Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine) [Hardcover]

Curtis A. Machida (Editor)

Book Description

Publication Date: October 7, 2002 | ISBN-10: 1588290190 | ISBN-13: 978-1588290199 | Edition: 1

Researchers from academia and biotechnology describe proven molecular methods for the construction, development, and use of virus vectors for gene transfer and gene therapy. Offering detailed step-by-step instructions to ensure successful results, these experts detail the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Additional chapters demonstrate the use of virus vectors in the brain and central nervous system. Comprehensive and highly practical, Viral Vectors for Gene Therapy: Methods and Protocols provides not only researchers with the basic tools needed to design targeted gene delivery vectors, but also clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders.

Editorial Reviews

Review

"This text would be very good for someone who can appreciate the many and varied practical aspects of performing a gene therapy study. I would certainly recommend it to anyone I knew working in the gene therapy field as a book to compare and contrast practical approaches and requirements for various viral vectors." - Pharmaceutical Research

From the Back Cover

The promise of gene therapy can be realized only if workable vectors can be found to deliver therapeutic genes. In Viral Vectors for Gene Therapy: Methods and Protocols, leading researchers from academia and biotechnology describe proven molecular methods for the construction, development, and use of virus vectors for gene transfer and gene therapy. Offering detailed step-by-step instructions to ensure successful results, these experts detail the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Additional chapters demonstrate the use of virus vectors in the brain and central nervous system. Each protocol includes a discussion of the principles involved, numerous charts and tables, ample references, and notes on possible problems, troubleshooting, and alternative procedures. Comprehensive and highly practical, Viral Vectors for Gene Therapy: Methods and Protocols provides not only researchers with the basic tools needed to design targeted gene delivery vectors, but also clinicians with an understanding of how to apply viral vectors to the treatment of genetic disorders.

Product Details

• Hardcover: 608 pages
• Publisher: Humana Press; 1 edition (October 7, 2002)
• Language: English
• ISBN-10: 1588290190
• ISBN-13: 978-1588290199
• Product Dimensions: 9.7 x 5.9 x 1.3 inches
• Shipping Weight: 2 pounds (View shipping rates and policies)
• Amazon Best Sellers Rank: #2,320,332 in Books (See Top 100 in Books)

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