This groundbreaking analysis reveals how more than 100 years ago, the English scientist Dr. John Beard uncovered not only the likely origins of cancer but also its solution. Dr. Gonzalez explains Dr. Beard's underlying theory and explores Dr. Beard's pioneering use of pancreatic enzymes for cancer treatment. This book also showcases case histories describing cancer patients successfully treated with pancreatic enzymes by the authors.
Dr. Beard's achievements, though unappreciated in his own day, are many. A research embryologist by training, he proposed that the early mammalian placenta, or trophoblast, the connection between the embryo and the maternal uterine blood supply, represents an ideal model for the study of malignancy. In its ability to divide rapidly, invade maternal tissues, and generate a blood supply, the trophoblast, Beard reasoned, initially behaves as any growing tumor might. However, the trophoblast differs from malignancy, Beard stated, because at some predetermined point it changes from an invasive tissue into the non-aggressive placenta, necessary for early embryonic life.
Beard spent years searching for the key to this remarkable transformation, ultimately discovering that the very day the trophoblast changes character, the embryonic pancreas begins secreting large amounts of enzymes. Beard then proposed that since pancreatic enzymes regulate trophoblast growth, they must represent our main defense against cancer. Subsequently, in animal experiments and in clinical use with human cancer patients, Beard demonstrated pancreatic enzymes could attack and destroy cancerous tumors.
In this book, you will read of Dr. Beard's discoveries, and how modern science confirms much of what he long ago proposed. Along the way, you will learn that Dr. Beard discovered stem cells, the focus of much research effort today, though he never received proper credit. And you will see that Dr. Beard may have uncovered the key to the deadly disease of cancer.
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72 of 72 people found the following review helpful
By J. V. Wright
Format:Paperback
It's not extremely common, so unless you're a health care professional or student, you've likely never heard or read of "choriocarcinoma." This invasive and often metastasizing cancer usually originates in the beginnings of a placenta. A choriocarcinoma starts out as all placentas do, as a tissue called "trophoblast" rapidly invading the lining of the uterus. But instead of "switching off" it's invasiveness once it's established, and turning into a mature placenta to nourish the developing infant, a the ever-invading trophoblast--now called a choriocarcinoma--just keeps invading and invading. If it isn't stopped, it will metastasize just like any other cancer--and ultimately kill it's "host."
But if it isn't common, why am I bringing it up? Especially since many of you are done having babies and raising your families? Well, according to some very recent research, it appears that this very specific type of "women's cancer" may actually hold the key to curing many other cancers--in both men and women.
In their new book, The Trophoblast and the Origins of Cancer, Drs. Nicholas Gonzalez and Linda Isaacs reveal that many cancers in both men and women invade surrounding tissue in the exact same way that choriocarcinomas do, using the exact same bio-chemical pathways, signaling molecules, and enzymatic processes.
In 2007, one prominent research group wrote: "Trophoblast research over the past decades has underlined the striking similarities between the proliferative, migratory and invasive properties of placental cells and those of cancer cells. This review recapitulates the numerous key molecules, proto-oncogenes, growth factors, receptors, enzymes, hormones, peptides and tumour-associated antigens (TAAs) expressed by both trophoblastic and cancer cells."
And in an even earlier publication, another group of researchers wrote: "There are striking similarities present between the behavior of invasive placental cells and that of invasive cancer cells. In this review, we propose that cellular mechanisms used by the cells of the placenta during implantation are reused by cancer cells to invade and spread within the body."
So what can we do with this information? Cure cancer, that's what! In fact, it's been done before.
As Drs. Gonzalez and Isaacs report, a Scottish embryologist by the name of Dr. John Beard pioneered this cancer treatment in 1905--more than 100 years ago.
Using only microscopes and none of the "high-tech" instrumentation of the late 20th and early 21st centuries, Dr. Beard observed the uncanny similarities between the growth of the trophoblast (remember, that's the name for the still-developing placenta) and the growth and development of "regular" cancers. But Beard went much further than that.
