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Why We Age: What Science Is Discovering about the Body's Journey Through Life
 
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Why We Age: What Science Is Discovering about the Body's Journey Through Life [Hardcover]

Steven N. Austad (Author)
4.0 out of 5 stars  See all reviews (9 customer reviews)


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Book Description

0471148032 978-0471148036 May 23, 1997 1
Why has the life span of the average American increased from 48 to 75 years in this century alone?

. . . If the body is a machine that simply wears out, why do some cells seem immortal?
. . . Is there an aging gene? And can we control it?
. . . Can antioxidants and hormone therapy actually slow the aging process and extend life?

Steven Austad s compelling book investigates the history, the theories, and the personalities behind the quest to understand the nature of aging. Here is hard evidence from the front lines of research that science is finally closing in on the fundamental processes of human biology and life.

"Austad s book can be read with pleasure and profit by any intelligent person with a smattering of biological knowledge." Science

"In this clear, engrossing overview, Austad takes the sting out of a subject that will ultimately capture us all." Publishers Weekly

"Why We Age is remarkably rigorous in its analysis and thorough scope. . . . A comprehensive examination of its topic." Science Editors, Amazon.com

"The problem with long life is that one keeps getting older; here s an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process." Kirkus Reviews


Editorial Reviews

Amazon.com Review

Before we know why we age, we need to know how we age. According to Steven Austad, we should blame the process on rusting and cooking. Oxygen causes our cells to rust, and glucose causes some of our tissues to take on the qualities of cooked meat. If we eat less food, we cook more slowly and we live longer. So, why do we age? Austad claims that we've evolved to have a certain reproductive usefulness, and after that the species doesn't need us anymore. What about all the "antiaging" equations modern science promises? Generally, the best they can do is prevent premature death. Sound harsh? Well, that's life, and Why We Age is one of the most entertaining and comprehensive guides on aging that you'll find.

From Kirkus Reviews

The problem with long life is that one keeps getting older; here's an able and clearly written summary of the latest theories on why we age and what might be done to ameliorate the process. Austad, a biologist at the universities of Idaho and Washington and science advisor to NPR, begins with an examination of longevity. Despite anecdotal claims of ages in excess of 150 years, modern medicine has concluded that there is no evidence of a human living much past the age of 120. While the human life span has unquestionably undergone a dramatic increase during this century, almost all the gain has come in the elimination of infectious diseases, especially those of childhood. If a complete cure for cancer were discovered tomorrow, it would add at most a couple of years to the average life expectancy. Austad notes other fascinating patterns, such as a huge leap in the male death rate during the period of ``testosterone dementia'': adolescence and early maturity. The discussion then turns to the biological mechanisms of aging. Among the explanations that have become current at various times is the notion that aging and death are evolutionary mechanisms for removing obsolete stock from the gene pool. Another theory is that there is an arbitrary limit on the number of times a given cell can divide; Austad refutes these and other theories. Especially interesting is his examination of the relation between menopause and aging, and the use of hormone therapies to inhibit aging in older women. Finally, he turns to the current theories, scientific and otherwise, on therapies to postpone aging: reduced calorie intake, exercise, and such trendy nostrums as melatonin. While he is skeptical of many of the claims for such anti-aging therapies, he remains optimistic that continued research may enable our descendants to look forward to a longer and healthier lifespan than we can. -- Copyright ©1997, Kirkus Associates, LP. All rights reserved.

Product Details

  • Hardcover: 256 pages
  • Publisher: Wiley; 1 edition (May 23, 1997)
  • Language: English
  • ISBN-10: 0471148032
  • ISBN-13: 978-0471148036
  • Product Dimensions: 9.5 x 6.4 x 0.9 inches
  • Shipping Weight: 1.2 pounds
  • Average Customer Review: 4.0 out of 5 stars  See all reviews (9 customer reviews)
  • Amazon Best Sellers Rank: #674,356 in Books (See Top 100 in Books)

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Average Customer Review
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9 of 9 people found the following review helpful:
3.0 out of 5 stars Interesting, February 1, 2001
This book presents a thoroughly readable introduction to the science of aging, not just human aging, but aging among all animals. The author begins by pointing out that all claims for pockets of extraordinarily aged people in various corners of the world have always lacked documentation or other substantiation. He states that there is a limit to human longevity that has remained constant even as life expectancies have risen with improved health care and living conditions.

