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The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries
 
 
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The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries [Hardcover]

Shannon Moffett (Author)
4.8 out of 5 stars  See all reviews (8 customer reviews)

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Book Description

January 20, 2006
The average human brain weighs three pounds—80 percent of which is water—and yet it's capable of outstripping the computational and storage capacities of the most complex computer. But how the mind works remains one of humankind's greatest mysteries.

With boundless curiosity and enthusiasm, Shannon Moffett, a Stanford medical student, takes us down the halls of neuroscience to the front lines of cutting-edge research and medicine to meet some of today's most extraordinary scientists and thinkers, all grappling with provocative questions: Why do we dream? How does memory work? How do we see? What happens when we think?

Each chapter delves into a different aspect of the brain, following the experts as they chart new ground. Moffett takes us to a lab where fMRI scans reveal the multitude of stimuli that our brains unconsciously take in; inside an operating room where a neurosurgeon removes a bullet from a patient's skull; to the lab of Christof Koch, a neuroscientist tracking individual neurons in order to crack the code of consciousness; and to a research lab where scientists are investigating the relationship between dreams and waking life. She also takes us beyond the scientific world—to a Zen monk's zendo, where she explores the effects of meditation on the brain; inside the home of a woman suffering from dissociative identity disorder; to a conference with the philosopher Daniel Dennett, who uses illusions, magic, tricks, and logic to challenge our assumptions about the mind; and to the home of the late Nobel Laureate Francis Crick, co-discoverer with James Watson of DNA's double-helix structure.

Filled with fascinating case studies and featuring a timeline that tracks the development of the brain from conception to death, The Three Pound Enigma is a remarkable exploration of what it means to be human.

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Editorial Reviews

From Publishers Weekly

Can the complexities of the human mind be located in a physical organ? Where do our memories and our selves go when the brain dies? In her first book, Stanford medical student Moffett ponders these and other perennial questions through a series of pedestrian profiles of scientists and philosophers, among others. Moffett introduces us to neurosurgeon Roberta Glick, whose work offers a glimpse of the frailty of the human brain and the fact that even minor physical damage to it can whisk away our consciousness and memory forever. Other profiles include John Gabrieli, whose pioneering work with functional MRIs has led to new discoveries about how memory works; sleep researcher Bob Stickgold, who uses functional MRIs and virtual-reality games in an attempt to capture the operation of consciousness in the dream state; and Zen monk Norman Fischer, who teaches Moffett, through meditation, that mind and brain are not synonymous. While the profiles offer no new insights into the mystery of the human brain, Moffett sandwiches in fascinating interludes tracing the development of the brain from embryonic state to death. The interludes sometimes contain overly technical language, but they offer an instructive look at the brain. Line art. Main Selection of the Scientific American Book Club.(Jan. 20)
Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.

About the Author

Shannon Moffett graduated from NYU with a B.A. She is currently a medical student at Stanford University School of Medicine, where she’s received two Stanford Arts and Humanities Medical Scholars grants. This is her first book.

Product Details

  • Hardcover: 304 pages
  • Publisher: Algonquin Books; 1ST edition (January 20, 2006)
  • Language: English
  • ISBN-10: 1565124235
  • ISBN-13: 978-1565124233
  • Product Dimensions: 9.2 x 6.3 x 1.2 inches
  • Shipping Weight: 1.3 pounds (View shipping rates and policies)
  • Average Customer Review: 4.8 out of 5 stars  See all reviews (8 customer reviews)
  • Amazon Best Sellers Rank: #970,075 in Books (See Top 100 in Books)

More About the Author

An emergency physician who can't stop thinking, Moffett currently lives in Shanghai, China, where her two extremely American kids are attending first grade in a local Chinese school--an experience stranger than anything she's ever seen in the ER.

http://tworedscarves.com

 

Customer Reviews

8 Reviews
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Average Customer Review
4.8 out of 5 stars (8 customer reviews)
 
 
 
 
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26 of 26 people found the following review helpful:
4.0 out of 5 stars a guided tour of tomorrow's brain science, for beginners and experts alike, March 31, 2006
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This review is from: The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries (Hardcover)
How does "the mind" emerge from the brain? We are closer to a coherent answer than ever before, thanks to accumulating evidence from a variety of fields - including cognitive neuroscience, clinical psychology, internal medicine, somnology, and even modern philosophy. In "The Three Pound Enigma", Shannon Moffett explores the cutting-edge of these disciplines, literally: from the risky operation by neurosurgeon Roberta Glick described in the first chapter, to penetrating theoretical discussions with the sharpest researchers around (including vision scientist Christof Koch and philosopher Daniel Dennett), this book provides a cross-section of current brain research.