He reasoned that since 99.99 percent (or more) of all human trophoblasts "switch off" their invasiveness, and morph into mature placentas, possibly the same "switch off"--whatever it might be--could be applied to "regular" cancers. Dr. Beard finally found that "off switch" in the pancreas of the developing baby.
In humans and every mammalian species he studied, the very same day the baby's pancreas first started to secrete digestive enzymes (particularly trypsinogen, trypsin, and chymotrypsin, but also amylase, lipase, elastase, and many others), the invasiveness of the trophoblast began to switch off and it rapidly changed into a mature placenta.
So Dr. Beard did the obvious thing: He injected pancreatic enzymes into animals with cancer--and found that it had a strong anti-cancer effect.
In 1911, he published a book about his observations, The Enzyme Treatment of Cancer. Having heard or read of Dr. Beard's work, many other physicians successfully treated patients with cancer using injectable pancreatic enzymes. In their new book, Drs. Gonzalez and Isaacs point to several reports about these successes published between 1906 and1908, including two published in the Journal of the American Medical Association (JAMA) and the British Medical Journal (BMJ).
So whatever happened to this carefully researched, successful and entirely natural cancer treatment pioneered more than a century ago? For once, it wasn't los Federales--at least, not in the beginning.
The FDA didn't get around to outlawing injectable pancreatic enzymes until 1966. As Drs. Gonzalez and Isaacs explain, there were at least two other major factors that explain why Dr. Beard's cancer treatment didn't catch on.
One was tremendous opposition from "organized medicine." As is so often the case in medicine and other so-called "learned professions," "what you're not up on, you're down on." So medical journals wrote editorials against him, and numerous professors gave lectures denouncing his findings and procedures.
The other even more significant factor was the extremely variable quality of available injectable pancreatic enzyme preparations. At the time, many of them were so poor that they were worthless in cancer therapy. So the lack of results from their use were cited as "proof" that pancreatic enzymes didn't work at all.
But the naysayers weren't loud enough to get everyone to stop using this therapy. One St. Louis doctor reported success treating advanced cancer patients with injectable pancreatic enzymes in the 1920s and 1930s. And in the 1950s, Dr. Frank Shively, a surgeon practicing in Dayton, Ohio, started giving a single pancreatic enzyme--trypsin--by intravenous injection to terminal, inoperable cancer patients. By 1966, he'd given 1,305 injections of pancreatic enzymes (by then he'd also included pepsinogen, desoxyribonuclease and ribonuclease) to 193 terminal cancer patients without adverse reactions.
But by the 1960s, the cancer chemotherapy industry had really taken off. And that's when los Federales stepped in. In 1966, the FDA ordered Dr. Shively--and everyone else using this treatment--to stop giving injectable pancreatic enzymes to cancer patients. So any possible competition to the cancer chemotherapy industry from injectable pancreatic enzymes was stopped before it could get started.
Fortunately, at about the same time, a Texas orthodontist--William Donald Kelley--decided to treat his own cancer with (among other things) large doses of pancreatic digestive enzymes taken orally. As Drs. Gonzalez and Isaacs explain, Dr. Kelley knew nothing of Dr. Beard, but took the enzymes because his own digestive function was so bad. The more enzymes he took, the more his cancer shrank. Combining the enzymes with individualized diet plans, multiple supplements, and detoxification procedures including coffee enemas, Dr. Kelley cured not only his own cancer, but eventually helped cure many others as well.
In the early 1980s, Dr. Gonzalez studied thousands of Dr. Kelley's records and interviewed hundreds of his patients, and found that these treatments worked in a significant number of cases.
