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The Trophoblast and the Origins of Cancer: One solution to the medical enigma of our time Paperback – 2009

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This groundbreaking analysis reveals how more than 100 years ago, the English scientist Dr. John Beard uncovered not only the likely origins of cancer but also its solution. Dr. Gonzalez explains Dr. Beard's underlying theory and explores Dr. Beard's pioneering use of pancreatic enzymes for cancer treatment. This book also showcases case histories describing cancer patients successfully treated with pancreatic enzymes by the authors. Dr. Beard's achievements, though unappreciated in his own day, are many. A research embryologist by training, he proposed that the early mammalian placenta, or trophoblast, the connection between the embryo and the maternal uterine blood supply, represents an ideal model for the study of malignancy. In its ability to divide rapidly, invade maternal tissues, and generate a blood supply, the trophoblast, Beard reasoned, initially behaves as any growing tumor might. However, the trophoblast differs from malignancy, Beard stated, because at some predetermined point it changes from an invasive tissue into the non-aggressive placenta, necessary for early embryonic life. Beard spent years searching for the key to this remarkable transformation, ultimately discovering that the very day the trophoblast changes character, the embryonic pancreas begins secreting large amounts of enzymes. Beard then proposed that since pancreatic enzymes regulate trophoblast growth, they must represent our main defense against cancer. Subsequently, in animal experiments and in clinical use with human cancer patients, Beard demonstrated pancreatic enzymes could attack and destroy cancerous tumors. In this book, you will read of Dr. Beard's discoveries, and how modern science confirms much of what he long ago proposed. Along the way, you will learn that Dr. Beard discovered stem cells, the focus of much research effort today, though he never received proper credit. And you will see that Dr. Beard may have uncovered the key to the deadly disease of cancer.


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Product Details

  • Paperback: 220 pages
  • Publisher: New Spring Press (2009)
  • Language: English
  • ISBN-10: 0982196504
  • ISBN-13: 978-0982196502
  • Product Dimensions: 9.9 x 6.9 x 0.5 inches
  • Shipping Weight: 1.2 pounds
  • Average Customer Review: 4.9 out of 5 stars  See all reviews (19 customer reviews)
  • Amazon Best Sellers Rank: #289,826 in Books (See Top 100 in Books)

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103 of 103 people found the following review helpful By J. V. Wright on June 19, 2010
Format: Paperback
It's not extremely common, so unless you're a health care professional or student, you've likely never heard or read of "choriocarcinoma." This invasive and often metastasizing cancer usually originates in the beginnings of a placenta. A choriocarcinoma starts out as all placentas do, as a tissue called "trophoblast" rapidly invading the lining of the uterus. But instead of "switching off" it's invasiveness once it's established, and turning into a mature placenta to nourish the developing infant, a the ever-invading trophoblast--now called a choriocarcinoma--just keeps invading and invading. If it isn't stopped, it will metastasize just like any other cancer--and ultimately kill it's "host."

But if it isn't common, why am I bringing it up? Especially since many of you are done having babies and raising your families? Well, according to some very recent research, it appears that this very specific type of "women's cancer" may actually hold the key to curing many other cancers--in both men and women.

In their new book, The Trophoblast and the Origins of Cancer, Drs. Nicholas Gonzalez and Linda Isaacs reveal that many cancers in both men and women invade surrounding tissue in the exact same way that choriocarcinomas do, using the exact same bio-chemical pathways, signaling molecules, and enzymatic processes.

In 2007, one prominent research group wrote: "Trophoblast research over the past decades has underlined the striking similarities between the proliferative, migratory and invasive properties of placental cells and those of cancer cells. This review recapitulates the numerous key molecules, proto-oncogenes, growth factors, receptors, enzymes, hormones, peptides and tumour-associated antigens (TAAs) expressed by both trophoblastic and cancer cells.
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57 of 57 people found the following review helpful By SAL on January 27, 2010
Format: Paperback
This incredibly valuable and inspiring book traces the work of the English embryologist Dr. John Beard, M.D., whom in 1906 proposed that pancreatic proteolytic enzymes could represent the body's main defense against cancer and could be useful as an effective treatment for all types of cancer. Beard recognized that it was probably the fetal source of pancreatic enzymes in particular (the enzymes responsible for regulating differentiation in the fetus), and developed a complete model of carcinogenesis and its prevention and treatment based upon the trophoblastic pancreatic enzyme mechanism.

During the first twenty years of the 20th century, Dr. Beard's work attracted some attention in academic circles. Several case reports exist in the medical literature documenting tumor regression and even remission in terminal cancer patients treated with proteolytic enzymes by practitioners other than Beard. In 1911, Dr. Beard published The Enzyme Therapy of Cancer, which summarized his cancer therapy and supporting evidence. After Beard's death in 1923, the enzyme therapy was largely forgotten. However, periodically, alternative medicine practitioners have rediscovered Dr. Beard's work over the years, and have used pancreatic proteolytic enzymes as a treatment for cancer.

Dr. Gonzalez and Dr. Isaacs have done an outstanding job presenting this material. It's a compelling biochemical drama with powerful insights and is wonderfully written. The stem cell connections are thrilling. It's a treat to read this book and to see the brilliance Beard applied over 100 years ago. This is an amazing piece of work. Highly recommended for anyone passionate about alternative medicine.

Stephen Levine, Ph.D.
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48 of 48 people found the following review helpful By J.R. on February 8, 2010
Format: Paperback
Dr. Gonzalez and Dr. Isaacs are "making cancer history" for the average reader with the publishing of "The Trophoblast and the Origins of Cancer". They write so clearly that even a layman can follow the medical side of the cause of cancer, the treatment and why it works. Finally, they have pulled it all together in one book (only 220 pages) with the potential to cause a seismic shift in the public's understanding of cancer and its treatment. Dr. Beard's scientific research from over 100 years ago points the way.

How timely for Dr. Gonzalez, a medical Immunologist, to deliver a positive message about the treatment of cancer. The overall success rate for the treatment of cancer is now estimated to be essentially the same as it was 50 years ago.

Do not let the word Trophoblast frighten you away from this book. It is the pseudo-malignant "precursor" to the placenta and it only exists in the body in that form for a short time. Nevertheless, it has all the characteristics of cancer. Its transformation into normal tissue is what this book is all about.

For many decades, the teaching medical schools have recognized trophoblast as the "precursor" to the placenta and also that the change occurs in the first trimester of pregnancy. They have consistently said they do not know why. Again, the why is what this book is all about.

The medical language in this book is a lot less daunting if you just remember there are two important precursors. The first one is the trophoblast. The second one is the inactive trypsinogen which is the precursor form of the enzyme in the pancreas that converts to trypsin when it is secreted into the intestine.

Remember that word "Trypsin"! It may be as important to cancer as "Insulin" is to diabetes.
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