches
  • Shipping Weight: 1.2 pounds (View shipping rates and policies)
  • Average Customer Review: 3.3 out of 5 stars  See all reviews (262 customer reviews)
  • Amazon Best Sellers Rank: #28,897 in Books (See Top 100 in Books)

Editorial Reviews

Review

“In this brilliant book, David Agus introduces a whole new way of looking at illness and health. Taking a cue from physics, he views the body as a complex system and helps us see how everything from cancer to nutrition fits into one whole picture. The result is both a useful guide on how to stay healthy and a fascinating analysis of the latest in medical science.”
--Walter Isaacson, author of Steve Jobs

“Dr. David Agus has given us a remarkable peek into our health--and the impact will be profound. I’ve made it my mission in life to live strong and help others do the same. The End of Illness is one more empowering piece to the puzzle of knowing how to do just that. This book will prevent illness, revolutionize treatments, and lengthen people's lives. A tour de force in its delivery and message.”
-- Lance Armstrong, 7-time Tour de France winner and Founder and Chairman, LIVESTRONG

“David Agus is one of America’s great doctors and medical researchers, a man dedicated to improving the health of as many people as he can. Written in a style and format that will truly engage readers, The End of Illness presents a dramatic, new way of thinking about our own health—a way that could lead to greatly improving the quality of life for millions, starting right now.”
-- Al Gore, 45th Vice President of the United States, Nobel Laureate in Peace, 2007

“As physician, research scientist, and friendly guide, Dr. Agus takes his readers on a fascinating tour of ideas and facts about health and illness. They will find many of those ideas to be unconventional and thought-provoking and many of the facts to be both striking and surprising. Read this book and you will very likely change at least some of your views on health and illness.”
-- Murray Gell-Mann, PhD, Nobel Laureate in Physics, 1969, and Distinguished Fellow and Cofounder of The Santa Fe Institute

“David Agus's The End of Illness is a brilliant blend of enlightening manifesto and practical how-to in the realm of our most important ingredient to a long and happy life: health. Filled with unorthodox ideas backed with hard science, it simplifies for the reader the complexity of vital developments happening in medicine today and teaches us how to make the most of what's available, as well as what's soon to come.”
– Michael Dell, Founder, Chairman, and Chief Executive Officer of Dell, Inc.

“Dr. David Agus is surfing the crest of two great waves of innovation -- in information technology and the life sciences. His End of Illness uses Big Data to decode the personal and molecular basis of disease. And, more important, advance a new model for health where prevention is key.
-- John Doerr, partner Kleiner Perkins Caufield Byers

"David Agus, one of the nation's most innovative cancer doctors, shatters the myths about health and wellness and provides us with a handbook for living a long, healthy life."
-- Steve Case, Chairman of Revolution and The Case Foundation, co-founder America Online

“In this seminal book, Dr. David Agus presents a brilliant new model of health based on the body as a complex system with an emphasis on prevention. The End of Illness may reframe everything you thought you knew about health. It is both provocative and inspiring. Highly recommended.”
-- Dean Ornish, MD founder and president of the Preventive Medicine Research Institute, Clinical Professor of Medicine at the University of California, San Francisco

“Dr. David Agus has been disrupting medicine as we know it for his entire career. Now, he brings his ideas out of the lab and exam room and into the lives of everyone—showing us how to live long, healthy, disease-free lives. Reading this book is the best thing you can do for yourself and your loved ones. A monumental work that will change your life.”
-- Marc Benioff, Chairman and CEO, salesforce.com

David Agus is one of the great medical thinkers of our age. "The End of Illness" reframes the entire discussion of sickness and health. Instead of thinking about disease Agus thinks about the system that is the human body, and what we need to do to guide it toward health. Before you take your next vitamin, read this book.
— Danny Hillis, PhD, Co-founder, Applied Minds and Thinking Machines

“What you will find in this book are clear and compelling reasons to be more pro-active about your health. The sections explaining physiology and the latest medical findings are very good, and are far more persuasive than the usual lectures we are given about all our bad habits. To misquote the Hippocratic Oath, ‘First do no harm.’ It will do you no harm to dream of the end of illness, but until that time, it might just do you some good to follow Agus’s eminently sensible advice.”
The Globe and Mail

About the Author

David B. Agus, MD, is a professor of medicine and engineering at the University of Southern California and heads USC’s Westside Cancer Center and the Center for Applied Molecular Medicine. He is a CBS News contributor.  He lives in Beverly Hills, California.

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More About the Author

Dr. David B. Agus is a professor of medicine and engineering at the University of Southern California Keck School of Medicine and Viterbi School of Engineering and heads USC's Westside Cancer Center and the Center for Applied Molecular Medicine. He is one of the world's leading cancer doctors, and the co-founder of two pioneering personalized medicine companies, Navigenics and Applied Proteomics. Dr. Agus is an international leader in new technologies and approaches for personalized healthcare and a contributor to CBS News. His first book, The End of Illness, became a New York Times #1 and international bestseller and was also the subject of a PBS special. Dr. Agus' new book "A Short Guide to a Long Life" was published by Simon & Schuster on January 7, 2014 and is now a New York Times bestseller.