After learning thoroughly about Dr. Kelley's approach and the success his patients had experienced, Dr. Gonzalez opened his own cancer-treatment practice in New York City using many of the same principles. Suzanne Somers' 2009 book Knockout: Interviews with Doctors Who Are Curing Cancer and How to Prevent Getting it in the First Place features an extensive interview with Dr. Gonzalez as well as interviews with several of the cancer survivors he's successfully treated.
Let's finish by summarizing Trophoblast. All of its discussion and meticulous documentation is very important-- particularly for medical professionals--but it really all boils down to this: Very many cancers invade surrounding tissues and grow and metastasize using exactly the same mechanisms used by the precursor of the placenta (the trophoblast). And just as all the trophoblast's invasiveness is tamed and "turned off" the very same day the developing infant's pancreas begins to make digestive enzymes, pancreatic digestive enzymes can also "turn off" the growth and invasiveness of many cancers. And as the book's subtitle says, this little-known therapy may very well be "One solution to the medical enigma of our time." Thanks so much to Drs. Gonzalez and Isaacs for bringing us the complete, well-documented explanation!
---j v wright md
tahoma clinic
renton, washington
But if it isn't common, why am I bringing it up? Especially since many of you are done having babies and raising your families? Well, according to some very recent research, it appears that this very specific type of "women's cancer" may actually hold the key to curing many other cancers--in both men and women.
In their new book, The Trophoblast and the Origins of Cancer, Drs. Nicholas Gonzalez and Linda Isaacs reveal that many cancers in both men and women invade surrounding tissue in the exact same way that choriocarcinomas do, using the exact same bio-chemical pathways, signaling molecules, and enzymatic processes.
In 2007, one prominent research group wrote: "Trophoblast research over the past decades has underlined the striking similarities between the proliferative, migratory and invasive properties of placental cells and those of cancer cells. This review recapitulates the numerous key molecules, proto-oncogenes, growth factors, receptors, enzymes, hormones, peptides and tumour-associated antigens (TAAs) expressed by both trophoblastic and cancer cells."
And in an even earlier publication, another group of researchers wrote: "There are striking similarities present between the behavior of invasive placental cells and that of invasive cancer cells. In this review, we propose that cellular mechanisms used by the cells of the placenta during implantation are reused by cancer cells to invade and spread within the body."
So what can we do with this information? Cure cancer, that's what! In fact, it's been done before.
As Drs. Gonzalez and Isaacs report, a Scottish embryologist by the name of Dr. John Beard pioneered this cancer treatment in 1905--more than 100 years ago.
Using only microscopes and none of the "high-tech" instrumentation of the late 20th and early 21st centuries, Dr. Beard observed the uncanny similarities between the growth of the trophoblast (remember, that's the name for the still-developing placenta) and the growth and development of "regular" cancers. But Beard went much further than that.
He reasoned that since 99.99 percent (or more) of all human trophoblasts "switch off" their invasiveness, and morph into mature placentas, possibly the same "switch off"--whatever it might be--could be applied to "regular" cancers. Dr. Beard finally found that "off switch" in the pancreas of the developing baby.
In humans and every mammalian species he studied, the very same day the baby's pancreas first started to secrete digestive enzymes (particularly trypsinogen, trypsin, and chymotrypsin, but also amylase, lipase, elastase, and many others), the invasiveness of the trophoblast began to switch off and it rapidly changed into a mature placenta.
So Dr. Beard did the obvious thing: He injected pancreatic enzymes into animals with cancer--and found that it had a strong anti-cancer effect.
In 1911, he published a book about his observations, The Enzyme Treatment of Cancer. Having heard or read of Dr. Beard's work, many other physicians successfully treated patients with cancer using injectable pancreatic enzymes. In their new book, Drs. Gonzalez and Isaacs point to several reports about these successes published between 1906 and1908, including two published in the Journal of the American Medical Association (JAMA) and the British Medical Journal (BMJ).
So whatever happened to this carefully researched, successful and entirely natural cancer treatment pioneered more than a century ago? For once, it wasn't los Federales--at least, not in the beginning.
