Vitamin K, Volume 78 (Vitamins and Hormones) [Hardcover]

Gerald Litwack (Editor)

Book Description

ISBN-10: 0123741130 | ISBN-13: 978-0123741134 | Publication Date: March 17, 2008 | Edition: 1

First published in 1943, VITAMINS AND HORMONES is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, VITAMINS AND HORMONES continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

KEY FEATURES:

*Focuses on the problem of blood coagulation and hypercoagulability as well as bone metabolism and vascular biology.

*In the category of basic science, contributions cover: VKOR1, the quinone reductases including structure, function and mechanism, vitamin K-dependent carboxylation, the actions of Gas6, vitamin K2-mediated apoptosis and other topics.

*In the category of disease-related subjects, contributions cover warfarin therapy, diabetic nephropathy, bone health, including osteoporosis and tumor cell suppression, as well as other topics.

Editorial Reviews

About the Author

Trained in biochemistry at the University of Wisconsin, Madison, Dr. Litwack worked on enzymology and the effects of hormones on enzyme systems. Then he was a Postdoctoral Fellow of the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. Dr. Litwack's first position was as Assistant Professor of Biochemistry at Rutgers University in 1954. Six years later, he joined the University of Pennsylvania as associate professor and four years later went to the Fels Institute for Cancer Research and Molecular Biology, as full professor, eventually becoming Deputy Director of the Institute. In 1991, he accepted the Chair of Pharmacology at Thomas Jefferson University where he is also Deputy Director of the Jefferson Cancer Institute and Associate Director for Basic Science in the Jefferson Cancer Center. Dr. Litwack's work has been in the area of mechanisms of steroid receptor action involving especially the glucocorticoid and mineralocorticoid receptors, immunophi.

Product Details

• Hardcover: 300 pages
• Publisher: Academic Press; 1 edition (March 17, 2008)
• Language: English
• ISBN-10: 0123741130
• ISBN-13: 978-0123741134
• Product Dimensions: 9.1 x 5.9 x 1.3 inches
• Shipping Weight: 1.8 pounds (View shipping rates and policies)
• Average Customer Review: 4.0 out of 5 stars  See all reviews (1 customer review)
• Amazon Best Sellers Rank: #2,931,973 in Books (See Top 100 in Books)

Customer Reviews

Most Helpful Customer Reviews

4.0 out of 5 stars dominated by molecular biology, August 11, 2008

By 

W Boudville (Terra, Sol 3) - See all my reviews
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This review is from: Vitamin K, Volume 78 (Vitamins and Hormones) (Hardcover)

It is impressive how the papers tend to focus at the molecular level. Several describe proposed reaction mechanisms at a fineness of detail that would have been undreamed of 20 years ago.

It appears that we are rapidly approaching a fundamental understanding of how vitamins [and hormones] operate. Far removed from an empirical and gross systems level treatment.