Customer Reviews

Dr. Agus is not a Statistician.
scientist99
I think we can do better than some TV doctor talking up his book on a comedy show (Jon Stewart).
C. Martin
I read this book and feel it is very misleading.
Barron

Most Helpful Customer Reviews

754 of 771 people found the following review helpful By AppleTexts on February 8, 2012
Format: Hardcover
I got this book after seeing some of the five-star reviews, and watching the author's January 9 pre-publication interview with Connie Chung. I've now read it, and I found it provocative and engaging. The author describes the relevant studies in an easy, conversational manner, and he presents convincing cases for several different life-style changes:

(1) Taking a baby aspirin a day might well save your life.

(2) If you spend a lot of time sitting down on the job, get up every once in a while and walk around. Take the stairs when possible. That could add years to your life.

(3) Frozen fruit is probably better for you than "fresh" fruit. As a result, making smoothies is probably better than juicing.

(4) As the costs of whole genome sequencing come down (and patent issues are resolved), people would be well advised to get their genome read and diagnosed - whether by this author's company or another's. While genes don't tell the whole story, they can be very indicative of preventable problems. And prevention is far preferable to treatment.

(5) Do whatever you can to avoid the release of stress hormones - those can cut your life short too. Obviously stay clear of stressful situations (or develop coping mechanisms); less obviously, try to eat your meals on a regular schedule, and keep a regular sleep schedule.

(6) Do what you can to avoid inflammation generally - inflammation can have long-term effects. Taking a daily aspirin is a good start; getting a regular flu shot might be another.

A bit more controversial are his recommendations regarding statins and nutritional supplements.
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1,445 of 1,521 people found the following review helpful By LuvUrPets on January 22, 2012
Format: Kindle Edition Verified Purchase
For once, I fell for the hype surrounding a book but after reading "The End of Illness" I realized I should have stuck with my original plan to check it out from my library. There is absolutely nothing groundbreaking or particularly significant about anything contained in this book. So why give it three stars? It does contain basic, medically supported info that some older person who has had no tv, no internet, no newspaper, and no radio access for the last 30 years and refuses to go to the doctor or listen to his doctor would need to know. As for the rest of us, all this book does is confirm what you already knew or suspected.

I am assuming though that you're interested in this book because you want to: (a) avoid an illness, particularly a life threatening illness or (b) you already have an illness and think this book will give suggestions on how to improve your life and get control of your illness. Learning about new advances in medicine which may or may not lead to anything that will help you during your lifetime is just a bonus but not high on your list of priorities. To be truthful, even if you read the book for that last purpose, you'd still be disappointed. I'm one of those unlucky people who was diagnosed with a chronic illness at the tender age of 13. Before then, nothing major happened in my life to kick start the illness - no drug use, no past illnesses/accidents, no lack of exercise, no atrocious diet, no lack of sleep habits, not a genetic disease. Sometimes $%&@ happens. As a mid 30s person, I'm pretty well versed in health matters but not an expert by far. I suspect many people my age and slightly older already know about the "tools" Dr. Agus "details" in this book and probably have been using them for years.
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377 of 441 people found the following review helpful By William B. Grant on February 12, 2012
Format: Hardcover
This book may have some good points regarding lifestyle choices, but in my field of expertise, vitamin D, misses the mark by a wide margin. Vitamin D is a natural compound that humans have required forever. Thus, much of what we know about the roles of vitamin D come from ecological (geographical or seasonal) and observational studies. Randomized controlled trials (RCTs) have provided very good evidence that vitamin D reduces the risk of cancer, hip fractures, type A influenza, pneumonia, increase survival after diagnosis of cardiovascular disease, and reduce all-cause mortality rate. A recent RCT found that pregnant and nursing women need at least 4000 IU/d and that there are no adverse effects. The reasons why there are not more successful randomized controlled trials with vitamin D reported are several: most studies used only 400 IU/d vitamin D, the benefical effects of vitamin D for many types of disease have been identified in the past few years, there are many sources of vitamin D such as food, supplements and solar UVB, and there is considerable person-to-person variability in serum 25-hydroxyvitamin D with respect to oral vitamin D intake. The author dismisses the benefit of vitamin D for reducing the risk of cancer based in part on a 2008 International Agency for Research on Cancer (IARC) report. The authors of that report were primarily dermatologists who consider their mission in life to keep people out of the sun in order to prevent melanoma and skin cancer. This report has been shown to be highly biased. The author also suggests that cancer rates are higher at high latitudes due perhaps to genomic effects.Read more ›
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