The FDA didn't get around to outlawing injectable pancreatic enzymes until 1966. As Drs. Gonzalez and Isaacs explain, there were at least two other major factors that explain why Dr. Beard's cancer treatment didn't catch on.
One was tremendous opposition from "organized medicine." As is so often the case in medicine and other so-called "learned professions," "what you're not up on, you're down on." So medical journals wrote editorials against him, and numerous professors gave lectures denouncing his findings and procedures.
The other even more significant factor was the extremely variable quality of available injectable pancreatic enzyme preparations. At the time, many of them were so poor that they were worthless in cancer therapy. So the lack of results from their use were cited as "proof" that pancreatic enzymes didn't work at all.
But the naysayers weren't loud enough to get everyone to stop using this therapy. One St. Louis doctor reported success treating advanced cancer patients with injectable pancreatic enzymes in the 1920s and 1930s. And in the 1950s, Dr. Frank Shively, a surgeon practicing in Dayton, Ohio, started giving a single pancreatic enzyme--trypsin--by intravenous injection to terminal, inoperable cancer patients. By 1966, he'd given 1,305 injections of pancreatic enzymes (by then he'd also included pepsinogen, desoxyribonuclease and ribonuclease) to 193 terminal cancer patients without adverse reactions.
But by the 1960s, the cancer chemotherapy industry had really taken off. And that's when los Federales stepped in. In 1966, the FDA ordered Dr. Shively--and everyone else using this treatment--to stop giving injectable pancreatic enzymes to cancer patients. So any possible competition to the cancer chemotherapy industry from injectable pancreatic enzymes was stopped before it could get started.
Fortunately, at about the same time, a Texas orthodontist--William Donald Kelley--decided to treat his own cancer with (among other things) large doses of pancreatic digestive enzymes taken orally. As Drs. Gonzalez and Isaacs explain, Dr. Kelley knew nothing of Dr. Beard, but took the enzymes because his own digestive function was so bad. The more enzymes he took, the more his cancer shrank. Combining the enzymes with individualized diet plans, multiple supplements, and detoxification procedures including coffee enemas, Dr. Kelley cured not only his own cancer, but eventually helped cure many others as well.
In the early 1980s, Dr. Gonzalez studied thousands of Dr. Kelley's records and interviewed hundreds of his patients, and found that these treatments worked in a significant number of cases.
After learning thoroughly about Dr. Kelley's approach and the success his patients had experienced, Dr. Gonzalez opened his own cancer-treatment practice in New York City using many of the same principles. Suzanne Somers' 2009 book Knockout: Interviews with Doctors Who Are Curing Cancer and How to Prevent Getting it in the First Place features an extensive interview with Dr. Gonzalez as well as interviews with several of the cancer survivors he's successfully treated.
Let's finish by summarizing Trophoblast. All of its discussion and meticulous documentation is very important-- particularly for medical professionals--but it really all boils down to this: Very many cancers invade surrounding tissues and grow and metastasize using exactly the same mechanisms used by the precursor of the placenta (the trophoblast). And just as all the trophoblast's invasiveness is tamed and "turned off" the very same day the developing infant's pancreas begins to make digestive enzymes, pancreatic digestive enzymes can also "turn off" the growth and invasiveness of many cancers. And as the book's subtitle says, this little-known therapy may very well be "One solution to the medical enigma of our time." Thanks so much to Drs. Gonzalez and Isaacs for bringing us the complete, well-documented explanation!
---j v wright md
tahoma clinic
renton, washington
48 of 48 people found the following review helpful
By SAL
Format:Paperback
This incredibly valuable and inspiring book traces the work of the English embryologist Dr. John Beard, M.D., whom in 1906 proposed that pancreatic proteolytic enzymes could represent the body's main defense against cancer and could be useful as an effective treatment for all types of cancer. Beard recognized that it was probably the fetal source of pancreatic enzymes in particular (the enzymes responsible for regulating differentiation in the fetus), and developed a complete model of carcinogenesis and its prevention and treatment based upon the trophoblastic pancreatic enzyme mechanism.