Unlike so many popular science books, "The Three Pound Enigma" has something for novices and experts alike. Clear explanations of everything from fMRI technology & K-complexes to anterograde amnesia & dissociative identity disorders will dazzle the layperson, and yet Moffett also provides something for the professional audience: a glimpse into the personalities of some of the field's most successful scholars, sufficiently detailed to give additional insight on their (in)famous theoretical perspectives.

For example, although many can lay claim to having late-night conversations about consciousness, very few (other than Moffett, and her readers) have had such a conversation in a crowded Memphis nightclub with renowned consciousness philosopher Daniel Dennett. Or, perhaps a better example may be the anecdotes related by somnologist Robert Stickgold, who traces his career from undergraduate neurobiology research at Harvard, to a stint as a computer programmer, first on Wall Street ... and then in one of the country's preeminent sleep labs. Or, better yet, Moffett gives fascinating context to one of the most unlikely collaborations in modern neuroscience: that between red-haired iconoclast Christof Koch and the late Francis Crick, a 1962 Nobel Laureate and the co-discoverer of DNA's double-helix structure.

Between clever quips (e.g., cognitive neuroscience: the expensive branch of philosophy) and penetrating insights about the current state of brain research, Moffett also includes "interludes," each of which documents a different stage in cognitive development, from conception to death. Although these sections are not tightly integrated with the text, they're useful grounding for both neuro-novices and experts alike. There's even a good deal of freely available web content, available for those who want to delve a little deeper into the topics discussed in the book.

In summary, Shannon Moffett's book is a wonderful introduction to the ideas underlying modern brain research, as well as a revealing portrait of several of the individuals driving these developments. The book comes highly recommended to laypeople with an interest in learning more about major players in brain research, and even to more experienced readers who desire a more personal view of the biggest names in the field.
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6 of 6 people found the following review helpful:
5.0 out of 5 stars An excellent research-and-literature-review on the problem of brain and consciousness, February 24, 2007
This review is from: The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries (Hardcover)
This is a most readable review of the work and praxis of front line researchers and writers on the subject of the relationship between brain and consciousness. It was a great experience to read this book especially while trying to read simultaneuously the much more detailed and specific book by Christopher Koch. Both readings illuminated each other. The recently deceased Francis Crick comes into a splendid light.
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10 of 13 people found the following review helpful:
5.0 out of 5 stars INCREDIBLE BOOK about an INCREDIBLE ORGAN of the Body, March 9, 2006
This review is from: The Three-Pound Enigma: The Human Brain and the Quest to Unlock Its Mysteries (Hardcover)
Not to mention that the author wrote this book WHILE she was in medical school. She became enamored, if that's a good word, maybe fascinated, curious, are better words, when she took the Gross Anatomy class. She had to open up the face of the cadaver she was studying and her life has never been the same once she started to learn about the brain. She provides some historic perspective about what was previously thought about the brain and now what is known and what still needs to be known. She also relates the biochemistry of the brain to personality and mental illness.




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Inside This Book (learn more)
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
fusiform gyrus, nondeclarative memory, electrical difference, mental place
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Francis Crick, United States, Cook County, Judy Castelli, Roberta Glick, Bill Clinton, Christof Koch, John Gabrieli, Adolescence Adulthood Old Age Death Birth, Cartesian Theater, Daniel Dennett, Gravelly Voice, Mapping the Field, Mary Reynolds, Consciousness Explained, Lucas Center, New York Times, Nobel Prize, Darth Vader, Fort Bragg, Matt Kirschen, Uri Geller, Zen Buddhism
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