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Understanding the Process of Aging: the Roles of Mitochondria, Free Radicals, and Antioxidants (Oxidative Stress and Disease)
 
 
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Understanding the Process of Aging: the Roles of Mitochondria, Free Radicals, and Antioxidants (Oxidative Stress and Disease) [Hardcover]

Lester Packer (Editor)

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Book Description

0824717236 978-0824717230 January 15, 1999 1st
This innovative reference explores a wide selection of topics associated with aging, providing a solid understanding of the significance and molecular basis of the aging process and charting the course of future research in the area.
Stresses the interplay of mitochondria, mitochondrial DNA, oxidants, and antioxidants!
Featuring the research of over 55 experts in the area, Understanding the Process of Aging
  • covers the functions of nitric oxide and peroxynitrite in mitochondria
  • integrates several views on the role of mitochondria in the development of apoptosis
  • gives a quantitative analysis of mutations of mitochondrial DNA during human aging
  • highlights mitochondrial free radical production
  • introduces new roles of ubiquinone in mitochondrial functions
  • offers new antioxidant-based complementary therapeutic strategies
  • details aspects of intact cells and whole organisms in health and disease
  • and more!
    Featuring over 1800 references, tables, drawings, and photographs, Understanding the Process of Aging benefits nutritionists and dieticians, geriatricians, cell and molecular biologists, chemists and biochemists, pharmacologists, biotechnologists, neurologists, cardiologists, oncologists, dermatologists, and graduate and medical school students in these disciplines.

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    Inside This Book (learn more)
    First Sentence:
    A series of organelles isolated from mammalian organs and other aerobic eukaryotic cells have been described as sources of superoxide radical anion (O2) and hydrogen peroxide (H2O2). Read the first page
    Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
    bioenergetic crisis, cells following oxidative stress, muscle mitochondrial respiratory chain function, ornithine carrier, mitochondrial aging, old mitochondria, acatalasemic mice, aged mitochondria, mitochondrial phosphate carrier, familial mitochondrial encephalomyopathy, ubiquinone biosynthesis, inflammatory gene induction, mitochondrial oxidant generation, protein oxidative damage, lung mitochondria, pyruvate carrier, postmitotic cells, transmembrane processes, translocase deficiency, mitochondrial hypothesis, mitochondrial theory, yeast deficient, mitochondrial production, mitochondrial generation, lipofuscin formation
    Key Phrases - Capitalized Phrases (CAPs): (learn more)
    Biol Chem, Proc Natl Acad Sci, Biochim Biophys Acta, Free Radic Biol Med, Biochem Biophys Res Commun, Arch Biochem Biophys, Mech Ageing Dev, New York, Mutat Res, Bioenerg Biomembr, Cell Biol, Nat Genet, Clin Invest, Exp Med, Physiol Rev, Academic Press, Exp Gerontol, Biochem Mol Biol Int, Brain Res, Free Radic Res, Ann Neurol, Annu Rev Biochem, Cancer Res, Hum Genet, Mol Cell Biochem
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