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Understanding DNA: The Molecule & How It Works
 
 

Understanding DNA: The Molecule & How It Works [Paperback]

C.R. Calladine (Author), Horace R. Drew (Author)
4.0 out of 5 stars  See all reviews (2 customer reviews)


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Understanding DNA, Second Edition: The Molecule and How It Works Understanding DNA, Second Edition: The Molecule and How It Works 4.0 out of 5 stars (2)
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Book Description

0121550869 978-0121550868 November 1992
The functional properties of any molecule are directly related to and affected by its structure. This is no less true for DNA, the molecule that carries the code for our very being. Yet, so often DNA is thought of as just a string of bases. "Understanding DNA" explains in a step by step fashion why DNA forms specific structures, the nature of these structures and how they fundamentally effect the biological processes of transcription, recombination and replication. Containing over 100 illustrations, some in full colour, "Understanding DNA" describes the basic units of DNA and how these form the double helix; characterizes the various types of DNA double helix that exist; explains how and why DNA twists and curves; discusses the mechanisms of DNA supercoiling; summarizes the assembly of DNA and protein into chromosomes; outlines the principles of the methods employed to study DNA structure; contains simple exercises, further reading and a bibliography at the end of each chapter.


Editorial Reviews

Review

Throughout the book, there is something of a playful spirit at work...[which] make[s] subtle physical effects...intuitively comprehensible. We see DNA structures so often that it is often taken for granted that the molecule should not be anything but an aesthetically appealing, spiralling helix. But why should it assume such a nice structure? The book offers an absolutely delightful answer to this and other similarly mischievous questions. Understanding DNA is a great bookthat will surely prove to be a valuable teaching tool.
--THE BIOCHEMIST
Among the strengths [of the book] are the clarity of the explanations of some quite difficult concepts and the novel way in which certain ideas are treated, perhaps causing the reader to think again about certain aspects of DNA structure. I enjoyed reading this book and would encourage colleagues working in the general area of DNA research to read it.
--HEREDITY
A systematic and comprehensive analysis of the structure of DNA from a wonderfully fresh perspective. The book is a systematic effort to understand this fascinating molecule from the inside out, building from the first, and simplest, principles...I recommend it very highly.
--TRENDS IN GENETICS
Stylish...beautifully crafted, with a logical step-by-step approach to the subject. A book from which the advanced undergraduate will benefit, and which will also generate a refreshing perspective for experts.
--NATURE --This text refers to an out of print or unavailable edition of this title.

Book Description

An easily comprehendible explaination of the structure and function of DNA. --This text refers to the Hardcover edition.

Product Details

  • Paperback: 251 pages
  • Publisher: Academic Pr (November 1992)
  • Language: English
  • ISBN-10: 0121550869
  • ISBN-13: 978-0121550868
  • Product Dimensions: 9.5 x 6.6 x 0.6 inches
  • Shipping Weight: 15.5 ounces
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (2 customer reviews)
  • Amazon Best Sellers Rank: #3,097,719 in Books (See Top 100 in Books)

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4.0 out of 5 stars It lacks so many parts in comparison to the last edition., November 13, 2011
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This review is from: Understanding DNA: The Molecule & How It Works (Paperback)
It lacks so many parts in comparison to the last edition. I should have compared the chapters' list in the two versions at some place.
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4.0 out of 5 stars Good introduction, October 4, 2010
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This review is from: Understanding DNA: The Molecule & How It Works (Paperback)
Very good introduction to DNA structures and function for undergrads or, in fact, even any non-scientist. It does not, nor does it claim to, go into details, e.g. in depth description of the models or experiments, so if you're looking for that, you'll have to look elsewhere.
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Inside This Book (learn more)
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First Sentence:
One day we were having lunch together at a Cambridge College. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
histone spool, fly polytene chromosomes, protein spools, overall helix axis, toroidal supercoil, unrolled view, propeller twist, partial electric charges, interwound supercoil, normal cytosine, electric power cord, dinucleotide step, methylation enzymes, gel fibers, low twist, roll angles, histone octamer, twist axis, low slide, major groove, polymerase protein, histone proteins, cytosine bases, helical turn, minor groove
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Journal of Molecular Biology, Journal of Biological Chemistry, New York, Genetic Code, Journal of Cell Biology, Nucleic Acids Research, Nature Structural Biology
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