Adrenomedullin in Cardiovascular Disease (Basic Science for the Cardiologist) (Hardcover)

~ Toshio Nishikimi (Editor) "In 1993, we discovered adrenomedullin (AM) in human pheochromocytoma tissue by monitoring the ability of the cell extracts to increase intracellular cyclic AMP (cAMP) levels..." (more)
Key Phrases: adrenomedullin expression, human adrenomedullin gene, adrenomedullin production, Biochem Biophys Res Commun, Biol Chem, Hypertens Res (more...)

Editorial Reviews

Product Description

Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has role in the pathogenesis of arteriosclerosis. Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

About the Author

Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.

Product Details

• Hardcover: 222 pages
• Publisher: Springer; 1 edition (April 28, 2005)
• Language: English
• ISBN-10: 0387254048
• ISBN-13: 978-0387254043
• Product Dimensions: 9.5 x 6.3 x 0.7 inches
• Shipping Weight: 1.4 pounds (View shipping rates and policies)
• Average Customer Review: No customer reviews yet. Be the first.
• Amazon.com Sales Rank: #4,197,446 in Books (See Bestsellers in Books)