I recently read the book, 1001 Video Games You Must Play Before You Die. They had a ton of great video games. So it inspired me to make my own.
1) Metal Gear Solid (PS1)
2) Mass Effect (XBOX 360)
3) Half Life (PC)
4) Final Fantasy IX (PS1) Sorry VI & VII but IX is my personal fav!
5) Goldeneye (N64)
6) Super Castlevania 4 (SNES)
7) Chrono Trigger (SNES)
8) Banjo & Kazooie (N64)
9) Legend of Dragoon (PS1)
10) Super Mario Bros 3 (NES)
11) Legend of Zelda: A Link to the Past (SNES)
12) Contra (NES)
13) Star Wars: Jedi Knight, Dark Forces 2
14) Batman Arkham Aslyum (PS3)
15) Grand Theft Auto IV (360)
16) Star Fox 64 (N64)
17) Uncharted 2: Among Thevies (PS3)
18) Robocop vs. The Terminator (Sega Genesis)
19) Dragon Quest VIII: Journey of the Cursed King (PS2)
20) Mortal Kombat (Sega Genesis or Arcade)
While these are some of my top favorite games, they are not in any order. I have much more games, but I wanted to keep it simple. Please post what games you'd suggest people should play before they kick the bucket.