Transport and Trafficking in the Malaria-Infected Erythrocyte - No. 226 [Hardcover]

Novartis Foundation (Author)

Book Description

ISBN-10: 0471998931 | ISBN-13: 978-0471998938 | Publication Date: January 11, 2000 | Edition: 1

There is an urgent need to uncover new therapies that will protect against malaria, as the parasite becomes increasingly resistant to available drugs and this book offers insights into three interrelated aspects of the malaria-infected erythrocyte:

* The transport of solutes into and out of the infected cell and the use of specific trafficking pathways in drug targeting

* The traffic of proteins produced by the intracellular parasite as an essential process for the biogenesis of transport systems.

* The relationship between the transport of drugs into the infected cell and the mode of drug action and drug resistance.

Editorial Reviews

Review

"...an excellent reference work for those in the field..." (Cell Biology International, Vol.26, No. 4, 2002)

From the Back Cover

Malaria is a major infectious disease, affecting 500 million people and causing the death of around two million people each year. As the parasite becomes resistant to available drugs there is an urgent need to uncover new therapies that will protect against and cure this debilitating and fatal disease. Knowledge of specific physiological and biochemical processes in the malaria-infected erythrocyte could provide a basis for the development and targeting of such drugs. This book offers insights into three interrelated aspects of the malaria-infected erythrocyte:

• The transport of solutes into and out of the infected cell and the use of specific trafficking pathways in drug targeting.
• The traffic of proteins produced by the intracellular parasite as an essential process for the biogenesis of transport systems.
• The relationship between the transport of drugs into the infected cell and the mode of drug action and drug resistance.

Product Details

• Hardcover: 304 pages
• Publisher: Wiley; 1 edition (January 11, 2000)
• Language: English
• ISBN-10: 0471998931
• ISBN-13: 978-0471998938
• Product Dimensions: 9.4 x 6.2 x 0.8 inches
• Shipping Weight: 1.3 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #5,076,902 in Books (See Top 100 in Books)