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Samantha Willows (Leighton Meester) is a bright-eyed college freshman ready to endure the often humiliating traditions of pledge week if it means being accepted into Delta Phi Theta, one of the most prestigious sororities in the country. But her enthusiasm turns to dread when she begins to sense something sinister about the sorority house and some of its sisters, who appear to be sharing a closely guarded secret. After the death of a Delta Phi Theta member, Samantha considers the unimaginable could an evil, murderous force reside within the walls of the sorority house?