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22 of 22 people found the following review helpful:
5.0 out of 5 stars
Great product -- PLEASE CONSULT YOU DOCTOR, August 7, 2010
This review is from: Twinlab Niacin (B-3) 1000mg, 100 Capsules (Pack of 3) (Health and Beauty)
I have been using this product for a year after switching from GNC's niacin (B3). GNC's product was good, but very expensive. I no longer experience the "Niacin Flush" that people are complaining about.
Before taking any megadose supplement/vitamin, you should CONSULT YOUR DOCTOR. Taking large doses of vitamin B3 (niacin) requires you to have good liver function. If your liver function is poor, you could permanently damage it. My doctor specifically told me to STAY AWAY FROM THE "NO-FLUSH" NIACINAMIDE.
Niacin, vitamin B3 has been recommended for raising your HDL and lowering your LDL blood levels. The ratio of HDL to LDL has been linked with heart health. My doctor also recommended having 1-2 alcoholic beverages a day to help bolster the good effect. The doctors don't yet really understand how this all works, but the data is pretty convincing. Having more than 2 alcoholic beverages a day is counterproductive to heart health.
Your doctor should tell you that a "niacin flush" and itching are very common side effects that you may experience. That is why the doctor will tell you to start with a small ~100mg dose and then slowly work your way up to the 1,000mg dose. This gradual buildup will help keep your immune system from launching the very uncomfortable itching and blotchy rash "hives". Some have described it as being similar to a hot flash.
Once you build up to the therapeutic dosage, your body will recognize that the niacin is not going away, and will eventually stop or greatly reduce its response.
I hope this review helps some people to realize that taking megadoses of niacin should be taken with an informed consent, and the green light from your doctor.
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22 of 22 people found the following review helpful:
5.0 out of 5 stars
Better than prescription drugs, September 9, 2007
Niacin is better than prescription drugs for improving your HDL/LDL cholesterol ratio, and has far fewer serious side effects. This particular brand of niacin is probably no better or worse than any other brand, but the 1000 mg capsules are more convenient than taking numerous smaller capsules.
Yes, flushing can be a very annoying side effect with large doses of niacin but it is not life or health threatening and it can be managed. Here are the steps, in order of importance, to control flushing:
1. Make sure your body is fully hydrated before taking niacin, i.e don't take it while dehydrated.
2. Work up to the desired dose. Start with a small dose, maybe 500 mg, and work up to 2,000 or 3,000 mg.
3. It is best not to take niacin on an empty stomach.
4. Take a baby aspirin 1/2 hour before taking niacin.
**** This is the obligatory consult your doctor warning. At large doses, niacin is more like a drug than a vitamin supplement. As with many drugs, there is a small possibility of liver damage. This should be monitored with periodic blood test.
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15 of 15 people found the following review helpful:
5.0 out of 5 stars
Great Product/Great Service, March 28, 2009
This review is from: Twinlab Niacin (B-3) 1000mg, 100 Capsules (Pack of 3) (Health and Beauty)
I agree that Niacin is much better than prescription drugs for improving your HDL/LDL cholesterol and has fewer serious side effects. My MD recommended it for me and cautioned me to build up gradually. Starting at 250 and working my way up slowly to 1500 mg. of Niacin (Not Flush Free or Time Released) brought all of my levels into recommended ranges in only 6 months. This is probably not typical, but it was great. I then changed to another brand I got on sale. It was the Flush Free / Time Released. My next round of blood work found my HDL/LDL creeping back in to the "red zones". So, I tossed the Flush Free when my order of this product arrived. I took two the first night & experienced the 2 hour flush that the one star rater noted. Very, Very uncomfortable. It made me realize that I again needed to build up to my old dose. I am doing that now and I am convinced that in 6 mos. my HDL/LDL levels will be back where they are supposed to be. For me, the Flush Free did not work on my HDL/LDL levels. Build up slowly with the regular Niacin. I had to go back to my 250 mg & I am now @ 400. In a few weeks I'll be at 1000 mg. working back to my 2000 mg. Also, the service was very fast! I'll re-order from them again.
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