I am not a doctor, but I did stay in a holiday inn express last night, so I guess that qualifies me to be an expert on EVERYTHING - just like all doctors are...right. But seriously, here is the two cents of a major league skeptic who thinks this book has a lot of value.
I think it is fine to be skeptical about some of this science, as the doctor from San Jose points out, but it doesn't logically follow that just because the science isn't perfect that the ideas in this book are wrong (which seems to be the implication). In fact, I would say that empirical evidence tends to support the author's ideas, and that the idea that men and women think totally differently is not a particularly wild one. Focusing only on the science misses the point, and I couldn't disagree more with the statement, "If you want a healthy relationship you don't need to read a book to learn how." EVERYONE struggles with relationships, and if reading books or talking to friends or, god forbid, even talking to a shrink doctor, helps you, then that is great and you should go for it. Books can provide perspective, advice and understanding, and, in this particular case they can shed light on behaviours, and it is easier to tolerate a behavior if you understand why.
Now I agree with the good doctor's opinion that it is easy to use "that's just the way I am" as an excuse for bad behavior, but the differences in memory, emotional tendencies and other things discussed in this book are not all behaviors, but in many cases really are "just the way we are." I would go further to argue that communication styles are also "just the way we are," because even if they are learned behaviors, they are totally ingrained by adulthood, so you have to learn to translate what people say from their way of thinking to yours in order to respond properly and have a meaningful dialog.
And this does filter into such everyday things as channel flipping and a host of other things that women don't understand about men. I think it filters into everything. My wife is finally understanding that when it takes me 10 or 20 seconds to process what she says when I am watching something interesting on TV, it is not because I am purposely ignoring her or am not interested in what she has to say. It's just that I can only concentrate on one thing at a time, and it takes a bit to change gears.
On a final note, the doctor closes by saying nobody changes and that you need to find someone rational, good and loving. OK, I believe that to be true, but in my limited experience, on the rationality front, women have the same capacity for rationality as men, but they are 100 times more likely to throw it by the wayside if it conflicts with their emotions. Most women I know don't make personal decisions after a rational thought process weighing all the factors. But because I know and accept that, it doesn't bother me that my wife is so irrational sometimes, and I don't try to solve all her problems with reason, like I try to do for myself. I do try to separate out the emotional issues from the logical ones sometimes, but most of the time she just needs someone to stand by her, listen, care and suppport her. My best advice to men is that to learn how to do that, and to women, is to learn how to forgive and understand us when we don't, because this isn't our natural tendency.