During the first twenty years of the 20th century, Dr. Beard's work attracted some attention in academic circles. Several case reports exist in the medical literature documenting tumor regression and even remission in terminal cancer patients treated with proteolytic enzymes by practitioners other than Beard. In 1911, Dr. Beard published The Enzyme Therapy of Cancer, which summarized his cancer therapy and supporting evidence. After Beard's death in 1923, the enzyme therapy was largely forgotten. However, periodically, alternative medicine practitioners have rediscovered Dr. Beard's work over the years, and have used pancreatic proteolytic enzymes as a treatment for cancer.
Dr. Gonzalez and Dr. Isaacs have done an outstanding job presenting this material. It's a compelling biochemical drama with powerful insights and is wonderfully written. The stem cell connections are thrilling. It's a treat to read this book and to see the brilliance Beard applied over 100 years ago. This is an amazing piece of work. Highly recommended for anyone passionate about alternative medicine.
Stephen Levine, Ph.D.
During the first twenty years of the 20th century, Dr. Beard's work attracted some attention in academic circles. Several case reports exist in the medical literature documenting tumor regression and even remission in terminal cancer patients treated with proteolytic enzymes by practitioners other than Beard. In 1911, Dr. Beard published The Enzyme Therapy of Cancer, which summarized his cancer therapy and supporting evidence. After Beard's death in 1923, the enzyme therapy was largely forgotten. However, periodically, alternative medicine practitioners have rediscovered Dr. Beard's work over the years, and have used pancreatic proteolytic enzymes as a treatment for cancer.
Dr. Gonzalez and Dr. Isaacs have done an outstanding job presenting this material. It's a compelling biochemical drama with powerful insights and is wonderfully written. The stem cell connections are thrilling. It's a treat to read this book and to see the brilliance Beard applied over 100 years ago. This is an amazing piece of work. Highly recommended for anyone passionate about alternative medicine.
Stephen Levine, Ph.D.
39 of 39 people found the following review helpful
By J.R.
Format:Paperback
Dr. Gonzalez and Dr. Isaacs are "making cancer history" for the average reader with the publishing of "The Trophoblast and the Origins of Cancer". They write so clearly that even a layman can follow the medical side of the cause of cancer, the treatment and why it works. Finally, they have pulled it all together in one book (only 220 pages) with the potential to cause a seismic shift in the public's understanding of cancer and its treatment. Dr. Beard's scientific research from over 100 years ago points the way.
How timely for Dr. Gonzalez, a medical Immunologist, to deliver a positive message about the treatment of cancer. The overall success rate for the treatment of cancer is now estimated to be essentially the same as it was 50 years ago.
Do not let the word Trophoblast frighten you away from this book. It is the pseudo-malignant "precursor" to the placenta and it only exists in the body in that form for a short time. Nevertheless, it has all the characteristics of cancer. Its transformation into normal tissue is what this book is all about.
For many decades, the teaching medical schools have recognized trophoblast as the "precursor" to the placenta and also that the change occurs in the first trimester of pregnancy. They have consistently said they do not know why. Again, the why is what this book is all about.
The medical language in this book is a lot less daunting if you just remember there are two important precursors. The first one is the trophoblast. The second one is the inactive trypsinogen which is the precursor form of the enzyme in the pancreas that converts to trypsin when it is secreted into the intestine.
Remember that word "Trypsin"! It may be as important to cancer as "Insulin" is to diabetes. Diabetes was a death sentence until the pancreas gave up its secret of insulin. So the central message in this book is not a strange phenomenon without precedent.
What is not in dispute in all of medicine is that the trophoblast is a highly invasive tumor-like tissue that transforms at some predetermined point into a non-proliferating, non-aggressive mature placenta. This great mystery of going from "malignant" to "benign" has at least one solution to this medical enigma.
