First Sentence:
Despite rapid development in the therapeutic management of mood disorders, with the introduction of new classes of antidepressants and mood stabilizers since the 1980s, in clinical practice the problem of treatment resistance continues to occupy a considerable amount of the physician's time.
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Key Phrases - Statistically Improbable Phrases (SIPs):
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treating resistant depression, antiglucocorticoid treatment, antiglucocorticoid drugs, direct stimulant therapy, secondary mood disorders, resistant mood disorders, refractory depression, thyroid augmentation, adequate antidepressant treatment, lithium augmentation, primary antidepressants, mood disorder patients, lithium potentiation, adequate antidepressant trial, personality disorder comorbidity, anterior paralimbic structures, poststroke patients, triiodothyronine augmentation, primary mood disorders, second antidepressant, tricyclic nonresponders, washout studies, treatment resistance, cycling bipolar affective disorder, medication resistance
Key Phrases - Capitalized Phrases (CAPs):
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American Journal of Psychiatry, Journal of Clinical Psychiatry, Archives of General Psychiatry, Biological Psychiatry, British Journal of Psychiatry, New York, Journal of Affective Disorders, Journal of Clinical Psychopharmacology, American Psychiatric Association, Psychiatry Research, Acta Psychiatrica Scandinavica, Journal of the American Medical Association, New England Journal of Medicine, Raven Press, Psychiatric Clinics of North America, Psychological Medicine, American Psychiatric Press, Canadian Journal of Psychiatry, Psychopharmacology Bulletin, Brain Research, British Medical Journal, John Wiley, Guilford Press, International Clinical Psychopharmacology, Journal of Neurology
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