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Editorial Reviews
Product Description
A timely book for DNA researchers, Automated DNA Sequencing and Analysis reviews and assesses the state of the art of automated DNA sequence analysis-from the construction of clone libraries to the developmentof laboratory and community databases. It presents the methodologies and strategies of automated DNA sequence analysis in a way that allows them to be compared and contrasted. By taking a broad view of the process of automated sequence analysis, the present volume bridges the gap between the protocols supplied with instrument and reaction kits and the finalized data presented in the research literature. It will be an invaluable aid to both small laboratories that are interested in taking maximum advantageof automated sequence resources and to groups pursuing large-scale cDNA and genomic sequencing projects.
* The field of automation in DAN sequencing and analysis is rapidly moving. Hovever, as the technology becomes commonplace, those applying the techniques involved to their research fields need a text which both expands on the protocols supplied by manufacturers with their instruments and explains how to utilise the data produced. This book fulfils those needs, reviews the history of the art and provides pointers to future development.
Book Info
Institute for Genomic Research, Gaithersburg, Maryland. Handbook of protocols in current DNA sequencing, for researchers in genetics, molecular biology, and cell biology. Format is structured to allow contrast and comparison. Halftone illustrations.
See all Editorial Reviews
A timely book for DNA researchers, Automated DNA Sequencing and Analysis reviews and assesses the state of the art of automated DNA sequence analysis-from the construction of clone libraries to the developmentof laboratory and community databases. It presents the methodologies and strategies of automated DNA sequence analysis in a way that allows them to be compared and contrasted. By taking a broad view of the process of automated sequence analysis, the present volume bridges the gap between the protocols supplied with instrument and reaction kits and the finalized data presented in the research literature. It will be an invaluable aid to both small laboratories that are interested in taking maximum advantageof automated sequence resources and to groups pursuing large-scale cDNA and genomic sequencing projects.
* The field of automation in DAN sequencing and analysis is rapidly moving. Hovever, as the technology becomes commonplace, those applying the techniques involved to their research fields need a text which both expands on the protocols supplied by manufacturers with their instruments and explains how to utilise the data produced. This book fulfils those needs, reviews the history of the art and provides pointers to future development.
Book Info
Institute for Genomic Research, Gaithersburg, Maryland. Handbook of protocols in current DNA sequencing, for researchers in genetics, molecular biology, and cell biology. Format is structured to allow contrast and comparison. Halftone illustrations.
See all Editorial Reviews
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Inside This Book Citations: This book cites 39 books Explore: Citations | Books on Related Topics | Concordance | Text Stats Key Phrases - SIPs: final consensus sequence, final contig, magnetic module, contig editor, nested deletion sets (more) Key Phrases - CAPs: Nucleic Acids Res, Nature Genet, Methods Enzymol, Cold Spring Harbor, Applied Biosystems (more) Browse Sample Pages: Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover | Surprise Me! |
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Inside This Book
(learn more)
First Sentence:
The GenBank genetic sequence database, which contained only 15 million nucleotides in 1987, has nearly doubled its size in each of the subsequent 5 years. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
final consensus sequence, final contig, magnetic module, contig editor, nested deletion sets, contextual arrays, contig merge, reverse sequencing, trace editor, frameshift errors, binary coding method, termination mixture, cosmid sequence, oligomer yields, candidate exons, consistent coverings, phage supernatant, abundant clones, cycle sequencing reactions, oligomer separations, thermal ramp, overlap strength, sequencing buffer, chimeric clones, sequencing templates Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Nature Genet, Methods Enzymol, Cold Spring Harbor, Applied Biosystems, New York, Academic Press, San Diego, Department of Energy, Molecular Cloning Techniques, Computer Society Press, Technical Report, Hawaii International Conference, Department of Computer Science, Boehringer Mannheim, Los Alamitos, Los Alamos National Laboratory, System Sciences, University of Arizona, Gene Clean, Laboratory Manual, Lawrence Berkeley Laboratory, Human Genome Center, Palo Alto, Practical Approach New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover | Surprise Me!
The GenBank genetic sequence database, which contained only 15 million nucleotides in 1987, has nearly doubled its size in each of the subsequent 5 years. Read the first page Key Phrases - Statistically Improbable Phrases (SIPs): (learn more)
final consensus sequence, final contig, magnetic module, contig editor, nested deletion sets, contextual arrays, contig merge, reverse sequencing, trace editor, frameshift errors, binary coding method, termination mixture, cosmid sequence, oligomer yields, candidate exons, consistent coverings, phage supernatant, abundant clones, cycle sequencing reactions, oligomer separations, thermal ramp, overlap strength, sequencing buffer, chimeric clones, sequencing templates Key Phrases - Capitalized Phrases (CAPs): (learn more)
Nucleic Acids Res, Nature Genet, Methods Enzymol, Cold Spring Harbor, Applied Biosystems, New York, Academic Press, San Diego, Department of Energy, Molecular Cloning Techniques, Computer Society Press, Technical Report, Hawaii International Conference, Department of Computer Science, Boehringer Mannheim, Los Alamitos, Los Alamos National Laboratory, System Sciences, University of Arizona, Gene Clean, Laboratory Manual, Lawrence Berkeley Laboratory, Human Genome Center, Palo Alto, Practical Approach New!
Books on Related Topics | Concordance | Text Stats Browse Sample Pages:
Front Cover | Copyright | Table of Contents | Excerpt | Index | Back Cover | Surprise Me!
Citations (learn more)
This book cites 39
books:
See all 39 books this book cites
- Molecular Cloning: A Laboratory Manual (3-Volume Set) by Joseph Sambrook on 5 pages
- Atlas of Protein Sequence and Structure (Vol 5, Supplement 3) by Margaret O. Dayhoff on page 265, and page 287
- Nucleic Acids Sequencing: A Practical Approach (Practical Approach Series) by C. J. Howe on page 48, and page 258
- Nucleic Acids Sequencing by Howe on page 48, and page 258
- Cell Biology (Molecular and Cell Biochemistry Series) by C. A. Smith on page 50
See all 39 books this book cites