How timely for Dr. Gonzalez, a medical Immunologist, to deliver a positive message about the treatment of cancer. The overall success rate for the treatment of cancer is now estimated to be essentially the same as it was 50 years ago.
Do not let the word Trophoblast frighten you away from this book. It is the pseudo-malignant "precursor" to the placenta and it only exists in the body in that form for a short time. Nevertheless, it has all the characteristics of cancer. Its transformation into normal tissue is what this book is all about.
For many decades, the teaching medical schools have recognized trophoblast as the "precursor" to the placenta and also that the change occurs in the first trimester of pregnancy. They have consistently said they do not know why. Again, the why is what this book is all about.
The medical language in this book is a lot less daunting if you just remember there are two important precursors. The first one is the trophoblast. The second one is the inactive trypsinogen which is the precursor form of the enzyme in the pancreas that converts to trypsin when it is secreted into the intestine.
Remember that word "Trypsin"! It may be as important to cancer as "Insulin" is to diabetes. Diabetes was a death sentence until the pancreas gave up its secret of insulin. So the central message in this book is not a strange phenomenon without precedent.
What is not in dispute in all of medicine is that the trophoblast is a highly invasive tumor-like tissue that transforms at some predetermined point into a non-proliferating, non-aggressive mature placenta. This great mystery of going from "malignant" to "benign" has at least one solution to this medical enigma.
Most Recent Customer Reviews
5.0 out of 5 stars
excellent
well worth a read, wish more people could have access to this one, will provide a copy to our library system,
Published 2 months ago by bernard john christensen
5.0 out of 5 stars
Scientific genius
Never in my life did I read such a comprehensive scientific report. Dr. Beard stands for the ultimate example of accuracy and insight. Read more
Published 13 months ago by Filip Otten
4.0 out of 5 stars
trophoblast cancer book
Does not read as half-baked. Well researched and in depth. Two parts ~ the first methodically taking you through embriology and placental attachment protocals and genetic cells'... Read more
Published 16 months ago by malell
5.0 out of 5 stars
Great Resource
It comes as no surprise that there are multiple theories as to the origin of cancer: this one truly holds water. Read more
Published 17 months ago by Robert Feller
5.0 out of 5 stars
Worthy of a Nobel Prize
Dr. Nicholas J. Gonzales has demonstrated the origin of cancer from undifferentiated germ cells, which we today call adult stem cells, and he has shown how the uncontrolled growth... Read more
Published on January 24, 2011 by Tore Fossum
5.0 out of 5 stars
Riveting
I won't discuss the subject matter of this highly stimulating work; others have done so already. As a medical writer however, I find this one of the top 5 books I have ever had the... Read more
Published on December 16, 2010 by C. Falcone
5.0 out of 5 stars
"NEW" CANCER SCIENCE "OLD"
This extraordinary and long overdue book describes the extensive scientific bases for and history of use of pancreatic enzymes to control cancer--from the work of English scientist... Read more
Published on November 7, 2010 by PaP, Ph.D.
5.0 out of 5 stars
Cancer as a Birth Like Process
This book provides important information on how a cancer is formed based on the early research of that Scottish biologist Dr. Read more
Published on October 6, 2010 by Alex Brown, Jr
5.0 out of 5 stars
Gonzalez Books As Important As Origin of the Species
I just finished reading the companion cancer books by Dr. Nicholas Gonzalez, MD. Book one, The TROPHOBLAST and the ORIGINS OF CANCER by Gonzalez and Linda Isaacs, MD, provides... Read more
Published on August 11, 2010 by Owen R. Fonorow
5.0 out of 5 stars
Science of Cancer and Health
The name Nicholas J. Gonzalez, M.D., one hundred years from now, will be in medical history books. Authors will marvel that he was able to save the lives of cancer patients when... Read more
Published on March 10, 2010 by Priscilla Petty
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