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Nonviral Vectors for Gene Therapy, Part 2, Volume 54, Second Edition (Advances in Genetics) (Pt. 2)
 
 
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Nonviral Vectors for Gene Therapy, Part 2, Volume 54, Second Edition (Advances in Genetics) (Pt. 2) (Hardcover)

by Leaf Huang (Editor), Mien-Chie Hung (Editor), Ernst Wagner (Editor) "As with studies involving viral transduction, the delivery of naked nucleic acids can be broken down into several transport steps, including (1) transport of nuclei..." (more)
Key Phrases: hydrodynamic delivery, liver gene transfer, naked plasmid transfer, Gene Ther, Gene They, Cancer Res (more...)
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Editorial Reviews

Book Description
A thorough update on the field of non-viral vector research.

Product Description
The field of non-viral vector research has rapidly progressed since the publication of the first edition. This new edition is expanded to two separate volumes that contain in-depth discussions of different non-viral approaches, including cationic liposomes and polymers, naked DNA and various physical methods of delivery, as well as a comprehensive coverage of the molecular biological designs of the plasmid DNA for reduced toxicity, prolonged expression and tissue or disease specific genes. New developments such as the toxicity of the non-viral vectors and recent advances in nucleic acid therapeutics are fully covered in these volumes.

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Inside This Book (learn more)
First Sentence:
As with studies involving viral transduction, the delivery of naked nucleic acids can be broken down into several transport steps, including (1) transport of nuclei acids from the site of injection to the liver, (2) exit of nucleic acids out of the liver vessel lumen into contact with hepatocytes, (3) uptake by hepatocytes, (4) entry into the cytoplasm, and (5) entry into the nucleus. Read the first page
Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
hydrodynamic delivery, liver gene transfer, naked plasmid transfer, hepatic locus control region, vivo clectroporation, survivin promoter, transposase molecules, lipid vector, cell electropermeabilization, transposon system, persistent gene expression, bovine growth hormone polyadenylation signal, following gene transfer, plasmid injection, mechanical massage, hepatic gene expression, vivo electroporation, hydrodynamic injection, gene transfer agents, intramuscular gene transfer, gene expression cassettes, cancer gene therapy, gene therapy vectors, foreign gene expression, gene therapy studies
Key Phrases - Capitalized Phrases (CAPs): (learn more)
Gene Ther, Gene They, Cancer Res, Gene Med, Elsevier Inc, Nature Med, Nucleic Acids Res, Nature Biotechnol, Nature Genet, Cell Biol, Nature Rev, Genes Dev, Cell Mot, Trends Genet, Cancer Inst, Cell Biochem, Expert Opin, Methods Enzymol, Walter Reed, Care Med, Drug Deliv, Lung Cell Mol, Allergy Clin, Cancer Biol, Cell Sci
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