Austad's somewhat simplistic writing style seems geared towards readers of self-help bestsellers at times, and occasionally his analogies lack clarity. Early in the text he defines the beginning of aging as the time when the probability of death is at its minimum, which seems to be about age 11 in humans. While this may be the standard measure for the science of aging (?), Austad never compares this to ordinary people's measures. For instance, many lay people distinguish between aging and longevity. They accept that there is a limit to life but within that limit, they want to have the highest quality of life possible right up until the end. Such people might define aging as a decline in life quality due to pain or illness, and loss of balance, strength, or memory. Certainly, quality of life does not start to decline at age 11. Later in the book as Austad examines ways that people might lengthen their lives, he still never takes up the issue of quality of life. Austad argues that some of the things that people do to try to make themselves healthier (exercise, vitamins) have not been shown to increase longevity but he seems to overlook the fact that they might increase the quality of life so they still might be worthwhile.

Despite these weaknesses, the book is still a very good introduction to the science of aging. It summarizes much current research about aging in language that is accessible by anyone.

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9 of 9 people found the following review helpful:
4.0 out of 5 stars Amazing Answers to the Right Questions in Senescence, October 29, 1999
By A Customer
If you are interested in health and the body, and have a scientific background, I think that you will find this book amazing. This is NOT a metaphysical questioning of death or a magic list of life lengthening behaviors. It is an attempt to understand why we age. As Steven points out, we use the word "why" to mean "how" many times. While he admits that it is not uninteresting or useless to know how we age (the mechanics), he undertakes the question of WHY. He does have an answer. Ironically, understanding why we age (which makes it inevitable that we will die) does give some spiritual peace, as it is human nature to be perturbed by that which we can not rationally understand. Steven logically and completely dismisses many fallacies that we have about aging deeply engrained in to our beliefs, and supports his arguments with his own scientific work and that of others.

The book is filled with interesting little nuggets of trivia and insights in to timeless philosophical questions. Buy it. Read it.

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9 of 10 people found the following review helpful:
5.0 out of 5 stars An entertaining introduction to the science of aging, February 4, 2002
Why do we age? The simple answer is, there is no simple answer. The simplest "simple" answer is probably, we age because we live, and living wears our bodies out.

In order to live we breathe because our bodies use oxygen to convert food into energy. But in the process something called "oxidative damage" happens to our cells. In other words: we rust. Inevitably. The two other main reasons why bodies wear out are connected to glucose and "browning damage", and to self-repair mechanisms of our cells that fail to stop and lead to uncontrolled cell growth - what we call "cancer".

The three processes of rusting, browning and cancer are part of aging. They are "how" we age. But "why" do we age at all? Why don't we stay healthy for, say, 150 years and then simply drop dead? In very simple terms the reason is: aging is genetic. The genes do not care about the body after the body has served its purpose: to replicate the genes and ensure that they can replicate again. This is called the "selfish gene" theory, an expression coined by Richard Dawkins.

Gerontology, the study of aging, is a field of science in rapid growth. I do not claim to be a specialist; therefore I do not want to go into much detail here. Steven Austad's book explains very well "what science is discovering about the body's journey through life". He ends his book with a chapter of particular interest for women ("Reproductive Aging, Menopause, and Health"), and a chapter on our hopes of how to make the best of our ultimate genetic fate ("Slowing Aging and Extending Life: Remedies and Expectations").

Apart from Austad's humor - it can be both droll and dry - I have particularly enjoyed his short portraits of scientists in the field of gerontology and evolutionary biology, such as the geneticist J.B.S. Haldane, the immunologist Peter Medawar, the American scientist Raymond Pearl (who in 1938 produced the first paper analyzing the extent to which smoking reduced life expectancy, but also was of the opinion that people above 50 should forfeit their right to vote, because they would have grown too foolish), the German physiologist Max Rubner, the gerontologist Alex Comfort (who discovered the joy - and profitability - of sex), the biologist John Maynard Smith, and the two-time Nobel prize winner Linus Pauling.

Austad's cameo of Max Rubner is my favorite because of its psychological insight into the downside of dedication and narrow focus: "The first scientist to investigate the rate-of-living idea in any rigorous fashion was the German physiologist Max Rubner. Rubner could make people very uncomfortable with his Teutonic bluntness. He was noted for his long silences, punctuated with outbursts of aggressively sarcastic humor. But he was also an obsessively precise investigator of the energy contained in food and the use of that energy by animals. Like obsessives everywhere, he felt that the significance of his obsession was underappreciated by others."

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